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浏览/检索结果: 共281条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序作者升序作者降序 Design method for coral gravel limestone rock-like materials and its mechanical performance 期刊论文  OAI收割 CONSTRUCTION AND BUILDING MATERIALS, 2025, 卷号: 477, 页码: 15 作者:  Wang, Qilin;  Liu, Haifeng;  Zhang, Yongtao;  Chen, Peishuai;  Gong, Jianwu   |  收藏  |  浏览/下载：3/0  |  提交时间：2025/06/27 Coral reef limestone  Orthogonal design  CT scanning  Mix proportions  Pore structure characteristics  Stress-strain curve  Pore-throat network   AlphaFold3 versus experimental structures: assessment of the accuracy in ligand-bound G protein-coupled receptors 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2024, 页码: 12 作者:  He, Xin-heng;  Li, Jun-rui;  Shen, Shi-yi;  Xu, H. Eric   |  收藏  |  浏览/下载：16/0  |  提交时间：2025/01/14 AlphaFold  structure-based drug design  artificial intelligence  GPCR  structural biology   Experimental study on the effect of flexible joints of a deep-buried tunnel across an active fault under high in-situ stress conditions 期刊论文  OAI收割 UNDERGROUND SPACE, 2024, 卷号: 19, 页码: 189-207 作者:  Zhang, Jiawei;  Cui, Zhen;  Sheng, Qian;  Zhao, Wanhua;  Song, Liang   |  收藏  |  浏览/下载：6/0  |  提交时间：2025/06/27 Tunnel project  Crossing active fault  High in-situ stress  Segmental structure design  Flexible joint   HSIS-SIF a high-performance hyperspectral imaging spectrometer for Solar-Induced Chlorophyll Fluorescence of vegetation 期刊论文  OAI收割 OPTICS AND LASERS IN ENGINEERING, 2024, 卷号: 180 作者:  Wang, Tao;  Wu, Su;  Zheng, Shanshan;  Feng, Haisheng;  Wen, Jian   |  收藏  |  浏览/下载：15/0  |  提交时间：2024/11/20 SIF  Imaging spectrometer  Prism -grating structure  Optical design  Hyperspectral remote sensing   Discovery of a 1,6-naphthyridin-4-one-based AXL inhibitor with improved pharmacokinetics and enhanced in vivo antitumor efficacy 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 265, 页码: 17 作者:  Lan, Yaohan;  Peng, Xia;  Ji, Yinchun;  Su, Yi;  Duan, Wenhu   |  收藏  |  浏览/下载：33/0  |  提交时间：2024/02/27 AXL inhibitor  In vivo antitumor efficacy  6-Naphthyridin-4-one derivatives  Scaffold hopping  Structure-based drug design   Structure-based development of potent and selective type-II kinase inhibitors of RIPK1 期刊论文  OAI收割 ACTA PHARMACEUTICA SINICA B, 2024, 卷号: 14, 期号: 1, 页码: 319-334 作者:  Qin, Ying;  Li, Dekang;  Qi, Chunting;  Xiang, Huaijiang;  Meng, Huyan   |  收藏  |  浏览/下载：31/0  |  提交时间：2024/03/06 RIPK1  Necroptosis  Type-II kinase inhibitors  Rational design  Lead optimization  Structure-activity relationship  Anti-inflammation  Preclinical drug discovery   Optimization design of optical windows for deep-sea pressure-resistant structures based on transition materials 期刊论文  OAI收割 FRONTIERS IN MARINE SCIENCE, 2023, 卷号: 10, 页码: 13 作者:  Wei, Yucong;  Ma, Guoliang;  Zhang, Hailong;  Zhang, Xiaowei;  Quan, Xiangqian   |  收藏  |  浏览/下载：37/0  |  提交时间：2024/02/06 pressure-resistant structure  optical window design  finite element analysis  mechanical model analysis  optimized design scheme   Structure-based drug discovery of novel fused- pyrazolone carboxamide derivatives as potent and selective AXL inhibitors 期刊论文  OAI收割 ACTA PHARMACEUTICA SINICA B, 2023, 卷号: 13, 期号: 12, 页码: 4918-4933 作者:  Fang, Feifei;  Dai, Yang;  Wang, Hao;  Ji, Yinchun;  Liang, Xuewu   |  收藏  |  浏览/下载：28/0  |  提交时间：2024/01/26 derivatives  Antitumor drug development  Potential AXL inhibitor  Antitumor activity  Structure-based drug design  Fused-pyrazolone carboxamide   Wavy interface enables extra strengthening in an additively manufactured high-entropy alloy with Mortise-Tenon architecture 期刊论文  OAI收割 INTERNATIONAL JOURNAL OF PLASTICITY, 2023, 卷号: 170, 页码: 18 作者:  Bai, Yunjian;  Li, Yadong;  Wang, Yun-jiang;  Zhang, Kun;  Jiang, Quanyu   |  收藏  |  浏览/下载：27/0  |  提交时间：2023/12/18 High entropy alloy  Laminated structure design  Additive manufacturing  Interface strengthening  Local chemical variation   Design and synthesis of 1H-pyrazolo[3,4-d]pyrimidine derivatives as hematopoietic progenitor kinase 1 (HPK1) inhibitors 期刊论文  OAI收割 BIOORGANIC CHEMISTRY, 2023, 卷号: 140, 页码: 18 作者:  Zhang, Junjie;  Li, Yan;  Tang, Haotian;  Zhou, Qianqian;  Tong, Linjiang   |  收藏  |  浏览/下载：27/0  |  提交时间：2023/12/08 Cancer immunotherapy  HPK1  Structure -based design  HPK1 inhibitor