中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [5]
生物物理研究所 [2]
上海生物化学与细胞生... [1]
昆明动物研究所 [1]
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OAI收割 [9]
内容类型
期刊论文 [9]
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2022 [3]
2021 [1]
2013 [1]
2012 [1]
2011 [1]
2010 [2]
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学科主题
1 [1]
Immunology [1]
Life Scien... [1]
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Development of a variant of dinutuximab with enhanced antitumor efficacy and reduced induction of neuropathic pain
期刊论文
OAI收割
FEBS OPEN BIO, 2022, 卷号: 12, 期号: 9, 页码: 1644-1656
作者:
Liu, Xin-Yuan
;
Chen, Yi-Li
;
Liu, Guo-Jian
;
Deng, Xiang-Nan
;
Cui, Yue
  |  
收藏
  |  
浏览/下载:43/0
  |  
提交时间:2022/09/30
ADCC
affinity maturation
antibody engineering
anti-GD2 antibodies
engineered Fc domain
humanized
Recent progress in assays for GPCR drug discovery
期刊论文
OAI收割
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY, 2022, 卷号: 323, 期号: 2, 页码: C583-C594
作者:
Guo, Shimeng
;
Zhao, Tingting
;
Yun, Ying
;
Xie, Xin
  |  
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2023/04/10
biased signaling
GPCR
high -throughput screening assays
humanized mouse model
protein
protein interaction
Transforming primary human hepatocytes into hepatocellular carcinoma with genetically defined factors
期刊论文
OAI收割
EMBO REPORTS, 2022, 页码: 17
作者:
Jiang, Zhiwu
;
Cheng, Lin
;
Wu, Zhiping
;
Zhou, Linfu
;
Wang, Haitao
  |  
收藏
  |  
浏览/下载:42/0
  |  
提交时间:2022/06/15
biomarkers
hepatocellular carcinoma
humanized mouse models
immunotherapy
oncogenes
Survival-Assured Liver Injury Preconditioning (SALIC) Enables Robust Expansion of Human Hepatocytes in Fah(-/-)Rag2(-/-)IL2rg(-/-) Rats
期刊论文
OAI收割
ADVANCED SCIENCE, 2021, 页码: 14
作者:
Zhang, Ludi
;
Ge, Jian-Yun
;
Zheng, Yun-Wen
;
Sun, Zhen
;
Wang, Chenhua
  |  
收藏
  |  
浏览/下载:46/0
  |  
提交时间:2021/11/04
bioreactor
humanized liver
liver xeno-repopulation
pharmacological study
Application of Humanized Mice in Drug Metabolism and Toxicity
期刊论文
OAI收割
Chinese Pharmaceutical Journal, 2013, 卷号: 48, 期号: 14, 页码: 1137-1142
作者:
Wu Zhitao
;
Ren Jin
;
Pan Guoyu
  |  
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2019/01/08
humanized mice
CYP450
drug metabolism
induction
inhibition
toxicity
HIV-1 immunopathogenesis in humanized mouse models
期刊论文
OAI收割
CELLULAR & MOLECULAR IMMUNOLOGY, 2012, 卷号: 9, 期号: 3, 页码: 237-244
Zhang, Liguo
;
张立国
;
Su, Lishan
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2013/12/24
HIV
humanized mice
pathogenesis
immune activation
Xeno-repopulation of Fah (-/-) Nod/Scid mice livers by human hepatocytes
期刊论文
OAI收割
SCIENCE CHINA-LIFE SCIENCES, 2011, 卷号: 54, 期号: 3, 页码: 227-234
作者:
Su, BL
;
Liu, CC
;
Xiang, D
;
Zhang, HB
;
Yuan, SM
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2015/07/22
human hepatocyte
humanized liver
cell transplantation
Fah gene knockout mice
Nod/Scid mice
Current humanized mouse models for studying human immunology and HIV-1 immuno-pathogenesis
期刊论文
OAI收割
SCIENCE CHINA-LIFE SCIENCES, 2010, 卷号: 53, 期号: 2, 页码: 195-203
Zhang Liguo
;
张立国
;
Meissner, Eric
;
Chen JianZhu
;
Su LiShan
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2013/12/24
Humanized mouse models
HIV-1
NOD/SCID/gammaC(-/-)
Rag2(-/-)/gammaC(-/-)
Reactivity of a humanized antibody (hPankoMab) towards a tumor-related MUC1 epitope (TA-MUC1) with various human carcinomas
期刊论文
OAI收割
PATHOLOGY RESEARCH AND PRACTICE, 2010, 卷号: 206, 期号: 8, 页码: 585-589
作者:
Fan XN
;
Karsten U
;
Goletz S[*]
;
Cao Y[*]
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2016/03/24
Humanized antibody
PankoMab
MUC1
Carcinoma
In vivo