中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [8]
昆明植物研究所 [1]
采集方式
OAI收割 [9]
内容类型
期刊论文 [9]
发表日期
2024 [1]
2023 [1]
2022 [1]
2021 [1]
2020 [2]
2015 [1]
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Editorial: Advances in novel drugs and targets for hepatic and gastrointestinal diseases
期刊论文
OAI收割
FRONTIERS IN PHARMACOLOGY, 2024, 卷号: 15, 页码: 4
作者:
Ngowi, Ebenezeri Erasto
;
Gao, Yong
;
Yang, Xiaoying
;
Qiao, Aijun
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2024/02/27
novel drugs
target
liver diseases
gastrointestinal diseases
molecular mechanism
Hepatic Stellate Celland Liver Microbiome-Specific Delivery System for Dihydrotanshinone I to Ameliorate Liver Fibrosis
期刊论文
OAI收割
ACS NANO, 2023, 卷号: 17, 期号: 23, 页码: 23608-23625
作者:
Niu,Xia
;
Meng,Yanan
;
Cui,Jinjin
;
Li,Rui
;
Ding,Xiao
  |  
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2024/07/10
liver fibrosis
dihydrotanshinone I
hepaticstellate cells
vitamin A
cyclodextrin
liver microbiome
STRATEGY
THERAPY
TARGET
NANOPARTICLES
PATHWAY
Bile acid and receptors: biology and drug discovery for nonalcoholic fatty liver disease
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2022, 页码: 17
作者:
Jiao, Ting-ying
;
Ma, Yuan-di
;
Guo, Xiao-zhen
;
Ye, Yun-fei
;
Xie, Cen
  |  
收藏
  |  
浏览/下载:36/0
  |  
提交时间:2022/06/15
bile acids
nonalcoholic fatty liver disease
nonalcoholic steatohepatitis
drug target
Farnesoid X receptor
G protein-coupled bile acid receptor
Discovery of novel ketoxime ether derivatives with potent FXR agonistic activity, oral effectiveness and high liver/blood ratio
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY, 2021, 卷号: 43, 页码: 13
作者:
Tang, Xuehang
  |  
收藏
  |  
浏览/下载:54/0
  |  
提交时间:2021/11/04
FXR agonist
Ketoxime ether
Target genes
Liver
blood ratio
Systemic activation
Research progress on the protective effects of licorice-derived 18 beta-glycyrrhetinic acid against liver injury
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 9
作者:
Wu, Shou-yan
;
Wang, Wen-jie
;
Dou, Jin-hui
;
Gong, Li-kun
  |  
收藏
  |  
浏览/下载:41/0
  |  
提交时间:2020/07/01
18 beta-glycyrrhetic acid
licorice preparation
liver injury
glycyrrhetinic acid target
Liver-Target and Glucose-Responsive Polymersomes toward Mimicking Endogenous Insulin Secretion with Improved Hepatic Glucose Utilization
期刊论文
OAI收割
ADVANCED FUNCTIONAL MATERIALS, 2020, 页码: 15
作者:
Wang, Aohua
;
Fan, Weiwei
;
Yang, Tiantian
;
He, Shufang
;
Yang, Yiwei
  |  
收藏
  |  
浏览/下载:62/0
  |  
提交时间:2020/07/01
glucose responsive
insulin secretion
liver target
oral drug delivery
polymersomes
23benzoylthioureido4567tetrahydrobenzobthiophene3carboxylicacidamelioratesmetabolicdisordersinhighfatdietfedmice
期刊论文
OAI收割
actapharmacologicasinica, 2015, 卷号: 36, 期号: 4, 页码: 483
作者:
Zhang Jin
;
Zhang Lina
;
Chen Dongmei
;
Fu Yanyun
;
Zhang Feng
  |  
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2020/07/01
ACTIVATED PROTEIN-KINASE
ELEMENT-BINDING PROTEIN-1C
INSULIN-RESISTANCE
LIVER-DISEASE
TRANSCRIPTION FACTOR
DIABETES-MELLITUS
HEPATIC STEATOSIS
CULTURED-CELLS
SREBP ACTIVITY
DIRECT TARGET
2-(3-benzoylthioureido)-4,5,6,7-tetrahydrobenzob thiophene-3-carboxylic acid
lipogenesis
SREBP-1c
AMPK
mTOR
hepatic lipid accumulation
obesity
metabolic disorders
DGAT:a new target for prevention and treatment of obesity and diabetes
期刊论文
OAI收割
Chinese Bulletin of Life Sciences, 2010, 卷号: 22, 期号: 2, 页码: 173-178
作者:
YAN Gui-rui
;
ZHANG Xiao-dong
;
ZHU Wei-liang
;
WANG He-yao
  |  
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2019/01/08
DGAT
DGAT
obesity
fatty liver
diabetes
target
The Research Development of Nuclear Receptor LXRalpha
期刊论文
OAI收割
World Sci-Tech R and D, 2003, 卷号: 25, 期号: 6, 页码: 51-54
作者:
Liu Weizhi
;
Ye Fei
;
Yue Liduo
;
Yu Changying
;
Shen Jianhua
  |  
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2019/01/08
liver X receptor (LXR)
atherosclerosis
cholesterol
target genes
lipid metabolism