中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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  • 上海药物研究所 [12]
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Proteasome activation: A novel strategy for targeting undruggable intrinsically disordered proteins 期刊论文  OAI收割
BIOORGANIC CHEMISTRY, 2024, 卷号: 145, 页码: 17
作者:  
Yu, Qian;  Wang, Zheng;  Tu, Yutong;  Cao, Yu;  Zhu, Huajian
  |  收藏  |  浏览/下载:0/0  |  提交时间:2024/05/07
From bench to bedside: current development and emerging trend of KRAS-targeted therapy 期刊论文  OAI收割
ACTA PHARMACOLOGICA SINICA, 2023, 页码: 18
作者:  
Chen, Yi;  Liu, Qiu-pei;  Xie, Hua;  Ding, Jian
  |  收藏  |  浏览/下载:33/0  |  提交时间:2024/01/16
Discovery of Novel Long-Chain Alkenyl Diacid Derivatives as ACLY Inhibitors 期刊论文  OAI收割
CHINESE JOURNAL OF CHEMISTRY, 2022, 页码: 8
作者:  
Song, Gao-Lei;  Cao, Lei;  Zhang, Mei;  Yang, Yu-Rou;  Ma, Jie
  |  收藏  |  浏览/下载:27/0  |  提交时间:2022/09/30
Drug target inference by mining transcriptional data using a novel graph convolutional network framework 期刊论文  OAI收割
PROTEIN & CELL, 2021, 页码: 21
作者:  
Zhong, Feisheng;  Wu, Xiaolong;  Yang, Ruirui;  Li, Xutong;  Wang, Dingyan
  |  收藏  |  浏览/下载:27/0  |  提交时间:2021/12/01
Significant Inhibition of Porcine Epidemic Diarrhea Virus In Vitro by Remdesivir, Its Parent Nucleoside and beta-d-N-4-hydroxycytidine 期刊论文  OAI收割
VIROLOGICA SINICA, 2021, 页码: 9
作者:  
Xie, Yuanchao;  Guo, Xiaozhen;  Hu, Tianwen;  Wei, Daibao;  Ma, Xiuli
  |  收藏  |  浏览/下载:34/0  |  提交时间:2021/05/24
DW14006 as a direct AMPK alpha 1 activator improves pathology of AD model mice by regulating microglial phagocytosis and neuroinflammation 期刊论文  OAI收割
BRAIN BEHAVIOR AND IMMUNITY, 2020, 卷号: 90, 页码: 55-69
作者:  
Lv, Jianlu;  Wang, Wei;  Zhu, Xialin;  Xu, Xiaoju;  Yan, Qiuying
  |  收藏  |  浏览/下载:30/0  |  提交时间:2020/12/21
SIRT5 Regulates Brown Adipocyte Differentiation and Browning of Subcutaneous White Adipose Tissue 期刊论文  OAI收割
DIABETES, 2019, 卷号: 68, 期号: 7, 页码: 1449-1461
作者:  
Shuai, Lin;  Zhang, Li-Na;  Li, Bo-Han;  Tang, Chun-Lan;  Wu, Ling-Yan
  |  收藏  |  浏览/下载:20/0  |  提交时间:2020/07/01
Exploration of the hepatoprotective chemical base of an orally administered herbal formulation (YCHT) in normal and CCl4-intoxicated liver injury rats. Part 2: Hepatic disposition in vivo and hepatoprotective activity in vitro 期刊论文  OAI收割
JOURNAL OF ETHNOPHARMACOLOGY, 2019, 卷号: 236, 页码: 161-172
作者:  
Tian, Xiaoting;  Liu, Huan;  Qiao, Shida;  Yin, Hao;  Chen, Mingcang
  |  收藏  |  浏览/下载:9/0  |  提交时间:2020/07/01
Design, synthesis, and structure-activity relationships of novel 4,7,12,12a-tetrahydro-5H-thieno[3 ',2 ':3,4]pyrido[1,2-b]isoquinoline and 5,8,12,12a-tetrahydro-6H-thieno[2 ',3 ': 4,5]pyrido[2,1-a]isoquinoline derivatives as cellular activators of adenosine 5 '-monophosphate-activated protein kinase (AMPK) 期刊论文  OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY, 2018, 卷号: 26, 期号: 8, 页码: 2017-2027
作者:  
Gu, Zhanni;  Wu, Lingyan;  Duan, Yanan;  Wang, Jiang;  Zhou, Shengbin
  |  收藏  |  浏览/下载:39/0  |  提交时间:2019/01/08
Design, synthesis and. biological evaluation of 4,7,12,12a-tetrahydro-5H-thieno[3 ',2 ':3,4]pyrido[1,2-b]isoquinolines as novel adenosine 5 '-monophosphate-activated protein kinase (AMPK) indirect activators for the treatment of type 2 diabetes 期刊论文  OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 140, 页码: 448-464
作者:  
Zhou, Shengbin;  Duan, Yanan;  Wang, Jiang;  Zhang, Jin;  Sun, Haifeng
  |  收藏  |  浏览/下载:34/0  |  提交时间:2019/01/08