中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
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上海药物研究所 [149]
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大连化学物理研究所 [10]
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期刊论文 [196]
学位论文 [5]
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Discovery and exploration of novel somatostatin receptor subtype 5 (SSTR5) antagonists for the treatment of cholesterol gallstones
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 264, 页码: 16
作者:
Han, Fanghui
;
Zhao, Tingting
;
Zhang, Yanglong
;
Yun, Ying
;
Xu, Yuanyuan
  |  
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2024/02/19
SSTR5 antagonist
Gallbladder emptying
Cholesterol gallstones
Development and validation of a sensitive liquid chromatography-tandem mass spectrometry method for the assay of 12 substances in rat plasma and its application to rat pharmacokinetics of
Epimedium
and
Psoraleae Fructus
herb pair after oral administration
期刊论文
OAI收割
JOURNAL OF SEPARATION SCIENCE, 2024, 卷号: 47, 期号: 1, 页码: 17
作者:
Wang, Linwei
;
Yin, Xiaoying
;
Liu, Huan
;
Wang, Yangyang
;
Li, Zhixiong
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2024/02/27
compatibility behaviors
Epimedium
LC-MS/MS
pharmacokinetics
Psoraleae Fructus
Absorption, Distribution, Metabolism, and Excretion of [
14
C]BS1801, a Selenium-Containing Drug Candidate, in Rats
期刊论文
OAI收割
MOLECULES, 2023, 卷号: 28, 期号: 24, 页码: 16
作者:
Yang, Cheng
;
Xue, Mingzhen
;
He, Yifei
;
Yin, Hanwei
;
Yang, Chen
  |  
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2024/01/26
[C-14]BS1801
BS1801 (butaselen)
tissue distribution
metabolism
mass balance
selenium
Cyclodextrin MOFs modified dry powder inhalers quadruple bioavailability of luteolin to ameliorate fibrosing interstitial lung disease
期刊论文
OAI收割
INTERNATIONAL JOURNAL OF PHARMACEUTICS, 2023, 卷号: 645, 页码: 9
作者:
Ren, Xiaohong
;
Yang, Ting
;
Zhang, Kaikai
;
Liu, Yujie
;
Wang, Caifen
  |  
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2023/12/08
Fibrosing interstitial lung disease
Luteolin
Cyclodextrin metal -organic frameworks
Dry powder inhalers
Loratadine oral bioavailability enhancement via solid dispersion loaded oro-dispersible films: Formulation, characterization and pharmacokinetics
期刊论文
OAI收割
COLLOIDS AND SURFACES B-BIOINTERFACES, 2023, 卷号: 230
作者:
Islam, Nayyer
;
Khan, Naveed Ullah
;
Razzaq, Anam
;
Menaa, Farid
;
Khan, Zaheer Ullah
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2023/11/17
Loratadine
Solid dispersion
Oro-dispersible film
Bioavailability
Urticaria
Enhancing the oral bioavailability of poorly water-soluble amisupiride with solid nanodispersion
期刊论文
OAI收割
JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY, 2023, 卷号: 86, 页码: 6
作者:
Zhang, Xinyue
;
Li, Jie
;
Rong, Rong
;
Wang, Dangge
;
Wang, Donghai
  |  
收藏
  |  
浏览/下载:65/0
  |  
提交时间:2023/10/17
Solid dispersion
Oral bioavailability
Amisupiride
Nanoparticle
Poorly water-soluble drugs
TGR5 agonist inhibits intestinal epithelial cell apoptosis via cAMP/PKA/c-FLIP/JNK signaling pathway and ameliorates dextran sulfate sodium-induced ulcerative colitis
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2023, 卷号: 44, 期号: 8, 页码: 1649-1664
作者:
Yang, Wen-ji
;
Han, Fang-hui
;
Gu, Yi-pei
;
Qu, Hui
;
Liu, Jia
  |  
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2024/03/27
TGR5 agonist
ulcerative colitis
intestinal epithelial cell
apoptosis
cAMP
PKA signaling pathway
c-FLIP
Highly efficient pulmonary delivery of levo-tetrahydropalmatine using gamma-cyclodextrin metal-organic framework as a drug delivery platform
期刊论文
OAI收割
JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY, 2023, 卷号: 82, 页码: 12
作者:
Nie, Qin
;
Wang, Caifen
;
Xu, Huipeng
;
Mittal, Priyanka
;
Naeem, Abid
  |  
收藏
  |  
浏览/下载:59/0
  |  
提交时间:2023/10/17
Levo-tetrahydropalmatine
Pulmonary delivery
gamma-Cyclodextrin metal-organic frameworks
Dry powder inhaler
Bioavailability
Rucaparib cocrystal: Improved solubility and bioavailability over camsylate
期刊论文
OAI收割
INTERNATIONAL JOURNAL OF PHARMACEUTICS, 2023, 卷号: 631, 页码: 10
作者:
Xia, Mengyuan
;
Jiang, Yihua
;
Cheng, Yinxiang
;
Dai, Wenjuan
;
Rong, Xiaoyi
  |  
收藏
  |  
浏览/下载:63/0
  |  
提交时间:2023/04/10
Rucaparib
Cocrystal
Solubility
Dissolution
Bioavailability
Limosilactobacillus reuteri and caffeoylquinic acid synergistically promote adipose browning and ameliorate obesity-associated disorders
期刊论文
OAI收割
MICROBIOME, 2022, 卷号: 10, 期号: 1, 页码: 22
作者:
Liu, Yameng
;
Zhong, Xianchun
;
Lin, Suqin
;
Xu, Hualing
;
Liang, Xinyu
  |  
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2023/04/10
Obesity
Prebiotic
Probiotics
Short-chain fatty acids
Propionate
Thermogenesis
Browning