机构

• 上海药物研究所 [134]

采集方式

• OAI收割 [134]

内容类型

• 期刊论文 [134]

发表日期

• 2021 [134]

学科主题

筛选

浏览/检索结果: 共134条，第1-10条 帮助 限定条件 发表日期：2021    专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择提交时间升序提交时间降序题名升序题名降序作者升序作者降序发表日期升序发表日期降序 Identification and mechanism of G protein-biased ligands for chemokine receptor CCR1 期刊论文  OAI收割 NATURE CHEMICAL BIOLOGY, 2021, 页码: 24 作者:  Shao, Zhehua;  Shen, Qingya;  Yao, Bingpeng;  Mao, Chunyou;  Chen, Li-Nan   |  收藏  |  浏览/下载：23/0  |  提交时间：2022/06/15 Dual-Channel Fluorescent Probe for the Simultaneous Monitoring of Peroxynitrite and Adenosine-5 '-triphosphate in Cellular Applications 期刊论文  OAI收割 JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2021, 页码: 10 作者:  Wu, Luling;  Liu, Jihong;  Tian, Xue;  Groleau, Robin R.;  Feng, Beidou   |  收藏  |  浏览/下载：37/0  |  提交时间：2022/06/15 Potent and Selective RIPK1 Inhibitors Targeting Dual-Pockets for the Treatment of Systemic Inflammatory Response Syndrome and Sepsis 期刊论文  OAI收割 ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2021, 页码: 6 作者:  Yang, Xiangbo;  Lu, Huimin;  Xie, Hang;  Zhang, Binbin;  Nie, Tianqing   |  收藏  |  浏览/下载：29/0  |  提交时间：2022/01/18 Binding studies  Drug discovery  Necroptosis  RIPK1 inhibitors  Sepsis   A camptothecin-based, albumin-binding prodrug enhances efficacy and safety in vivo 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 226, 页码: 11 作者:  Cheng, Zhiyang;  Huang, Ying;  Shen, Qianqian;  Zhao, Yangrong;  Wang, Lei   |  收藏  |  浏览/下载：32/0  |  提交时间：2021/11/04 Cancer  beta-glucuronidase  Bioconjugation  Albumin  Camptothecin   Site-specific protein modification by 3-n-butylphthalide in primary hepatocytes: Covalent protein adducts diminished by glutathione and N-acetylcysteine 期刊论文  OAI收割 LIFE SCIENCES, 2021, 卷号: 287, 页码: 14 作者:  Xue, Yaru;  Ren, Xuelian;  Zhu, Zhengdan;  Lei, Peng;  Liu, Mengling   |  收藏  |  浏览/下载：49/0  |  提交时间：2022/01/18 3-n-butylphthalide  Hepatotoxicity  Oxidative stresses  Covalent protein modification  Drug-drug interaction   STING inhibitor ameliorates LPS-induced ALI by preventing vascular endothelial cells-mediated immune cells chemotaxis and adhesion 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2021, 页码: 12 作者:  Wu, Bing;  Xu, Meng-meng;  Fan, Chen;  Feng, Chun-lan;  Lu, Qiu-kai   |  收藏  |  浏览/下载：48/0  |  提交时间：2022/01/18 acute lung injury  STING  vascular endothelial cells  inflammatory cytokines  chemokines  chemotaxis   Engineering nanoparticles to overcome the mucus barrier for drug delivery: Design, evaluation and state-of-the-art 期刊论文  OAI收割 Medicine in Drug Discovery, 2021, 卷号: 12, 页码: 100110 作者:  Liu, Chang;  Jiang, Xiaohe;  Gan, Yong;  Yu, Miaorong   |  收藏  |  浏览/下载：16/0  |  提交时间：2024/03/14 Mucus barrier  Mucosal drug delivery  Nanoparticles  Particle tracking experiments  Mucus-penetrating nanoparticles   A homogeneous time-resolved fluorometric energy transfer assay for the binding assessment of FcRn with IgG antibodies 期刊论文  OAI收割 JOURNAL OF IMMUNOLOGICAL METHODS, 2021, 卷号: 499, 页码: 6 作者:  Song, Yakai;  Deng, Xiaojie;  Shi, Wei;  Tang, Feng;  Huang, Wei   |  收藏  |  浏览/下载：40/0  |  提交时间：2022/01/04 FcRn  TR-FRET  mAb  ADC  Pharmacokinetics   High-Throughput Screening Campaign Identified a Potential Small Molecule RXFP3/4 Agonist 期刊论文  OAI收割 MOLECULES, 2021, 卷号: 26, 期号: 24, 页码: 10 作者:  Lin, Guangyao;  Feng, Yang;  Cai, Xiaoqing;  Zhou, Caihong;  Shao, Lijun   |  收藏  |  浏览/下载：30/0  |  提交时间：2022/06/15 RXFP3  RXFP4  high-throughput screening  agonist  WNN0109-C011   Euphornin L promotes lipid clearance by dual regulation of LDLR and PCSK9 期刊论文  OAI收割 EXPERIMENTAL AND THERAPEUTIC MEDICINE, 2021, 卷号: 22, 期号: 6, 页码: 9 作者:  Li, Huihui;  Li, Jun;  Zhang, Xianjing;  Li, Jiaomeng;  Xi, Cong   |  收藏  |  浏览/下载：15/0  |  提交时间：2022/06/15 euphornin L  lipid-lowering activity  low density lipoprotein receptor  proprotein convertase subtilisin  kexin type 9  extracellular signal-regulated kinase protein  secretion