机构

• 上海药物研究所 [8]

采集方式

• OAI收割 [8]

内容类型

• 期刊论文 [8]

发表日期

• 2025 [1]
• 2024 [2]
• 2007 [2]
• 2006 [3]

学科主题

• Chemistry [2]
• Biochemist... [1]
• Biotechnol... [1]

筛选

浏览/检索结果: 共8条，第1-8条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择题名升序题名降序提交时间升序提交时间降序作者升序作者降序发表日期升序发表日期降序 Discovery of peptidomimetic spiropyrrolidine derivatives as novel 3CLpro inhibitors against SARS-CoV-2 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 281, 页码: 22 作者:  Guma, Samuel Desta;  Zhou, Zhaoyin;  Song, Kang;  Yang, Feipu;  Suo, Jin   |  收藏  |  浏览/下载：8/0  |  提交时间：2024/12/11 SARS-CoV-2  3CL pro inhibitors  Peptidomimetics  Spiropyrrolidine derivatives   Structure-guided design and photochemical synthesis of new carbamo (dithioperoxo)thioates with improved potencies to SARS-CoV-2 3CLpro 期刊论文  OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY, 2024, 卷号: 114, 页码: 9 作者:  Yin, De-Hang;  Xin, Jie;  Chen, Shizhao;  Li, Shuai-Shuai;  Li, Zi-Ying   |  收藏  |  浏览/下载：13/0  |  提交时间：2024/12/11 SARS-CoV-2  Disulfiram  Carbamo(dithioperoxo)thioates  Photochemistry  3CL pro   Discovery of the potent covalent inhibitor with an acrylate warhead for SARS-CoV-2 3CL protease 期刊论文  OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2024, 卷号: 112, 页码: 5 作者:  Shen, Wen;  Chen, Xinyao;  Zhou, Liping;  Cheng, Yan;  Zhang, Yan   |  收藏  |  浏览/下载：22/0  |  提交时间：2024/10/21 COVID-19  SARS-CoV-2 3CL pro inhibitor  Drug design  Antiviral activities   Design and synthesis of a novel fluorescent peptide substrate of SARS-CoV 3CL(pro) and studies on its enzymatic kinetics 期刊论文  OAI收割 CHEMICAL JOURNAL OF CHINESE UNIVERSITIES-CHINESE, 2007, 卷号: 28, 期号: 1, 页码: 79-82 作者:  Wan Hui-Xin;  Chen Li-Li;  Li Xin;  Wang Xin;  Hu Ding-Yu   |  收藏  |  浏览/下载：11/0  |  提交时间：2019/01/08 fluorescence resonance energy transfer(FRET)  SARS-CoV 3CL(pro)  fluorescent probe  LC-MS   Binding interaction of quereetin-3-beta-galactoside and its synthetic derivatives with SARS-CoV 3CL(pro): Structure-activity relationship studies reveal salient pharmacophore features 期刊论文  OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY, 2006, 卷号: 14, 期号: 24, 页码: 8295-8306 作者:  Chen, Lili;  Li, Jian;  Luo, Cheng;  Liu, Hong;  Xu, Weijun   |  收藏  |  浏览/下载：22/0  |  提交时间：2019/01/08 SARS-CoV 3CL(pro)  virtual screening  quercetin-3-beta-galactoside  molecular modeling  structure-activity relationships   Discovering severe acute respiratory syndrome coronavirus 3CL protease inhibitors: Virtual screening, surface plasmon resonance, and fluorescence resonance energy transfer assays 期刊论文  OAI收割 JOURNAL OF BIOMOLECULAR SCREENING, 2006, 卷号: 11, 期号: 8, 页码: 915-921 作者:  Chen, Lili;  Chen, Shuai;  Gui, Chunshan;  Shen, Jianhua;  Shen, Xu   |  收藏  |  浏览/下载：13/0  |  提交时间：2019/01/08 SARS  SARS-CoV 3CL(pro)  inhibitor  virtual screening  SPR  FRET