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浏览/检索结果: 共191条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择提交时间升序提交时间降序发表日期升序发表日期降序题名升序题名降序作者升序作者降序 Exploring the mechanism of the PTP1B inhibitors by molecular dynamics and experimental study 期刊论文  OAI收割 JOURNAL OF MOLECULAR GRAPHICS & MODELLING, 2023, 卷号: 125, 页码: 12 作者:  Zhao, Tian-Tian;  Hu, Hao-Jie;  Gao, Li-Xin;  Zhou, Yu-Bo;  Zhu, Yun-Long   |  收藏  |  浏览/下载：11/0  |  提交时间：2023/10/17 Protein tyrosine phosphatases inhibitors  PTP1B inhibitors  Mechanism study  Molecular dynamics   Structure-Based Ligand Discovery Targeting the Transmembrane Domain of Frizzled Receptor FZD7 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2023, 页码: 14 作者:  Li, Cuixia;  Wu, Yiran;  Wang, Wenli;  Xu, Lu;  Zhou, Yan   |  收藏  |  浏览/下载：14/0  |  提交时间：2023/10/17 GPCR activation and GRK2 assembly by a biased intracellular agonist 期刊论文  OAI收割 NATURE, 2023, 页码: 27 作者:  Duan, Jia;  Liu, Heng;  Zhao, Fenghui;  Yuan, Qingning;  Ji, Yujie   |  收藏  |  浏览/下载：12/0  |  提交时间：2023/10/17 Zebrafish (Danio rerio) TR beta- and TTR-based electrochemical biosensors: Construction and application for the evaluation of thyroid-disrupting activity of bisphenols 期刊论文  OAI收割 ENVIRONMENTAL POLLUTION, 2023, 卷号: 330, 页码: 9 作者:  Li, Yuejiao;  Zhang, Zhenzhong;  Wang, Jun;  Shan, Yeqi;  Tian, Hua   |  收藏  |  浏览/下载：6/0  |  提交时间：2023/12/07 Thyroid-disrupting chemicals  Thyroid hormone receptor beta  Transthyretin  In vitro screening Assay  Electrochemical biosensor   Two New Alkaloids and a New Butenolide Derivative from the Beibu Gulf Sponge-Derived Fungus Penicillium sp. SCSIO 41413 期刊论文  OAI收割 MARINE DRUGS, 2023, 卷号: 21, 期号: 1, 页码: 11 作者:  Ye, Yuxiu;  Liang, Jiaqi;  She, Jianglian;  Lin, Xiuping;  Wang, Junfeng   |  收藏  |  浏览/下载：17/0  |  提交时间：2023/04/10 sponge-derived fungus  Penicillium sp  PI3K  NF-kappa B   Deffini: A family-specific deep neural network model for structure-based virtual screening 期刊论文  OAI收割 COMPUTERS IN BIOLOGY AND MEDICINE, 2022, 卷号: 151, 页码: 8 作者:  Zhou, Dixin;  Liu, Fei;  Zheng, Yiwen;  Hu, Liangjian;  Huang, Tao   |  收藏  |  浏览/下载：9/0  |  提交时间：2023/04/10 Virtual screening  Protein family -specific model  Structure -based  Convolutional neural network  Drug discovery   An optimization algorithm for conformer generation based on the bond contribution ranking 期刊论文  OAI收割 COMPUTATIONAL BIOLOGY AND CHEMISTRY, 2022, 卷号: 100, 页码: 107751 作者:  Zhang, Ziheng;  Zhang, Kai;  Liu, Zhihui;  Zhao, Jialei;  Wang, Jing   |  收藏  |  浏览/下载：13/0  |  提交时间：2024/03/21 Conformer generation  Bond contribution rank  Systematic sampling  Torsion angle   DeepBindBC: A practical deep learning method for identifying native-like protein-ligand complexes in virtual screening 期刊论文  OAI收割 METHODS, 2022, 卷号: 205, 页码: 247-262 作者:  Zhang, Haiping;  Zhang, Tingting;  Saravanan, Konda Mani;  Liao, Linbu;  Wu, Hao   |  收藏  |  浏览/下载：7/0  |  提交时间：2023/07/12 Native like protein-ligand  Drug virtual screening  ResNet  Deep learning  Human pancreatic alpha amylase inhibitor   2,2 ',4,4 '-Tetrabromodiphenyl Ether (PBDE 47) Selectively Stimulates Proatherogenic PPAR gamma Signatures in Human THP-1 Macrophages to Contribute to Foam Cell Formation 期刊论文  OAI收割 CHEMICAL RESEARCH IN TOXICOLOGY, 2022, 卷号: 35, 期号: 6, 页码: 1023-1035 作者:  Ren, Qidong;  Xie, Xinni;  Zhao, Chuanfang;  Wen, Qing;  Pan, Ruiying   |  收藏  |  浏览/下载：15/0  |  提交时间：2022/11/08 ACTIVATED-RECEPTOR-GAMMA  BROMINATED FLAME RETARDANTS  ACID-BINDING PROTEIN  GENE-EXPRESSION  LIGAND-BINDING  DIPHENYL ETHERS  INDOOR DUST  EXPOSURE  CD36  ACCUMULATION   Gremlin1 is a therapeutically targetable FGFR1 ligand that regulates lineage plasticity and castration resistance in prostate cancer 期刊论文  OAI收割 NATURE CANCER, 2022, 卷号: 3, 期号: 5, 页码: 565-+ 作者:  Cheng, Chaping;  Wang, Jinming;  Xu, Penghui;  Zhang, Kai;  Xin, Zhixiang   |  收藏  |  浏览/下载：34/0  |  提交时间：2022/08/16