中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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上海药物研究所 [58]
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期刊论文 [158]
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Charting new paradigms for CAR-T cell therapy beyond current Achilles heels
期刊论文
OAI收割
FRONTIERS IN IMMUNOLOGY, 2024, 卷号: 15, 页码: 12
作者:
Li, Ying
;
Hu, Zhenhua
;
Li, Yuanyuan
;
Wu, Xiaoyan
  |  
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2024/06/27
chimeric antigen receptor
immunotherapy
allogeneic universal CAR-T cells
in vivo CAR-T cell
Achilles heels
TPN10475 Constrains Effector T Lymphocytes Activation and Attenuates Experimental Autoimmune Encephalomyelitis Pathogenesis by Facilitating TGF-β Signal Transduction
期刊论文
OAI收割
JOURNAL OF NEUROIMMUNE PHARMACOLOGY, 2024, 卷号: 19, 期号: 1, 页码: 16
作者:
Wang, Chun
;
Jiang, Xiangrui
;
Lv, Jie
;
Zhuang, Wei
;
Xie, Ling
  |  
收藏
  |  
浏览/下载:34/0
  |  
提交时间:2024/04/09
Experimental autoimmune encephalomyelitis
TGF-beta signal transduction
Effector CD4(+) T cells activation
Th/Treg
Cell migration
TPN10475 alleviates concanavalin A-induced autoimmune hepatitis by limiting T cell development and function through inhibition of PI3K-AKT pathway
期刊论文
OAI收割
INTERNATIONAL IMMUNOPHARMACOLOGY, 2023, 卷号: 125, 页码: 13
作者:
Wang, Chun
;
Han, Mengyao
;
Li, Xinhang
;
Lv, Jie
;
Zhuang, Wei
  |  
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2024/01/16
AIH
T cell
Pro-inflammatory
IFN-gamma
PI3K-AKT
Discovery of 7H-Pyrrolo[2,3-d]pyrimidine Derivatives as potent hematopoietic progenitor kinase 1 (HPK1) inhibitors
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 254, 页码: 15
作者:
Wu, Feifei
;
Li, Huiyu
;
An, Qi
;
Sun, Yaoliang
;
Yu, Jinghua
  |  
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2023/10/17
Hematopoietic progenitor kinase 1 (HPK1)
Cancer immunotherapy
Inhibitor
T cell
ASK120067 potently suppresses B-cell or T-cell malignancies in vitro and in vivo by inhibiting BTK and ITK
期刊论文
OAI收割
FRONTIERS IN PHARMACOLOGY, 2022, 卷号: 13, 页码: 9
作者:
Song, Peiran
;
Bai, Gang
;
Chan, Shingpan
;
Zhang, Tao
;
Tong, Linjiang
  |  
收藏
  |  
浏览/下载:41/0
  |  
提交时间:2023/04/10
Bruton's tyrosine kinase
interleukin-2-inducible T cell kinase
ASK120067
B-cell lymphoma
T-cell leukemia
In Situ Raman Spectroscopy and DFT Studies of the Phase Transition from Zircon to Reidite at High P-T Conditions
期刊论文
OAI收割
MINERALS, 2022, 卷号: 12, 期号: 12, 页码: 11
作者:
Gao, Yue
;
Zheng, Zhi
;
Zhao, Xia
;
Liu, Yuegao
;
Chen, Jiangzhi
  |  
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2023/01/30
zircon
reidite
phase transition
high P-T experiment
diamond anvil cell
in situ Raman spectroscopy
density functional theory
Identification of ST3GAL5 as a prognostic biomarker correlating with CD8(+) T cell exhaustion in clear cell renal cell carcinoma
期刊论文
OAI收割
FRONTIERS IN IMMUNOLOGY, 2022, 卷号: 13, 页码: 14
作者:
Liu, Jiakuan
;
Li, Meiqian
;
Wu, Jiajun
;
Qi, Qi
;
Li, Yang
  |  
收藏
  |  
浏览/下载:40/0
  |  
提交时间:2022/11/11
sialylation
clear cell renal cell carcinoma
ST3GAL5
CD8(+) T cell exhaustion
prognostic biomarker
The Efficacy of PD-1/PD-L1 Inhibitors in Patients with Liver Metastasis of Non-Small Cell Lung Cancer: A Real-World Study
期刊论文
OAI收割
CANCERS, 2022, 卷号: 14
作者:
Xie, Mingying
  |  
收藏
  |  
浏览/下载:38/0
  |  
提交时间:2022/12/22
liver metastasis
non-small cell lung cancer
PD-L1
PD-1
PD-L1 inhibitor
CD8+T cell
Impact of clinical and molecular features on efficacy and outcome of patients with non-small cell lung cancer receiving second-line osimertinib
期刊论文
OAI收割
BMC CANCER, 2022, 卷号: 22
作者:
Jin, Ying
;
Lin, Chen
;
Shi, Xun
;
He, Qiong
;
Yan, Junrong
  |  
收藏
  |  
浏览/下载:85/0
  |  
提交时间:2022/12/23
Clinical and molecular features
Efficacy and outcome
EGFR T790M mutation
Non-small-cell lung cancer
Osimertinib
Profiles of Proinflammatory Cytokines and T Cells in Patients With Tourette Syndrome: A Meta-Analysis
期刊论文
OAI收割
FRONTIERS IN IMMUNOLOGY, 2022, 卷号: 13, 页码: 10
作者:
Li, Ying
;
Wang, Xiaolin
;
Yang, Hanxue
;
Li, Yanlin
;
Gui, Jingang
  |  
收藏
  |  
浏览/下载:43/0
  |  
提交时间:2022/07/18
Tourette syndrome
proinflammatory cytokines
T cell
immunological dysfunction
meta-analysis