中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [33]
采集方式
OAI收割 [33]
内容类型
期刊论文 [33]
发表日期
2023 [1]
2022 [2]
2020 [2]
2019 [1]
2017 [1]
2016 [2]
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学科主题
Chemistry [3]
Pharmacolo... [3]
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共33条,第1-10条
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专题:上海药物研究所
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A prodrug of the capsid assembly modulator improved druggability and lowing HBsAg and HBeAg for the treatment of chronic hepatitis B
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 257, 页码: 8
作者:
Chen, Wuhong
;
Gong, Ying
;
Long, Guozhang
;
Wang, Xinran
;
Yang, Yurong
  |  
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2023/10/17
HBV
Capsid assembly modulators
Prodrug
Hepatitis B surface antigen
Design, synthesis and biological evaluation of novel dihydrobenzodioxine derivatives as HBV capsid protein inhibitors
期刊论文
OAI收割
BIOORGANIC CHEMISTRY, 2022, 卷号: 128, 页码: 12
作者:
Liu, Linyue
;
Li, Chuanju
;
Xie, Yong
;
Zhang, Lei
;
Chen, Yunfu
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2023/10/17
HBV
Capsid protein inhibitors
Pharmacophore hybrid
Scaffold hopping
HepAD38 cells
Geranyl phenyl ethers from Illicium micranthum and their anti-HBV activity
期刊论文
OAI收割
CHINESE JOURNAL OF NATURAL MEDICINES, 2022, 卷号: 20, 期号: 2, 页码: 139-147
作者:
Liu Yu
;
You Yun-Xia
;
Rao Li
;
He Qian
;
Su Yu
  |  
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2022/06/15
Illicium micranthum
Geranyl phenyl ethers
Spectroscopic data
Anti-HBV activity
Discovery of Phthalazinone Derivatives as Novel Hepatitis B Virus Capsid Inhibitors
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 63, 期号: 15, 页码: 8134-8145
作者:
Chen, Wuhong
;
Liu, Feifei
;
Zhao, Qiliang
;
Ma, Xinna
;
Lu, Dong
  |  
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2020/12/24
Anti-hepatitis B virus activity of swertisin isolated from Iris tectorum Maxim
期刊论文
OAI收割
JOURNAL OF ETHNOPHARMACOLOGY, 2020, 卷号: 257, 页码: 9
作者:
Xu, Hong-Yan
;
Ren, Ji-Hua
;
Su, Yu
;
Ren, Fang
;
Zhou, Yu-Jiao
  |  
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2020/12/24
Iris tectorum Maxim
Swertisin
Hepatitis B virus
HBsAg
HBeAg
Effects of traditional Chinese medicine formula Le-Cao-Shi on hepatitis B: In vivo and in vitro studies
期刊论文
OAI收割
JOURNAL OF ETHNOPHARMACOLOGY, 2019, 卷号: 244, 页码: 10
作者:
Zhao, Qing
;
Ren, Xia
;
Chen, Min
;
Yue, Shi-Jun
;
Zhang, Meng-Qi
  |  
收藏
  |  
浏览/下载:34/0
  |  
提交时间:2020/07/01
Traditional Chinese medicine
Formula Le-Cao-Shi
Hepatitis B virus
Anti-Hepatitis B
Optimization and Synthesis of Pyridazinone Derivatives as Novel Inhibitors of Hepatitis B Virus by Inducing Genome-free Capsid Formation
期刊论文
OAI收割
ACS INFECTIOUS DISEASES, 2017, 卷号: 3, 期号: 3, 页码: 199-205
作者:
Lu, Dong
;
Liu, Feifei
;
Xing, Weiqiang
;
Tong, Xiankun
;
Wang, Lang
  |  
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2019/01/08
pyridazinone
HBV DNA-free capsids
drug-like optimization
SAR study
lead candidate
Inhibition of hepatitis B virus replication by targeting ribonucleotide reductase M2 protein
期刊论文
OAI收割
BIOCHEMICAL PHARMACOLOGY, 2016, 卷号: 103, 页码: 118-128
作者:
Liu, Xia
;
Xu, Zhijian
;
Hou, Chuanwei
;
Wang, Meng
;
Chen, Xinhuan
  |  
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2019/01/08
Hepatitis B virus
Viral genomic DNA and cccDNA synthesis
Human ribonucleotide reductase small subunit M2 (RRM2)
Small molecule compounds
Drug synergism and drug resistance
Effect of a hepatitis B virus inhibitor, NZ-4, on capsid formation
期刊论文
OAI收割
ANTIVIRAL RESEARCH, 2016, 卷号: 125, 页码: 25-33
作者:
Yang, Li
;
Wang, Ya-Juan
;
Chen, Hai Jun
;
Shi, Li-Ping
;
Tong, Xian-Kun
  |  
收藏
  |  
浏览/下载:51/0
  |  
提交时间:2019/01/08
Anti-hepatitis B virus compound
Capsid formation
pgRNA packaging
Arg-rich domain I
Faster-migrating capsid
A coumarin lignanoid from the stems of Kadsura heteroclita
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2015, 卷号: 25, 期号: 7, 页码: 1506-1508
作者:
Su, Wei
;
Zhao, Jianping
;
Yang, Min
;
Yan, Hui-Wen
  |  
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2019/01/08
Coumarin lignoid
Coumarinlignan
Kadsura heteroclita
Anti-HBV activity