中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [63]
过程工程研究所 [14]
合肥物质科学研究院 [8]
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期刊论文 [128]
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De Novo Design of Structure-Tunable Multivalent Targeting Chimeras for Tumor-Targeted PD-L1 Degradation and Potentiated Cancer Immunotherapy
期刊论文
OAI收割
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2025, 页码: 17
作者:
Zhou, Huiling
;
Hou, Bo
;
Shan, Yiming
;
Huang, Lujia
;
Chen, Fangmin
  |  
收藏
  |  
浏览/下载:0/0
  |  
提交时间:2025/06/23
Combinatory therapy, Immune checkpoint blockade, Multivalent targeting chimeras
Tumor microenvironment
Tumor-specific PD-L1 degradation
Intratumoral lactic acid neutralization strategy for boosting chemoimmunotherapy using liposomal sodium bicarbonate
期刊论文
OAI收割
SCIENCE BULLETIN, 2024, 卷号: 69, 期号: 24, 页码: 3936-3948
作者:
Peng, Taoxing
;
Shao, Xinyue
;
Song, Wenqin
;
Xu, Weihua
;
Xiong, Wei
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2025/04/01
Sodium bicarbonate
Lactic acid neutralization
Tumor microenvironment normalization
Chemoimmunotherapy
PD-1 antibody
Ion-trapping barrier
Complexity made easy: Aggregation-induced emission small molecules for cancer diagnosis and phototherapies
期刊论文
OAI收割
AGGREGATE, 2024, 卷号: 5, 期号: 6
作者:
Chen, Luojia
;
Chen, Si-Ling
;
Yuan, Yuncong
;
Leng, Xiang
;
Xu, Xiaoyu
  |  
收藏
  |  
浏览/下载:0/0
  |  
提交时间:2025/06/04
aggregation-induced emission
near infrared
phototheranostics
small molecules
tumor microenvironment
An overview of the functions and mechanisms of APOBEC3A in tumorigenesis
期刊论文
OAI收割
ACTA PHARMACEUTICA SINICA B, 2024, 卷号: 14, 期号: 11, 页码: 4637-4648
作者:
Yang, Yuqi
;
Liu, Nan
;
Gong, Likun
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2025/01/06
Tumor-associated viruses
Tumor microenvironment
APOBEC3A
Deaminase
Mutation
DNA damage
Tumorigenesis
Tumor-associated viruses
Macrophage
Tumor microenvironment
Dynamic polyphenol nanoparticles boost cuproptosis-driven metalloimmunotherapy of breast cancer
期刊论文
OAI收割
NANO TODAY, 2024, 卷号: 58, 页码: 12
作者:
Zhang, Huijuan
;
Chen, Fangmin
;
Cheng, Wenhao
;
Lai, Yi
;
Hou, Bo
  |  
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2024/10/09
Polyphenol
Cuproptosis
Dynamic covalent bond
Cancer metalloimmunotherapy
Tumor immune microenvironment
Biomimetic Nucleic Acid Drug Delivery Systems for Relieving Tumor Immunosuppressive Microenvironment
期刊论文
OAI收割
PHARMACEUTICS, 2024, 卷号: 16, 期号: 8, 页码: 21
作者:
Yan, Wenlu
;
Cao, Ying
;
Yin, Qi
;
Li, Yaping
  |  
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2024/10/21
biomimetic
drug delivery system
nucleic acid
immunotherapy
tumor immunosuppressive microenvironment
Low molecular weight fucoidan LF2 improves the immunosuppressive tumor microenvironment and enhances the anti-pancreatic cancer activity of oxaliplatin
期刊论文
OAI收割
BIOMEDICINE & PHARMACOTHERAPY, 2024, 卷号: 173, 页码: 10
作者:
Deng, Zhenzhen
;
Qishan, Suo
;
Zhang, Quanbin
;
Wang, Jing
;
Yue, Yang
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2024/06/04
Fucoidan
Tumor microenvironment
Macrophages
Oxaliplatin
Small-molecule agents for cancer immunotherapy
期刊论文
OAI收割
ACTA PHARMACEUTICA SINICA B, 2024, 卷号: 14, 期号: 3, 页码: 905-952
作者:
Wang, Fang
;
Fu, Kai
;
Wang, Yujue
;
Pan, Can
;
Wang, Xueping
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2024/10/21
Cancer immunotherapy
Small-molecule agents
Immune checkpoints
Oncogenic signaling
Metabolic pathways
Cytokine/chemokine signaling
Antitumor immunity
Tumor immune microenvironment
Activating CD8
+
T Cells by Pt(IV) Prodrug-Based Nanomedicine and aPD-L1 Antibody for Enhanced Cancer Immunotherapy
期刊论文
OAI收割
ADVANCED MATERIALS, 2024, 页码: 15
作者:
Wang, Bin
;
Zhou, Jingyu
;
Li, Ruitong
;
Tang, Dongsheng
;
Cao, Zheng
  |  
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2024/04/09
chemotherapy
immunotherapy
immunogenic cell death
tumor immune microenvironment
PROTAC Prodrug-Integrated Nanosensitizer for Potentiating Radiation Therapy of Cancer
期刊论文
OAI收割
ADVANCED MATERIALS, 2024, 页码: 12
作者:
Zhang, Shunan
;
Lai, Yi
;
Pan, Jiaxing
;
Saeed, Madiha
;
Li, Shiqin
  |  
收藏
  |  
浏览/下载:41/0
  |  
提交时间:2024/04/09
active tumor targeting
nanosensitizer
PROTAC prodrug
radiation therapy
tumor microenvironment