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• OAI收割 [81]
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浏览/检索结果: 共84条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择题名升序题名降序提交时间升序提交时间降序作者升序作者降序发表日期升序发表日期降序 Interaction-Based Inductive Bias in Graph Neural Networks: Enhancing Protein-Ligand Binding Affinity Predictions From 3D Structures 期刊论文  OAI收割 IEEE TRANSACTIONS ON PATTERN ANALYSIS AND MACHINE INTELLIGENCE, 2024, 卷号: 46, 期号: 12, 页码: 8191-8208 作者:  Yang, Ziduo;  Zhong, Weihe;  Lv, Qiujie;  Dong, Tiejun;  Chen, Guanxing   |  收藏  |  浏览/下载：7/0  |  提交时间：2025/01/14 Proteins  Programmable logic arrays  Three-dimensional displays  Predictive models  Graph neural networks  Data models  Convolution  Protein-ligand binding affinity  graph neural networks  inductive bias  drug-target interaction  structure-based virtual screening   TRIP13-a potential drug target in cancer pharmacotherapy 期刊论文  OAI收割 BIOORGANIC CHEMISTRY, 2024, 卷号: 151, 页码: 11 作者:  Bunu, Samuel Jacob;  Cai, Haiyan;  Wu, Leyun;  Zhang, Hui;  Zhou, Zhaoyin   |  收藏  |  浏览/下载：11/0  |  提交时间：2024/09/26 AAA plus ATPase  TRIP13  Cancer  Drug target  Small-molecule inhibitors   In silico off-target profiling for enhanced drug safety assessment 期刊论文  OAI收割 ACTA PHARMACEUTICA SINICA B, 2024, 卷号: 14, 期号: 7, 页码: 2927-2941 作者:  Liu, Jin;  Gui, Yike;  Rao, Jingxin;  Sun, Jingjing;  Wang, Gang   |  收藏  |  浏览/下载：10/0  |  提交时间：2024/08/22 Drug safety  Off-target prediction  Adverse drug reactions  Toxicity  Molecular representation  Artificial intelligence   Substrate and Functional Diversity of Protein Lysine Post-translational Modifications 期刊论文  OAI收割 GENOMICS PROTEOMICS & BIOINFORMATICS, 2024, 卷号: 22, 期号: 1, 页码: 21 作者:  Hao, Bingbing;  Chen, Kaifeng;  Zhai, Linhui;  Liu, Muyin;  Liu, Bin   |  收藏  |  浏览/下载：4/0  |  提交时间：2024/12/16 Protein lysine PTM  Regulatory enzyme  PTM crosstalk  Drug target  Acylation   Eliminating drug target interference with specific antibody or its F(ab′)2 fragment in the bridging immunogenicity assay 期刊论文  OAI收割 BIOANALYSIS, 2024, 页码: 14 作者:  Deng, Xiaojie;  Hou, Yingying;  Yuan, Wenyi;  Yang, Hongzhou;  Guo, Ruowen   |  收藏  |  浏览/下载：295/0  |  提交时间：2024/04/09 anti-drug antibody  IgE  immunogenicity  mitigation  target interference   A proteomic landscape of pharmacologic perturbations for functional relevance 期刊论文  OAI收割 JOURNAL OF PHARMACEUTICAL ANALYSIS, 2024, 卷号: 14, 期号: 1, 页码: 128-139 作者:  Liu, Zhiwei;  Jiang, Shangwen;  Hao, Bingbing;  Xie, Shuyu;  Liu, Yingluo   |  收藏  |  浏览/下载：23/0  |  提交时间：2024/04/09 Proteomics  Drug  Perturbation  Drug target  Drug combination   Structural insights into the interaction of three Y- shaped ligands with PI3Kα 期刊论文  OAI收割 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2023, 卷号: 120, 期号: 34, 页码: 9 作者:  Zhou, Qingtong;  Liu, Xiao;  Neri, Dario;  Li, Wenxin;  Favalli, Nicholas   |  收藏  |  浏览/下载：24/0  |  提交时间：2023/12/08 phosphoinositide 3-kinase  drug target  ligand  binding pocket  chemical scaffold   ETCM v2.0: An update with comprehensive resource and rich annotations for traditional Chinese medicine 期刊论文  OAI收割 ACTA PHARMACEUTICA SINICA B, 2023, 卷号: 13, 期号: 6, 页码: 2559-2571 作者:  Zhang, Yanqiong;  Li, Xin;  Shi, Yulong;  Chen, Tong;  Xu, Zhijian   |  收藏  |  浏览/下载：57/0  |  提交时间：2023/10/17 Traditional Chinese medicine  Database  Target identification  Network visualization  New drug research and development  Molecular mechanism  Quality marker  Drug repurposing   Proteomic characterization of post-translational modifications in drug discovery 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2022, 页码: 18 作者:  Zhai, Lin-hui;  Chen, Kai-feng;  Hao, Bing-bing;  Tan, Min-jia   |  收藏  |  浏览/下载：25/0  |  提交时间：2023/04/10 proteomics  protein post-translational modification  drug target  off-target  drug mechanism  precision medicine   Conserved protein targets for developing pan-coronavirus drugs based on sequence and 3D structure similarity analyses 期刊论文  OAI收割 COMPUTERS IN BIOLOGY AND MEDICINE, 2022, 卷号: 145, 页码: 105455 作者:  Ma, Minfei;  Yang, Yanqing;  Wu, Leyun;  Zhou, Liping;  Shi, Yulong   |  收藏  |  浏览/下载：32/0  |  提交时间：2024/03/21 Pharmaceutical informatics  Drug design  Target discovery  Medicinal chemistry  Broad-spectrum drugs