机构

• 上海药物研究所 [6]
• 金属研究所 [3]
• 化学研究所 [2]
• 生态环境研究中心 [2]
• 大连化学物理研究所 [1]
• 过程工程研究所 [1]
• 更多

采集方式

• OAI收割 [17]

内容类型

• 期刊论文 [17]

发表日期

• 2025 [1]
• 2023 [2]
• 2022 [1]
• 2021 [3]
• 2020 [1]
• 2019 [1]
• 更多

学科主题

筛选

浏览/检索结果: 共17条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择题名升序题名降序提交时间升序提交时间降序作者升序作者降序发表日期升序发表日期降序 Discovery of novel covalent stabilizers for p53 Y220C using structure-based drug discovery methods 期刊论文  OAI收割 MOLECULAR DIVERSITY, 2025, 页码: 14 作者:  Wen, Yiming;  Xu, Peijia;  Chen, Yijie;  Meng, Jingyi;  Zheng, Mingyue   |  收藏  |  浏览/下载：12/0  |  提交时间：2025/04/01 p53 Y220C  Covalent stabilizer  Virtual screening  Molecular dynamics  DNA binding  Structure-activity relationship  Cancer therapy   Structure-Based Design of Potent Peptidomimetic Inhibitors Covalently Targeting SARS-CoV-2 Papain-like Protease 期刊论文  OAI收割 INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2023, 卷号: 24, 期号: 10, 页码: 15 作者:  Wang, Qian;  Chen, Guofeng;  He, Jian;  Li, Jiameng;  Xiong, Muya   |  收藏  |  浏览/下载：35/0  |  提交时间：2023/10/17 SARS-CoV-2  papain-like protease  covalent inhibitor  co-crystal structure  in vitro assay   Design, synthesis and biological evaluation of KRASG12C-PROTACs 期刊论文  OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY, 2023, 卷号: 78, 页码: 14 作者:  Zhang, Xiaoyi;  Zhao, Tong;  Sun, Minghao;  Li, Pei;  Lai, Mengzhen   |  收藏  |  浏览/下载：27/0  |  提交时间：2023/04/10 KRASG12C  PROTAC  Covalent inhibitors  Structure-activity relationships (SARs)  Anticancer   In silico screening-based discovery of novel covalent inhibitors of the SARS-CoV-2 3CL protease 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 231, 页码: 8 作者:  Xiong, Muya;  Nie, Tianqing;  Shao, Qiang;  Li, Minjun;  Su, Haixia   |  收藏  |  浏览/下载：35/0  |  提交时间：2022/06/15 SARS-CoV-2 3C-Like protease  Covalent inhibitor  Virtual screening  Crystal structure   Preparation of thermal stable supported metal (Cu, Au, Pd) nanoparticles via cross-linking cellulose gel confinement strategy 期刊论文  OAI收割 COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS, 2021, 卷号: 624, 页码: 9 作者:  Peng, Weidan;  Yan, Yukun;  Zhang, Dawei;  Zhou, Yangtao;  Na, Duo   |  收藏  |  浏览/下载：97/0  |  提交时间：2021/10/15 Cellulose hydrogel  Covalent cross-linking structure  Metal nanoparticles  Nitroaromatic hydrogenation   Piperazine-based two-dimensional covalent organic framework for high performance anodic lithium storage 期刊论文  OAI收割 ENERGY STORAGE MATERIALS, 2021, 卷号: 40, 页码: 124-138 作者:  Zhou, Rui;  Huang, Yang;  Li, Zhenhu;  Kang, Shuai;  Wang, Xiaomin   |  收藏  |  浏览/下载：130/0  |  提交时间：2021/08/20 Covalent organic frameworks (COFs)  Few-layered and microporous structure  Lithium-ion batteries (LIBs)  Anode  High specific capacity   Design, synthesis and biological evaluation of pyrazolo[3,4-d]pyridazinone derivatives as covalent FGFR inhibitors 期刊论文  OAI收割 ACTA PHARMACEUTICA SINICA B, 2021, 卷号: 11, 期号: 3, 页码: 781-794 作者:  Wu, Xiaowei;  Dai, Mengdi;  Cui, Rongrong;  Wang, Yulan;  Li, Chunpu   |  收藏  |  浏览/下载：53/0  |  提交时间：2021/05/24 Tyrosine kinase  Covalent FGFR inhibitors  Virtual screening  Pyrazolo[3,4-d] pyridazinone  Structure-activity relationships  Antitumor efficacy   Covalent coupling regulated thermal conductivity of poly(vinyl alcohol)/boron nitride composite film based on silane molecular structure 期刊论文  OAI收割 COMPOSITES PART A-APPLIED SCIENCE AND MANUFACTURING, 2020, 卷号: 137 作者:  Cheng, Hua;  Zhao, Kai;  Gong, Yi;  Wang, Xiao;  Wang, Rui   |  收藏  |  浏览/下载：72/0  |  提交时间：2020/10/26 Thermal conductivity  Covalent coupling  Molecular structure  Silane coupling agents  Poly(vinyl alcohol)  Functionalized boron nitride   Polyimides containing aliphatic/alicyclic segments in the main chains 期刊论文  OAI收割 PROGRESS IN POLYMER SCIENCE, 2019, 卷号: 92, 页码: 35 作者:  Zhuang, YB;  Seong, JG;  Lee, YM;  Zhuang, Yongbing;  Seong, Jong Geun   |  收藏  |  浏览/下载：74/0  |  提交时间：2019/06/14 Polyimides  Mixed-matrix Membranes  Polymerization  Wholly Alicyclic Polyimides  Monomers  Covalent Organic Frameworks  Aliphatic/alicyclic  Gas Permeation Properties  Structure-performance Relationship  Spontaneous Molecular-orientation  Applications  Processable Colorless Polyimides  Room-temperature Phosphorescence  Fully Aliphatic Polyimides  Enhanced Thermal-stability  Incorporating Trogers Base   Targeted synthesis of visible-light-driven covalent organic framework photocatalyst via molecular design and precise construction 期刊论文  OAI收割 APPLIED CATALYSIS B-ENVIRONMENTAL, 2018, 卷号: 239, 页码: 147-153 作者:  Yin, Bing;  He, Sijing;  Cai, Yaqi;  Niu, Hongyun   |  收藏  |  浏览/下载：288/0  |  提交时间：2019/06/20 Covalent organic frameworks  Molecular engineering  Tunable band structure  Visible-light-driven  Photocatalysis