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浏览/检索结果: 共941条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择提交时间升序提交时间降序发表日期升序发表日期降序题名升序题名降序作者升序作者降序 JC-010a, a novel selective SHP2 allosteric inhibitor, overcomes RTK/non-RTK-mediated drug resistance in multiple oncogene-addicted cancers 期刊论文  OAI收割 CANCER LETTERS, 2024, 卷号: 582, 页码: 15 作者:  Lu, Xuxiu;  Yu, Rilei;  Li, Zhen;  Yang, Mengke;  Dai, Jiajia   |  收藏  |  浏览/下载：13/0  |  提交时间：2024/04/07 Acquired resistance  Cancer  NSCLC  JC-010a  SHP2   Discovery of a potent and selective covalent threonine tyrosine kinase (TTK) inhibitor 期刊论文  OAI收割 BIOORGANIC CHEMISTRY, 2024, 卷号: 143, 页码: 16 作者:  Sun, Yaoliang;  Chen, Zhiwen;  Liu, Guobin;  Chen, Xiaoai;  Shi, Zihan   |  收藏  |  浏览/下载：9/0  |  提交时间：2024/03/25 Inhibitor  Cancer  Threonine tyrosine kinase (TTK)  Covalent   Paralichthys olivaceus MLKL-mediated necroptosis is activated by RIPK1/3 and involved in anti-microbial immunity 期刊论文  OAI收割 FRONTIERS IN IMMUNOLOGY, 2024, 卷号: 15, 页码: 11 作者:  Hao, Kangwei;  Xu, Hang;  Jiang, Shuai;  Sun, Li   |  收藏  |  浏览/下载：12/0  |  提交时间：2024/04/07 Paralichthys olivaceus  necroptosis  RIPK1  RIPK3  MLKL  immune defense   Structure-based optimization of indoline-containing compounds as second generation inhibitors of NF-KB-inducing kinase (NIK) 期刊论文  OAI收割 JOURNAL OF MOLECULAR STRUCTURE, 2024, 卷号: 1295, 页码: 19 作者:  Cheng, Jing;  Yan, Ziqin;  Li, Xinzhi;  Liu, Chen;  Tong, Linjiang   |  收藏  |  浏览/下载：8/0  |  提交时间：2023/12/08 Kinase inhibitor  NIK  NF-KB2  Indoline  COT  Cytotoxicity   Tumor-Associated Macrophage Targeting of Nanomedicines in Cancer Therapy 期刊论文  OAI收割 PHARMACEUTICS, 2024, 卷号: 16, 期号: 1, 页码: 28 作者:  Kang, Xuejia;  Huang, Yongzhuo;  Wang, Huiyuan;  Jadhav, Sanika;  Yue, Zongliang   |  收藏  |  浏览/下载：6/0  |  提交时间：2024/02/27 tumor-associated macrophage  suppressive immune environment  tumor proliferation and metastasis  nanomedicine  targeted delivery systems   Design and synthesis of 1H-pyrazolo[3,4-d]pyrimidine derivatives as hematopoietic progenitor kinase 1 (HPK1) inhibitors 期刊论文  OAI收割 BIOORGANIC CHEMISTRY, 2023, 卷号: 140, 页码: 18 作者:  Zhang, Junjie;  Li, Yan;  Tang, Haotian;  Zhou, Qianqian;  Tong, Linjiang   |  收藏  |  浏览/下载：8/0  |  提交时间：2023/12/08 Cancer immunotherapy  HPK1  Structure -based design  HPK1 inhibitor   Chemical Inhibitors Targeting the Oncogenic m6A Modifying Proteins 期刊论文  OAI收割 ACCOUNTS OF CHEMICAL RESEARCH, 2023, 卷号: 56, 期号: 21, 页码: 3010-3022 作者:  Huang, Yue;  Xia, Wenyang;  Dong, Ze;  Yang, Cai-Guang   |  收藏  |  浏览/下载：7/0  |  提交时间：2023/12/11 Deciphering the functional landscape of phosphosites with deep neural network 期刊论文  OAI收割 CELL REPORTS, 2023, 卷号: 42, 期号: 9, 页码: 23 作者:  Liang, Zhongjie;  Liu, Tonghai;  Li, Qi;  Zhang, Guangyu;  Zhang, Bei   |  收藏  |  浏览/下载：9/0  |  提交时间：2023/12/08 Comparative proteomic and phosphoproteomic analysis reveals differential heat response mechanism in two congeneric oyster species 期刊论文  OAI收割 ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY, 2023, 卷号: 263, 页码: 19 作者:  Wang, Chaogang;  Du, Mingyang;  Jiang, Zhuxiang;  Cong, Rihao;  Wang, Wei   |  收藏  |  浏览/下载：6/0  |  提交时间：2023/12/13 Heat stress  Oysters  Crassostrea angulata  Crassostrea gigas  Phosphorylation   Predicting and overcoming resistance to CDK9 inhibitors for cancer therapy 期刊论文  OAI收割 ACTA PHARMACEUTICA SINICA B, 2023, 卷号: 13 作者:  Hua, Chen;  Shena, Lijuan;  Zoua, Fengming;  Wua, Yun;  Wanga, Beilei   |  收藏  |  浏览/下载：11/0  |  提交时间：2023/11/10 Acquired resistance mutations  CDK9 inhibitors  Transcription  Single nucleotide polymorphisms  BAY1251152