中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [13]
大连化学物理研究所 [9]
南海海洋研究所 [2]
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期刊论文 [24]
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Design, synthesis and biological evaluation of chalcone derivatives as potent and orally active hCYP3A4 inhibitors
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2023, 卷号: 95, 页码: 9
作者:
Lu, Shiwei
;
Zhang, Feng
;
Gong, Jiahao
;
Huang, Jian
;
Zhu, Guanghao
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2023/12/08
Cytochrome P450 3A4 (CYP3A4)
Inhibitors
Isoquinoline chalcones
Orally active
Enabling Heterologous Synthesis of Lupulones in the Yeast Saccharomyces cerevisiae
期刊论文
OAI收割
APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY, 2019, 卷号: 188, 期号: 3, 页码: 787-797
作者:
Guo, Xiaojia
;
Shen, Hongwei
;
Liu, Yuxue
;
Wang, Qian
;
Wang, Xueying
  |  
收藏
  |  
浏览/下载:65/0
  |  
提交时间:2019/12/02
Chemical genetics
Lupulones
Metabolic engineering
Mevalonate pathway
Saccharomyces cerevisiae
Pharmacokinetic Drug Interactions of Apatinib With Rifampin and Itraconazole
期刊论文
OAI收割
JOURNAL OF CLINICAL PHARMACOLOGY, 2018, 卷号: 58, 期号: 3, 页码: 347-356
作者:
Liu, Xiaoyun
;
Zhang, Yifan
;
Chen, Qian
;
Zhan, Yan
;
Wang, Quanren
  |  
收藏
  |  
浏览/下载:49/0
  |  
提交时间:2019/01/08
apatinib
rifampin
itraconazole
drug-drug interaction
pharmacokinetics
Impact of curcumin on the pharmacokinetics of rosuvastatin in rats and dogs based on the conjugated metabolites
期刊论文
OAI收割
XENOBIOTICA, 2017, 卷号: 47, 期号: 3, 页码: 267-275
作者:
Zhou, Xin
;
Zhang, Fangrong
;
Chen, Chang
;
Guo, Zitao
;
Liu, Jia
  |  
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2019/01/08
Curcumin
drug-drug interaction
OAT
OATP
rosuvastatin
transporter
SQ109, a New Drug Lead for Chagas Disease
期刊论文
OAI收割
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2015, 卷号: 59, 期号: 4, 页码: 1950-1961
作者:
Veiga-Santos, Phercyles
;
Li, Kai
;
Lameira, Lilianne
;
Ulisses de Carvalho, Tecia Maria
;
Huang, Guozhong
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2016/06/23
Effects of Rifampin and Ketoconazole on Pharmacokinetics of Morinidazole in Healthy Chinese Subjects
期刊论文
OAI收割
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2014, 卷号: 58, 期号: 10, 页码: 5987-5993
作者:
Pang, Xiaoyan
;
Zhang, Yifan
;
Gao, Ruina
;
Zhong, Kan
;
Zhong, Dafang
  |  
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2019/01/08
Hepatic cytochrome P450s play a major role in monocrotaline-induced renal toxicity in mice
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2014, 卷号: 35, 期号: 2, 页码: 292-300
作者:
Yao, Jun
;
Li, Cheng-gang
;
Gong, Li-kun
;
Feng, Chen-chen
;
Li, Chun-zhu
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2019/01/08
monocrotaline
pyrrolizidine alkaloid
hepatic cytochrome P450s
ketoconazole
metabolic activation
hepatic toxicity
renal toxicity
hepaticcytochromep450splayamajorroleinmonocrotalineinducedrenaltoxicityinmice
期刊论文
OAI收割
actapharmacologicasinica, 2014, 卷号: 35, 期号: 2, 页码: 292
作者:
Yao Jun
;
Li Chenggang
;
Gong Likun
;
Feng Chenchen
;
Li Chunzhu
  |  
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2020/07/01
monocrotaline
pyrrolizidine alkaloid
hepatic cytochrome P450s
ketoconazole
metabolic activation
hepatic toxicity
renal toxicity
Effects of ketoconazole and rifampicin on the pharmacokinetics of GLS4, a novel anti-hepatitis B virus compound, in dogs
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2013, 卷号: 34, 期号: 11, 页码: 1420-1426
作者:
Zhou, Xin
;
Gao, Zhi-wei
;
Meng, Jian
;
Chen, Xiao-yan
;
Zhong, Da-fang
  |  
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2019/01/08
GLS4
ketoconazole
rifampicin
CYP3A
drug-drug interaction
hepatitis B virus
Human cytochrome P450 3A4 and a carbon nanofiber modified film electrode as a platform for the simple evaluation of drug metabolism and inhibition reactions
期刊论文
OAI收割
analyst, 2013, 卷号: 138, 期号: 21, 页码: 6463-6468
Xue Q
;
Kato D
;
Kamata T
;
Guo QH
;
You TY
;
Niwa O
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2014/04/16
ELECTROCHEMICALLY-DRIVEN
GLUCOSE BIOSENSOR
CYP3A4
NANOPARTICLES
PERFORMANCE
COMPOSITES
MICROSOMES
NANOTUBES
OXIDASE