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浏览/检索结果: 共14条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择题名升序题名降序提交时间升序提交时间降序作者升序作者降序发表日期升序发表日期降序 In-depth urinary and exosome proteome profiling analysis identifies novel biomarkers for diabetic kidney disease 期刊论文  OAI收割 SCIENCE CHINA-LIFE SCIENCES, 2023, 页码: 17 作者:  Du, Shichun;  Zhai, Linhui;  Ye, Shu;  Wang, Le;  Liu, Muyin   |  收藏  |  浏览/下载：18/0  |  提交时间：2023/10/17 diabetic kidney disease  type 2 diabetes mellitus  urinary proteome  urinary exosome proteome  biomarkers   2型糖尿病患者周围神经病变预测模型的构建 期刊论文  OAI收割 护理学杂志, 2023, 卷号: 38 作者:  李梦圆;  马学娅;  张小玉;  孙婷;  李素梅   |  收藏  |  浏览/下载：3/0  |  提交时间：2024/11/20 type 2 diabetes mellitus  diabetic peripheral neuropathy  clinical examination with 5 methods  nerve conduction study  vibration perception threshold  local thermal hyperemia  nomogram  prediction model  2型糖尿病  糖尿病周围神经病变  临床5项筛查  神经传导检查  震动感觉阈值  局部热充血  列线图  预测模型   Development of FABP4/5 inhibitors with potential therapeutic effect on type 2 Diabetes Mellitus 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 224, 页码: 14 作者:  He, Yu-Long;  Chen, Meng-Ting;  Wang, Ting;  Zhang, Ming-Ming;  Li, Ying-Xia   |  收藏  |  浏览/下载：59/0  |  提交时间：2021/11/04 Type 2 diabetes mellitus  Dual FABP4/5 inhibitors  Anti-lipolytic and anti-inflammatory effects  Metabolic stability  Anti-diabetic activities   Discovery of 5-(3-bromo-2-(2,3-dibromo-4,5-dimethoxybenzyl)-4,5-dimethoxybenzylidene)thiazolidine-2,4-dione as a novel potent protein tyrosine phosphatase 1B inhibitor with antidiabetic properties 期刊论文  OAI收割 BIOORGANIC CHEMISTRY, 2021, 卷号: 108, 页码: 13 作者:  Jiang, Bo;  Luo, Jiao;  Guo, Shuju;  Wang, Lijun   |  收藏  |  浏览/下载：38/0  |  提交时间：2021/05/11 Type 2 diabetes mellitus  Protein tyrosine phosphatase 1B inhibitors  Thiazolidinedione  Insulin signaling  Anti-diabetic activities   D-ribose is elevated in T1DM patients and can be involved in the onset of encephalopathy 期刊论文  OAI收割 AGING-US, 2019, 卷号: 11, 期号: 14, 页码: 4943-4969 作者:  Yu, Lexiang;  Chen, Yao;  Xu, Yong;  He, Tao;  Wei, Yan   |  收藏  |  浏览/下载：69/0  |  提交时间：2019/10/25 D-ribose  benfotiamine (BTMP)  cognitive impairment  type 1 diabetic encephalopathy  type 1 diabetes mellitus (T1DM)  diabetic encephalopathy   Anti-diabetic Effect of Punica granatum Flower Polyphenols Extract in Type 2 Diabetic Rats: Activation of Akt/GSK-3 beta and Inhibition of IRE1 alpha-XBP1 Pathways 期刊论文  OAI收割 FRONTIERS IN ENDOCRINOLOGY, 2018, 卷号: 9 作者:  Tang, Dan;  Liu, Liu;  Ajiakber, Dildar;  Ye, Jianping;  Xu, Jianjun   |  收藏  |  浏览/下载：80/0  |  提交时间：2019/01/08 type 2 diabetes mellitus  Punica granatum L. flower  anti-diabetic herb  oral glucose tolerance test  endoplasmic reticulum stress  insulin resistance   Discovery of novel bromophenol 3,4-dibromo-5-(2-bromo-3,4-dihydroxy-6-(isobutoxymethyl)benzyl)benzene-1,2-diol as protein tyrosine phosphatase 1B inhibitor and its anti-diabetic properties in C57BL/KsJ-db/db mice 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2013, 卷号: 64, 页码: 129-136 作者:  Jiang, Bo;  Guo, Shuju;  Shi, Dayong;  Guo, Chao;  Wang, Tao 收藏  |  浏览/下载：29/0  |  提交时间：2014/07/17 Type 2 diabetes mellitus  Protein tyrosine phosphatase 1B  Bromophenol  Anti-diabetic activities   Luteolin attenuates neuronal apoptosis in the hippocampi of diabetic encephalopathy rats 期刊论文  OAI收割 NEURAL REGENERATION RESEARCH, 2013, 卷号: 8, 期号: 12, 页码: 1071-1080 作者:  Ren Guiru;  Kong Jingjing;  Jia Ning;  Shang Xiuli   |  收藏  |  浏览/下载：15/0  |  提交时间：2021/02/26 OXIDATIVE STRESS  CELL-DEATH  DYSFUNCTION  DISEASE  neural regeneration  brain injury  diabetic mellitus  luteolin  apoptosis  learning and memory  spatial recognition memory  nerve cells  hippocampus  anti-oxidation  neuroregeneration   PID control of glucose concentration in subjects with type 1 diabetes based on a simplified model: An in silico trial (EI CONFERENCE) 会议论文  OAI收割 10th World Congress on Intelligent Control and Automation, WCICA 2012, July 6, 2012 - July 8, 2012, Beijing, China 作者:  Yu L. 收藏  |  浏览/下载：29/0  |  提交时间：2013/03/25 An artificial pancreas system (APS) mimics the function of a real pancreas through monitoring a diabetic's blood glucose and administering the right dose of insulin via an automatic control loop. It is hailed as a promising cure of diabetes  though this technology is still years away from commercial use due to a few technological bottlenecks. The simulation model of insulin-glucose metabolism of type 1 diabetes mellitus (T1DM) is an essential part of APS. In order to simplify the parameter identification task so that the model can be implemented electronically with ease  this paper presents a simplified model based on Routh approximation model reduction method. The results show that the approximation error between the simplified model and the original model is so small that can be neglected. Based on the simplified model  a PID controller is designed to maintain normoglycemia (90mg/dl) in subjects with T1DM. The in silico simulation results show that the glucose concentration is controlled well  the risk of hyperglycemia and hypoglycemia is reduced a lot. This suggests that the simplified model describes the insulin-glucose metabolism process accurately  and the PID control algorithm is well-suitable to guide the further development of an APS. 2012 IEEE.   Euonymus alatus in the Treatmentof Diabetic Nephropathy in Rats 期刊论文  OAI收割 The American Journal of Chinese Medicine, 2012, 卷号: 40, 期号: 6, 页码: 1177–1187 作者:  Bai Chang;  Chuan Jin;  Wei Zhang;  Li Kong;  Ju-Hong Yang   |  收藏  |  浏览/下载：22/0  |  提交时间：2017/07/24 Diabetic Nephropathy  Diabetes Mellitus  Streptozotocin  Euonymus Alatus  Irbesartan  Plant Medica  Glomerulosclerosis  Transform Growth Factor Β1