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Chinese Academy of Sciences Institutional Repositories Grid
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Acetylcholinesterase-independent protective effects of huperzine A against iron overload-induced oxidative damage and aberrant iron metabolism signaling in rat cortical neurons
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2016, 卷号: 37, 期号: 11, 页码: 1391-1400
作者:
Tao, Ling-xue
;
Huang, Xiao-tian
;
Chen, Yu-ting
;
Tang, Xi-can
;
Zhang, Hai-yan
  |  
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2019/01/08
Alzheimer's disease
huperzine A
iron
reactive oxygen species
mitochondria dysfunction
acetylcholinesterase
Reducing iron in the brain: a novel pharmacologic mechanism of huperzine A in the treatment of Alzheimer's disease
期刊论文
OAI收割
NEUROBIOLOGY OF AGING, 2014, 卷号: 35, 期号: 5, 页码: 1045-1054
作者:
Huang, Xiao-Tian
;
Qian, Zhong-Ming
;
He, Xuan
;
Gong, Qi
;
Wu, Ka-Chun
  |  
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2019/01/08
Huperzine A
Alzheimer's disease
Brain iron
Transferrin receptor 1
Double transgenic APPswe/PS1dE9 mice (APP/PS mice)
The neuronal amyloid precursor protein (APP)
Phase I study on the pharmacokinetics and tolerance of ZT-1, a prodrug of huperzine A, for the treatment of Alzheimer's disease
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2013, 卷号: 34, 期号: 7, 页码: 976-982
作者:
Jia, Jing-ying
;
Zhao, Qian-hua
;
Liu, Yun
;
Gui, Yu-zhou
;
Liu, Gang-yi
  |  
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2019/01/08
ZT-1
huperzine A
prodrug
AChE inhibitor
drug tolerance
pharmacokinetics
Alzheimer's disease
Quantitative proteomic analysis reveals the neuroprotective effects of huperzine A for amyloid beta treated neuroblastoma N2a cells
期刊论文
OAI收割
PROTEOMICS, 2013, 卷号: 13, 期号: 8, 页码: 1314-1324
作者:
Tao, Yimin
;
Fang, Li
;
Yang, Yiming
;
Jiang, Hualiang
  |  
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2019/01/08
Alzheimer's disease
Animal proteomics
LC-MS
MS
Huperzine A
p53
Determination of Huperzine A and Huperzine B in Huperzia serrata collected at diffefent collecting times by HPLC
期刊论文
OAI收割
China Journal of Traditional Chinese Medicine and Pharmacy, 2013, 卷号: 28, 期号: 2, 页码: 504-506
作者:
Zhou Xiaolei
;
Yuan Jingquan
;
Wang Shuo
;
Yan Zhigang
;
Feng Shixin
  |  
收藏
  |  
浏览/下载:47/0
  |  
提交时间:2019/01/08
Huperzia serrata
Different season of harvesting
Huperzine A
Huperzine B
HPLC
phaseistudyonthepharmacokineticsandtoleranceofzt1aprodrugofhuperzineaforthetreatmentofalzheimersdisease
期刊论文
OAI收割
actapharmacologicasinica, 2013, 卷号: 34, 期号: 7, 页码: 976
作者:
Jia Jingying
;
Zhao Qianhua
;
Liu Yun
;
Gui Yuzhou
;
Liu Gangyi
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2020/07/01
CHOLINESTERASE INHIBITOR
CHOLINERGIC HYPOTHESIS
PROGRESS
RAT
MEDICINE
VITRO
DRUG
ZT-1
huperzine A
prodrug
AChE inhibitor
drug tolerance
pharmacokinetics
Alzheimer's disease
HPLC法测定不同季节千层塔中石杉碱甲和石杉碱乙含量
期刊论文
OAI收割
中华中医药杂志, 2013, 卷号: 28, 期号: 2, 页码: 504
作者:
周小雷
;
袁经权
;
王硕
;
闫志刚
;
冯世鑫
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2023/06/08
Huperzia serrata
Different season of harvesting
Huperzine A
Huperzine B
HPLC
千层塔
不同季节
石杉碱甲
石杉碱乙
高效液相色谱法
石松生物碱(-)-Huperzine W和(+)-Lycopladine A的不对称全合成
学位论文
OAI收割
硕士: 中国科学院研究生院, 2012
徐弢
收藏
  |  
浏览/下载:44/0
  |  
提交时间:2015/03/23
全合成
Huperzine W
Lycopladine A
Helquist环化
Still偶联
Krhnke吡啶合成
New insights into huperzine A for the treatment of Alzheimer's disease
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2012, 卷号: 33, 期号: 9, 页码: 1170-1175
作者:
Zhang, Hai-yan
  |  
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2019/01/08
Alzheimer's disease
huperzine A
acetylcholinesterase
mitochondrion
controlled release
Huperzine A Alleviates Synaptic Deficits and Modulates Amyloidogenic and Nonamyloidogenic Pathways in APPswe/PS1dE9 Transgenic Mice
期刊论文
OAI收割
JOURNAL OF NEUROSCIENCE RESEARCH, 2012, 卷号: 90, 期号: 2, 页码: 508-517
作者:
Wang, Ying
;
Tang, Xi Can
;
Zhang, Hai Yan
  |  
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2019/01/08
Alzheimer's disease
huperzine A
beta-amyloid
ADAM10
BACE1