中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
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上海药物研究所 [61]
上海生物化学与细胞... [22]
合肥物质科学研究院 [10]
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期刊论文 [161]
会议论文 [4]
学位论文 [3]
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2025 [3]
2022 [9]
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2020 [10]
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浏览/检索结果:
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Cbl-b inhibitor NX-1607 activates MAPK/ERK signaling pathway and enhances T-cell activation
期刊论文
OAI收割
JOURNAL FOR IMMUNOTHERAPY OF CANCER, 2025, 卷号: 13, 期号: 5, 页码: 18
作者:
Zhu, Wenting
;
Lu, Shan
;
Jia, Li
;
Liu, Benjin
;
Song, Shanshan
  |  
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2025/08/20
Tumor microenvironment - TME
T cell
Immunotherapy
Immune modulatory
Immune Checkpoint Inhibitor
Dual roles of IRE1α inhibition in reversing mitochondrial ROS-induced CD8
+
T-cell senescence and exerting direct antitumor effects in multiple myeloma
期刊论文
OAI收割
JOURNAL FOR IMMUNOTHERAPY OF CANCER, 2025, 卷号: 13, 期号: 5, 页码: 13
作者:
Wan, Yike
;
Wang, Jingjing
;
Chen, Mengping
;
Wang, Junying
;
Nan, Fajun
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2025/07/25
Multiple Myeloma
Immunotherapy
T cell
Tumor microenvironment - TME
CD103
+
T Cells Eliminate Damaged Alveolar Epithelial Type II Cells Under Oxidative Stress to Prevent Lung Tumorigenesis
期刊论文
OAI收割
ADVANCED SCIENCE, 2025, 页码: 19
作者:
Xu, Yu
;
Luo, Haorui
;
Wang, Jiahao
;
Liu, Haifeng
;
Chen, Luonan
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2025/07/25
AT2 cell
CD103(+) T cell
lung adenocarcinoma
MED23
oxidative stress
tumorigenesis
Charting new paradigms for CAR-T cell therapy beyond current Achilles heels
期刊论文
OAI收割
FRONTIERS IN IMMUNOLOGY, 2024, 卷号: 15, 页码: 12
作者:
Li, Ying
;
Hu, Zhenhua
;
Li, Yuanyuan
;
Wu, Xiaoyan
  |  
收藏
  |  
浏览/下载:49/0
  |  
提交时间:2024/06/27
chimeric antigen receptor
immunotherapy
allogeneic universal CAR-T cells
in vivo CAR-T cell
Achilles heels
TPN10475 Constrains Effector T Lymphocytes Activation and Attenuates Experimental Autoimmune Encephalomyelitis Pathogenesis by Facilitating TGF-β Signal Transduction
期刊论文
OAI收割
JOURNAL OF NEUROIMMUNE PHARMACOLOGY, 2024, 卷号: 19, 期号: 1, 页码: 16
作者:
Wang, Chun
;
Jiang, Xiangrui
;
Lv, Jie
;
Zhuang, Wei
;
Xie, Ling
  |  
收藏
  |  
浏览/下载:47/0
  |  
提交时间:2024/04/09
Experimental autoimmune encephalomyelitis
TGF-beta signal transduction
Effector CD4(+) T cells activation
Th/Treg
Cell migration
TPN10475 alleviates concanavalin A-induced autoimmune hepatitis by limiting T cell development and function through inhibition of PI3K-AKT pathway
期刊论文
OAI收割
INTERNATIONAL IMMUNOPHARMACOLOGY, 2023, 卷号: 125, 页码: 13
作者:
Wang, Chun
;
Han, Mengyao
;
Li, Xinhang
;
Lv, Jie
;
Zhuang, Wei
  |  
收藏
  |  
浏览/下载:44/0
  |  
提交时间:2024/01/16
AIH
T cell
Pro-inflammatory
IFN-gamma
PI3K-AKT
Discovery of 7H-Pyrrolo[2,3-d]pyrimidine Derivatives as potent hematopoietic progenitor kinase 1 (HPK1) inhibitors
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 254, 页码: 15
作者:
Wu, Feifei
;
Li, Huiyu
;
An, Qi
;
Sun, Yaoliang
;
Yu, Jinghua
  |  
收藏
  |  
浏览/下载:41/0
  |  
提交时间:2023/10/17
Hematopoietic progenitor kinase 1 (HPK1)
Cancer immunotherapy
Inhibitor
T cell
ASK120067 potently suppresses B-cell or T-cell malignancies in vitro and in vivo by inhibiting BTK and ITK
期刊论文
OAI收割
FRONTIERS IN PHARMACOLOGY, 2022, 卷号: 13, 页码: 9
作者:
Song, Peiran
;
Bai, Gang
;
Chan, Shingpan
;
Zhang, Tao
;
Tong, Linjiang
  |  
收藏
  |  
浏览/下载:56/0
  |  
提交时间:2023/04/10
Bruton's tyrosine kinase
interleukin-2-inducible T cell kinase
ASK120067
B-cell lymphoma
T-cell leukemia
In Situ Raman Spectroscopy and DFT Studies of the Phase Transition from Zircon to Reidite at High P-T Conditions
期刊论文
OAI收割
MINERALS, 2022, 卷号: 12, 期号: 12, 页码: 11
作者:
Gao, Yue
;
Zheng, Zhi
;
Zhao, Xia
;
Liu, Yuegao
;
Chen, Jiangzhi
  |  
收藏
  |  
浏览/下载:34/0
  |  
提交时间:2023/01/30
zircon
reidite
phase transition
high P-T experiment
diamond anvil cell
in situ Raman spectroscopy
density functional theory
Identification of ST3GAL5 as a prognostic biomarker correlating with CD8(+) T cell exhaustion in clear cell renal cell carcinoma
期刊论文
OAI收割
FRONTIERS IN IMMUNOLOGY, 2022, 卷号: 13, 页码: 14
作者:
Liu, Jiakuan
;
Li, Meiqian
;
Wu, Jiajun
  |  
收藏
  |  
浏览/下载:61/0
  |  
提交时间:2022/11/11
sialylation
clear cell renal cell carcinoma
ST3GAL5
CD8(+) T cell exhaustion
prognostic biomarker