中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
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上海药物研究所 [58]
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期刊论文 [127]
学位论文 [4]
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Effects of exposure to nanoplastics on the gill of mussels
Mytilus
galloprovincialis:
An integrated perspective from multiple biomarkers
期刊论文
OAI收割
MARINE ENVIRONMENTAL RESEARCH, 2023, 卷号: 191, 页码: 8
作者:
Wang, Xin
;
Shao, Shengyuan
;
Zhang, Tianyu
;
Zhang, Qianqian
;
Yang, Dinglong
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2023/11/15
Nanoplastics
Nanotoxicology
Biomarkers
Invertebrates
Ecotoxicology
Water-soluble non-conjugated polymer dots with strong green fluorescence for sensitive detection of organophosphate pesticides
期刊论文
OAI收割
ANALYTICA CHIMICA ACTA, 2022, 卷号: 1206, 页码: 9
作者:
  |  
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2022/08/16
Water-soluble polymer dots
MnO2 nanosheets
Fluorimetric detection
Catalysis inhibition
Organophosphate pesticides
Novel inhibitors of AChE and A0 aggregation with neuroprotective properties as lead compounds for the treatment of Alzheimer's disease
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 235, 页码: 22
作者:
Liu, Yulin
;
Uras, Giuseppe
;
Onuwaje, Itse
;
Li, Wenlong
;
Yao, Hong
  |  
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2022/08/16
Alzheimer's disease
Donepezil
Sulfone group
AChE inhibitor
Inhibiting A 0 aggregation
Neuroprotection
Design, synthesis, in vitro evaluation of a new pyrrolo[1,2-a]thiazolo[5,4-d]pyrimidinone derivatives as cholinesterase inhibitors against Alzheimer's disease
期刊论文
OAI收割
JOURNAL OF HETEROCYCLIC CHEMISTRY, 2022, 页码: 16
作者:
Zeng, Yan
;
Nie, Lifei
;
Liu, Liu
;
Niu, Chao
;
Li, Yi
  |  
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2022/06/15
The novel therapeutic strategy of vilazodone-donepezil chimeras as potent triple-target ligands for the potential treatment of Alzheimer's disease with comorbid depression
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 229, 页码: 22
作者:
Li, Xiaokang
;
Li, Jinwen
;
Huang, Yunyuan
;
Gong, Qi
;
Fu, Yan
  |  
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2022/06/15
Alzheimer's disease
Depression
Comorbidity
Multi-target-directed ligands
Rational design of a near-infrared fluorescence probe for highly selective sensing butyrylcholinesterase (BChE) and its bioimaging applications in living cell
期刊论文
OAI收割
TALANTA, 2020, 卷号: 219, 页码: 10
作者:
Ma, Jianlong
;
Lu, Xiaofeng
;
Zhai, Honglin
;
Li, Qiang
;
Qiao, Li
  |  
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2021/12/15
Fluorescent probe
Rational design
Highly selective
Butyrylcholinesterase
代谢组学在中药质量标志物和药物代谢研究中的应用
学位论文
OAI收割
2020
作者:
王义坤
  |  
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2023/11/02
Discovery and Biological Evaluation of New Selective Acetylcholinesterase Inhibitors with Anti-A beta Aggregation Activity through Molecular Docking-Based Virtual Screening
期刊论文
OAI收割
CHEMICAL & PHARMACEUTICAL BULLETIN, 2020, 卷号: 68, 期号: 2, 页码: 161-166
作者:
Liu, Guangpu
;
Jiao, Yang
;
Lin, Yongqiang
;
Hao, Haifang
;
Dou, Yanli
  |  
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2020/07/01
selective acetylcholinesterase inhibitor
amyloid beta aggregation
neuroprotectant
molecular docking
molecular dynamics simulation
Two new prenylated C-6-C-3 compounds from Illicium micranthum Dunn
期刊论文
OAI收割
NATURAL PRODUCT RESEARCH, 2020, 卷号: 34, 期号: 3, 页码: 425-428
作者:
Liu, Lu
;
Lv, Xiao-Man
;
Hua, Tian
;
Khan, Afsar
;
Huang, Xiao-Bing
  |  
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2020/03/18
Illicium micranthum
prenylated C6-C3 compounds
sesquiterpene lactone
acetylcholinesterase
Applanaic acids A-C, three new highly oxygenated lanostane triterpenoids from the fruiting bodies of Ganoderma applanatum.
期刊论文
OAI收割
Natural product research, 2020, 卷号: 34, 期号: 4, 页码: 1-7
作者:
Chen, Yu
;
Gao, Jie
;
Chen, Qibin
;
Liu, Wei
;
Qi, Yanru
  |  
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2020/05/06
AChE
Ganoderma applanatum
applanaic acid
lanostane triterpenoid