中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [9]
过程工程研究所 [3]
化学研究所 [2]
自动化研究所 [2]
沈阳自动化研究所 [1]
采集方式
OAI收割 [17]
内容类型
期刊论文 [17]
发表日期
2024 [1]
2021 [1]
2019 [3]
2016 [1]
2015 [4]
2013 [2]
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学科主题
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Visualization of nasal powder distribution using biomimetic human nasal cavity model
期刊论文
OAI收割
ACTA PHARMACEUTICA SINICA B, 2024, 卷号: 14, 期号: 1, 页码: 392-404
作者:
Su, Jiawen
;
Liu, Yan
;
Sun, Hongyu
;
Naeem, Abid
;
Xu, Huipeng
  |  
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2024/02/27
Nasal drug deposition
Nasal drug distribution
Nasal drug delivery
Biomimetic nasal model
Nasal powder
Three-dimensional reconstruction
Three-dimensional printing
Concentration optimization of combinatorial drugs using Markov chain-based models
期刊论文
OAI收割
BMC Bioinformatics, 2021, 卷号: 22, 期号: 1, 页码: 1-19
作者:
Ma S(马爽)
;
Dang D(党丹)
;
Wang WX(王文学)
  |  
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2021/10/03
Combinatorial drug optimization
Markov chain
Transition probability
Stationary balance distribution
Combinatorial therapy
Trained Macrophage Bioreactor for Penetrating Delivery of Fused Antitumor Protein
期刊论文
OAI收割
ACS APPLIED MATERIALS & INTERFACES, 2019, 卷号: 11, 期号: 26, 页码: 23018-23025
作者:
Zhang, Yu
;
Zhang, Yujie
;
Guo, Qin
;
Guo, Zhongyuan
;
Chen, Xinli
  |  
收藏
  |  
浏览/下载:43/0
  |  
提交时间:2020/07/01
macromolecular protein delivery
cell vector
tumor targeting
intratumoral drug distribution
breast cancer therapy
Preparation of ropivacaine loaded PLGA microspheres as controlled-release system with narrow size distribution and high loading efficiency
期刊论文
OAI收割
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS, 2019, 卷号: 562, 页码: 237-246
作者:
Li, Xun
;
Wei, Yi
;
Lv, Piping
;
Wu, Youbin
;
Ogino, Kenji
  |  
收藏
  |  
浏览/下载:120/0
  |  
提交时间:2019/04/03
Ropivacaine
PLGA microsphere
High drug loading
Narrow size distribution
Reduce cytotoxicity
Recent research and development of PLGA/PLA microspheres/nanoparticles: A review in scientific and industrial aspects
期刊论文
OAI收割
FRONTIERS OF CHEMICAL SCIENCE AND ENGINEERING, 2019, 卷号: 13, 期号: 1, 页码: 14, 27
作者:
Qi, F
;
Wu, J
;
Li, H
;
Ma, GH
;
Qi, Feng
  |  
收藏
  |  
浏览/下载:82/0
  |  
提交时间:2019/06/14
PLGA
DEXAMETHASONE INTRAVITREAL IMPLANT
microspheres
SUPERCRITICAL EMULSION EXTRACTION
drug delivery system
MEMBRANE EMULSIFICATION TECHNIQUE
stability
SUSTAINED-RELEASE
manufacturing
IN-VITRO
PICKERING EMULSIONS
FACIAL LIPOATROPHY
PLA MICROCAPSULES
SIZE DISTRIBUTION
GROWTH-FACTOR
The modulation of tumor vessel permeability by thalidomide and its impacts on different types of targeted drug delivery systems in a sarcoma mouse model
期刊论文
OAI收割
JOURNAL OF CONTROLLED RELEASE, 2016, 卷号: 238, 页码: 186-196
作者:
Wang, Dan
;
Fu, Jijun
;
Shi, Yujie
;
Peng, Dong
;
Yuan, Lan
  |  
收藏
  |  
浏览/下载:45/0
  |  
提交时间:2016/12/26
Targeted Drug Delivery Systems
Animal Model Of Epr Effect
Tumor Vessel Permeability
Thalidomide
Antitumor Efficacy
Distribution
Penetration profile and human cadaver skin distribution of finasteride from vesicular nanocarriers
期刊论文
OAI收割
DRUG DELIVERY, 2015, 卷号: 22, 期号: 8, 页码: 1003-1009
作者:
Rao, Yuefeng
;
Zheng, Feiyue
;
Liang, Xingguang
;
Wang, Huiyuan
;
Zhang, Jin
  |  
收藏
  |  
浏览/下载:124/0
  |  
提交时间:2019/01/08
Drug delivery
ethosomes
finasteride
human cadaver skin
in vitro percutaneous permeation
liposomes
skin distribution
Mass Spectrometry Imaging: Applications in Drug Distribution Studies
期刊论文
OAI收割
CURRENT DRUG METABOLISM, 2015, 卷号: 16, 期号: 9, 页码: 807-815
作者:
Zhao, Yuan-Sheng
;
Li, Chuan
  |  
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2019/01/08
Drug distribution
MALDI
Mass spectrometry imaging
metabolites
preclinicalpharmacokineticsoftpn729maanovelpde5inhibitorandpredictionofitshumanpharmacokineticsusingapbpkmodel
期刊论文
OAI收割
actapharmacologicasinica, 2015, 卷号: 36, 期号: 12, 页码: 1528
作者:
Gao Zhiwei
;
Zhu Yunting
;
Yu Mingming
;
Zan Bin
;
Liu Jia
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2020/07/01
HUMAN DRUG CLEARANCE
PHOSPHODIESTERASE-5 INHIBITORS
CLINICAL PHARMACOKINETICS
ERECTILE DYSFUNCTION
TISSUE DISTRIBUTION
ORAL PHARMACOKINETICS
RECEPTOR ANTAGONIST
DIVERSE COMPOUNDS
IN-VIVO
ABSORPTION
TPN729MA
PDE5 inhibitor
erectile dysfunction
pharmacokinetics
human PK prediction
physiologically based pharmacokinetic model
isomerselectivedistributionof3nbutylphthalidenbphydroxylatedmetabolites3hydroxynbpand10hydroxynbpacrosstheratbloodbrainbarrier
期刊论文
OAI收割
actapharmacologicasinica, 2015, 卷号: 36, 期号: 12, 页码: 1520
作者:
Diao Xingxing
;
Zhong Kan
;
Li Xiuli
;
Zhong Dafang
;
Chen Xiaoyan
  |  
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2020/07/01
CANCER RESISTANCE PROTEIN
P-GLYCOPROTEIN P-GP/ABCB1
TANDEM MASS-SPECTROMETRY
FOCAL CEREBRAL-ISCHEMIA
PLASMA-PROTEIN
CHIRAL 3-N-BUTYLPHTHALIDE
TISSUE DISTRIBUTION
DRUG DISCOVERY
BINDING
PENETRATION
3-n-butylphthalide (NBP)
3-OH-NBP
10-OH-NBP
blood-brain barrier
isomer-selective
drug plasma protein binding
drug brain protein binding
P-gp/BCRP
cerebral ischemia