中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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上海药物研究所 [32]
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期刊论文 [59]
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2023 [5]
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Epigenetic-based combination therapy and liposomal codelivery overcomes osimertinib-resistant NSCLC via repolarizing tumor-associated macrophages
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2023, 页码: 12
作者:
Lin, Ting-ting
;
Xiong, Wei
;
Chen, Gui-hua
;
He, Yang
;
Long, Li
  |  
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2024/01/26
osimertinib resistance
targeted drug delivery
liposomes
panobinostat
tumor-associated macrophage
combination therapy
Hedgehog pathway orchestrates the interplay of histone modifications and tailors combination epigenetic therapies in breast cancer
期刊论文
OAI收割
ACTA PHARMACEUTICA SINICA B, 2023, 卷号: 13, 期号: 6, 页码: 2601-2612
作者:
Wang, Xiaomin
;
Xu, Jun
;
Sun, Yiming
;
Cao, Siyuwei
;
Zeng, Hanlin
  |  
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2023/10/17
HDAC inhibitors
Drug resistance
Histone methylation
Histone acetylation
Epigenetic interplay
Hedgehog pathway
ZIC1
LIFR
Combination therapy
Breast cancer
Phosphorylation of PHF2 by AMPK releases the repressive H3K9me2 and inhibits cancer metastasis
期刊论文
OAI收割
Signal Transduction and Targeted Therapy, 2023, 卷号: 8, 期号: 4, 页码: 1857-1873
作者:
Dong, Ying
;
Hu, Hao
;
Zhang, Xuan
;
Zhang, Yunkai
;
Sun, Xin
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2024/03/27
Design, synthesis, and biological evaluation of BRD4 degraders
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY, 2023, 卷号: 78, 页码: 12
作者:
Ding, Mengyuan
;
Shao, Yingying
;
Sun, Danwen
;
Meng, Suorina
;
Zang, Yi
  |  
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2023/04/10
PROTAC
BRD4 degradation
Leukemia
Multiple myeloma
Pulmonary fibrosis
Hyperactive DNA Cutting for Unbiased UHPLC-MS/MS Quantification of Epigenetic DNA Marks by Engineering DNase I Mutants
期刊论文
OAI收割
ANALYTICAL CHEMISTRY, 2023, 页码: 1-7
作者:
Song, Xingrui
;
Song, Xinyue
;
Lai, Weiyi
;
Wang, Hailin
  |  
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2023/02/06
Regulation of CCL2 by EZH2 affects tumor-associated macrophages polarization and infiltration in breast cancer
期刊论文
OAI收割
CELL DEATH & DISEASE, 2022, 卷号: 13, 期号: 8, 页码: 15
作者:
Wang, Ya-fang
;
Yu, Lei
;
Hu, Zong-long
;
Fang, Yan-fen
;
Shen, Yan-yan
  |  
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2022/11/11
HMGN4 plays a key role in STAT3-mediated oncogenesis of triple-negative breast cancer
期刊论文
OAI收割
CARCINOGENESIS, 2022, 页码: 11
作者:
Mou, Jiahui
;
Xu, Xiaoding
;
Wang, Feifei
;
Kong, Weiwen
;
Chen, Jing
  |  
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2022/09/30
Effects of N-6-Methyladenosine Modification on Cancer Progression: Molecular Mechanisms and Cancer Therapy
期刊论文
OAI收割
FRONTIERS IN ONCOLOGY, 2022, 卷号: 12
作者:
Zhu, Yong-fu
;
Wang, Shu-Jie
;
Zhou, Jie
;
Sun, Ye-han
;
Chen, You-mou
  |  
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2022/12/23
RNA modifications
N6-methyladenosine
female malignancies
molecular mechanisms
immunotherapy
An Integrative Proteome-Based Pharmacologic Characterization and Therapeutic Strategy Exploration of SAHA in Solid Malignancies br
期刊论文
OAI收割
JOURNAL OF PROTEOME RESEARCH, 2022, 卷号: 21, 期号: 4, 页码: 953-964
作者:
Liu, Quan
;
Hao, Bingbing
;
Zhang, Mingya
;
Liu, Zhiwei
;
Huang, Yuqi
  |  
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2022/06/15
proteomics
SAHA
2-deoxy-D-glucose
new combination strategy
Remodeling "cold" tumor immune microenvironment via epigenetic-based therapy using targeted liposomes with in situ formed albumin corona
期刊论文
OAI收割
ACTA PHARMACEUTICA SINICA B, 2022, 卷号: 12, 期号: 4, 页码: 2057-2073
作者:
He, Yang
;
Fang, Yuefei
;
Zhang, Meng
;
Zhao, Yuge
;
Tu, Bin
  |  
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2022/08/16
Tumor immune microenvironment
Tumor-associated macrophage
Epigenetic therapy
Immune checkpoint
Angiogenesis
Panobinostat
JQ1
Liposome