中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [600]
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OAI收割 [600]
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期刊论文 [595]
会议论文 [3]
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学位论文 [1]
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2024 [8]
2023 [43]
2022 [30]
2021 [34]
2020 [25]
2019 [45]
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Biochemist... [6]
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Rational design and discovery of novel oxalate-like derivatives as aphid-repellent candidates based on odorant-binding protein 3
期刊论文
OAI收割
JOURNAL OF MOLECULAR STRUCTURE, 2024, 卷号: 1301, 页码: 11
作者:
Zhu, Ziwei
;
Li, Jianing
;
Liu, Chong
;
Li, Huilin
;
Lu, Xingxing
  |  
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2024/04/09
Odorant-binding protein
Oxalate-like derivatives
Rational design
Repellent activity
Behavioural control agents
A robust and validated LC-MS/MS method for the quantification of ramucirumab in rat and human serum using direct enzymatic digestion without immunoassay
期刊论文
OAI收割
JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 2024, 卷号: 1234, 页码: 11
作者:
Huang, Wen-si
;
Li, Wei-qiang
;
Yu, Xiong
;
Xue, Ming-zhen
  |  
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2024/04/09
Anti -gastric cancer monoclonal antibody
Ramucirumab
LC -MS/MS
Method validation
Surrogate peptide
New chromone derivatives bearing thiazolidine-2,4-dione moiety as potent PTP1B inhibitors: Synthesis and biological activity evaluation
期刊论文
OAI收割
BIOORGANIC CHEMISTRY, 2024, 卷号: 143, 页码: 9
作者:
Zheng, Yingying
;
Lu, Li
;
Li, Mengyue
;
Xu, Dehua
;
Zhang, Laishun
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2024/01/26
Chromone
Thiazolidine-2
4-dione
Protein tyrosine phosphatase 1B
Inhibitors
Structure-based design of potent FABP4 inhibitors with high selectivity against FABP3
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 264, 页码: 10
作者:
Chen, Guofeng
;
Xie, Hang
;
Liu, Jiayuan
;
Shao, Qiang
;
Li, Minjun
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2024/01/26
Methyl substitution
Selectivity
FABP4 inhibitor
Anti-inflammation
Metabolic stability
Benzothiozinone derivatives with anti-tubercular Activity-Further side chain investigation
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 264, 页码: 11
作者:
Wu, Xiaomei
;
Wang, Wenxin
;
Stelitano, Giovanni
;
Riabova, Olga
;
Wang, Bin
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2024/01/26
Anti -tubercular activity
DprE1 inhibitor
Benzothiazinone derivatives
Structure activity relationship
Design and process study of chiral separation of (2
S
,4
S
)-1-(
tert
-butoxy carbonyl)-4-(methoxymethyl) pyrrolidine-2-carboxylic acid for green manufacturing
期刊论文
OAI收割
GREEN CHEMISTRY, 2024, 页码: 11
作者:
Ge, Shuwang
;
Fu, Mingwei
;
Gu, Dihai
;
Wei, Lai
;
Qian, Kun
  |  
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2024/02/27
Discovery and optimization of thieno[3,2-d]pyrimidine derivatives as highly selective inhibitors of cyclin-dependent kinase 7
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 263, 页码: 21
作者:
Zhang, Hongjin
;
Lin, Guohao
;
Jia, Suyun
;
Zhang, Ying
;
Wu, Jianbo
  |  
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2024/01/26
Thieno[3
d ]pyrimidine derivative
Cyclin-dependent kinase 7
Small molecule inhibitor
Kinome selectivity
Triple negative breast cancer
Dimeric cation-cation aggregates stabilized by 2Ch-2N chalcogen bonds: Crystallographic and theoretical evidences
期刊论文
OAI收割
CHEMICAL PHYSICS, 2024, 卷号: 576, 页码: 10
作者:
Liu, Na
;
Han, Zijian
;
Lu, Yunxiang
;
Xu, Zhijian
;
Zhu, Weiliang
  |  
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2023/12/11
2Ch-2N chalcogen bonds
Homocations
Solvents
Evidences
Targeting ST8SIA6-AS1 counteracts KRAS
G12C
inhibitor resistance through abolishing the reciprocal activation of PLK1/c-Myc signaling
期刊论文
OAI收割
EXPERIMENTAL HEMATOLOGY & ONCOLOGY, 2023, 卷号: 12, 期号: 1, 页码: 22
作者:
Wang, Yafang
;
Yao, Mingyue
;
Li, Cheng
  |  
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2024/01/26
KRAS(G12C)
c-Myc
PLK1
LncRNA
ST8SIA6-AS1
Drug resistance
Ginsenoside Rg3 endows liposomes with prolonged blood circulation and reduced accelerated blood clearance
期刊论文
OAI收割
JOURNAL OF CONTROLLED RELEASE, 2023, 卷号: 364, 页码: 23-36
作者:
Xia, Jiaxuan
;
Chen, Chen
;
Dong, Meichen
;
Zhu, Ying
;
Wang, Anni
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2024/01/16
Ginsenoside Rg3
Liposomes
Polyethylene glycol
Long circulation
Accelerated blood clearance (ABC)
IgM antibody
Complement activation