机构

• 上海药物研究所 [11]
• 长春应用化学研究所 [5]
• 计算技术研究所 [1]
• 化学研究所 [1]
• 过程工程研究所 [1]
• 自动化研究所 [1]
• 更多

采集方式

• OAI收割 [22]

内容类型

• 期刊论文 [22]

发表日期

• 2024 [4]
• 2022 [1]
• 2021 [1]
• 2020 [2]
• 2019 [1]
• 2018 [2]
• 更多

学科主题

筛选

浏览/检索结果: 共22条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择题名升序题名降序提交时间升序提交时间降序作者升序作者降序发表日期升序发表日期降序 Recent Development of Small Molecule Drugs for the Treatment of Osteoarthritis 期刊论文  OAI收割 PROGRESS IN CHEMISTRY, 2024, 卷号: 36, 期号: 12, 页码: 1849-1858 作者:  Zhang, Xiaofei;  Yang, Chunhao   |  收藏  |  浏览/下载：6/0  |  提交时间：2025/04/01 osteoarthritis  small molecule drugs  drug development   TRIP13-a potential drug target in cancer pharmacotherapy 期刊论文  OAI收割 BIOORGANIC CHEMISTRY, 2024, 卷号: 151, 页码: 11 作者:  Bunu, Samuel Jacob;  Cai, Haiyan;  Wu, Leyun;  Zhang, Hui;  Zhou, Zhaoyin   |  收藏  |  浏览/下载：11/0  |  提交时间：2024/09/26 AAA plus ATPase  TRIP13  Cancer  Drug target  Small-molecule inhibitors   DockingGA: enhancing targeted molecule generation using transformer neural network and genetic algorithm with docking simulation 期刊论文  OAI收割 BRIEFINGS IN FUNCTIONAL GENOMICS, 2024, 页码: 12 作者:  Gao, Changnan;  Bao, Wenjie;  Wang, Shuang;  Zheng, Jianyang;  Wang, Lulu   |  收藏  |  浏览/下载：18/0  |  提交时间：2024/05/20 molecule generation  molecule optimization  drug discovery  deep learning  drug design  genetic algorithm   Studying the Effects and Competitive Mechanisms of YOYO-1 on the Binding Characteristics of DOX and DNA Molecules Based on Surface-Enhanced Raman Spectroscopy and Molecular Docking Techniques 期刊论文  OAI收割 INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2024, 卷号: 25, 期号: 7 作者:  Li, Yanjie;  Li, Zhiwei;  Yun, Penglun;  Sun, Dan;  Niu, Yong   |  收藏  |  浏览/下载：23/0  |  提交时间：2024/07/18 SERS  molecular docking method  drug molecule  binding site  competitive mechanism   Structure-aware conditional variational auto-encoder for constrained molecule optimization 期刊论文  OAI收割 PATTERN RECOGNITION, 2022, 卷号: 126, 页码: 9 作者:  Yu, Junchi;  Xu, Tingyang;  Rong, Yu;  Huang, Junzhou;  He, Ran   |  收藏  |  浏览/下载：47/0  |  提交时间：2022/06/06 Molecule optimization  Conditional generation  Drug discovery   Targeting Protein Neddylation to Inactivate Cullin-RING Ligases by Gossypol: A Lucky Hit or a New Start? 期刊论文  OAI收割 DRUG DESIGN DEVELOPMENT AND THERAPY, 2021, 卷号: 15 作者:  Yu, Qing;  Sun, Yi   |  收藏  |  浏览/下载：41/0  |  提交时间：2021/03/15 anti-cancer drug  cullin-RING E3 ligases  natural product  high-throughput screen  neddylation  small-molecule inhibitors   Discovery of a novel third-generation EGFR inhibitor and identification of a potential combination strategy to overcome resistance 期刊论文  OAI收割 MOLECULAR CANCER, 2020, 卷号: 19, 期号: 1, 页码: 15 作者:  Zhang, Tao;  Qu, Rong;  Chan, Shingpan;  Lai, Mengzhen;  Tong, Linjiang   |  收藏  |  浏览/下载：93/0  |  提交时间：2020/07/01 Non-small cell lung cancer (NSCLC)  EGFR T790M  Small-molecule inhibitor  Drug resistance  Ack1   RNA Methylation m(6)A: A New Code and Drug Target? 期刊论文  OAI收割 CHINESE JOURNAL OF CHEMISTRY, 2020, 卷号: 38, 期号: 4, 页码: 420-421 作者:  Lai, Gan-Qiang;  Zhou, Lin-Lin;  Yang, Cai-Guang   |  收藏  |  浏览/下载：18/0  |  提交时间：2020/07/01 m(6)A  Epitranscriptomics  Small-molecule intervention  Drug discovery  RNA   A patent review of arginine methyltransferase inhibitors (2010-2018) 期刊论文  OAI收割 EXPERT OPINION ON THERAPEUTIC PATENTS, 2019, 卷号: 29, 期号: 2, 页码: 97-114 作者:  Li, Xiao;  Wang, Chen;  Jiang, Hao;  Luo, Cheng   |  收藏  |  浏览/下载：22/0  |  提交时间：2020/07/01 Arginine methylation  Protein arginine methyltransferases (PRMTs)  small molecule inhibitors  drug research and development   Computer-Aided Drug Design in Epigenetics 期刊论文  OAI收割 FRONTIERS IN CHEMISTRY, 2018, 卷号: 6 作者:  Lu, Wenchao;  Zhang, Rukang;  Jiang, Hao;  Zhang, Huimin;  Luo, Cheng   |  收藏  |  浏览/下载：44/0  |  提交时间：2019/01/08 drug discovery  epigenetics  small-molecule inhibitor  computer-aided drug design  virtual screening