中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
生态环境研究中心 [15]
水生生物研究所 [9]
上海药物研究所 [5]
上海营养与健康研究所 [4]
上海生物化学与细胞生... [3]
南海海洋研究所 [1]
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OAI收割 [40]
内容类型
期刊论文 [39]
学位论文 [1]
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2023 [2]
2022 [3]
2021 [3]
2020 [5]
2019 [2]
2018 [4]
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Zebrafish (Danio rerio) TR beta- and TTR-based electrochemical biosensors: Construction and application for the evaluation of thyroid-disrupting activity of bisphenols
期刊论文
OAI收割
ENVIRONMENTAL POLLUTION, 2023, 卷号: 330, 页码: 9
作者:
Li, Yuejiao
;
Zhang, Zhenzhong
;
Wang, Jun
;
Shan, Yeqi
;
Tian, Hua
  |  
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2023/12/07
Thyroid-disrupting chemicals
Thyroid hormone receptor beta
Transthyretin
In vitro screening Assay
Electrochemical biosensor
Discovery of Highly Potent and Selective Thyroid Hormone Receptor βAgonists for the Treatment of Nonalcoholic Steatohepatitis
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 66, 期号: 5, 页码: 3284-3300
作者:
Hu, Liuyu
;
Gu, Yipei
;
Liang, Ju
;
Ning, Mengmeng
;
Yang, Junli
  |  
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2024/03/27
Hepatic thyroid hormone signalling modulates glucose homeostasis through the regulation of GLP-1 production via bile acid-mediated FXR antagonism
期刊论文
OAI收割
NATURE COMMUNICATIONS, 2022, 卷号: 13, 期号: 1, 页码: 16
作者:
Yan, Ying
;
Niu, Zhoumin
;
Sun, Chao
;
Li, Peng
;
Shen, Siyi
  |  
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2022/12/13
Nongenomic effects and mechanistic study of butyl benzyl phthalate-induced thyroid disruption: Based on integrated in vitro, in silico assays and proteome analysis
期刊论文
OAI收割
SCIENCE OF THE TOTAL ENVIRONMENT, 2022, 卷号: 836, 期号: 0, 页码: 155715
作者:
Li, Jian
;
Xu, Ying
;
Jiang, Yuhao
;
Li, Na
;
Li, Zhanjie
  |  
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2022/11/09
HORMONE
CELLS
RECEPTOR
ALPHA(V)BETA(3)
PROLIFERATION
ACTIVATION
TOXICITY
EXPOSURE
GROWTH
ESTERS
Thyroid Hormone Disruption by Organophosphate Esters Is Mediated by Nuclear/Membrane Thyroid Hormone Receptors: In Vitro, In Vivo, and In Silico Studies
期刊论文
OAI收割
ENVIRONMENTAL SCIENCE & TECHNOLOGY, 2022, 卷号: 56, 期号: 7, 页码: 4241-4250
作者:
Li, Jian
;
Xu, Ying
;
Li, Na
;
Zuo, Rui
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2022/11/09
FLAME RETARDANTS
INTEGRIN ALPHA(V)BETA(3)
TRIPHENYL PHOSPHATE
EXPOSURE
ALPHA-V-BETA-3
EMBRYOS/LARVAE
ACTIVATION
TOXICITY
ANIMALS
TDCPP
Multiple bioanalytical methods reveal a thyroid-disrupting mechanism related to the membrane receptor integrin alpha(v)beta(3)
期刊论文
OAI收割
ENVIRONMENTAL POLLUTION, 2021, 卷号: 279, 页码: -
作者:
Kong, Dongdong
;
Li, Jian
;
Li, Na
;
Zhang, Shurong
;
Xu, Ying
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2021/12/23
DEHP
Thyroid-disrupting effect
Toxic mechanism
Integrin alpha(v)beta(3)
ERK1/2
Integration of Computational Toxicology, Toxicogenomics Data Mining, and Omics Techniques to Unveil Toxicity Pathways
期刊论文
OAI收割
ACS SUSTAINABLE CHEMISTRY & ENGINEERING, 2021, 卷号: 9, 期号: 11, 页码: 4130-4138
作者:
Wang, Xiaoqing
;
Li, Fei
;
Chen, Jingwen
;
Ji, Chenglong
;
Wu, Huifeng
  |  
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2021/05/22
Adverse outcome pathway (AOP)
Comparative toxicogenomics database (CTD)
Triphenyl phosphate (TPP)
Molecular dynamics (MD)
Transcriptome analyses
Interaction of BDE-47 with nuclear receptors (NRs) based on the cytotoxicity: In vitro investigation and molecular interaction
期刊论文
OAI收割
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY, 2021, 卷号: 208, 页码: -
作者:
Song, Jiayi
;
Li, Yunxiu
;
Zhao, Chunyan
;
Zhou, Qunfang
;
Zhang, Jianqing
  |  
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2021/12/22
BDE-47
Nuclear receptors
Molecular simulation
RXR alpha
Cytotoxicity
TDCPP mimics thyroid hormones associated with the activation of integrin alpha(v)beta(3) and ERK1/2
期刊论文
OAI收割
CHEMOSPHERE, 2020, 卷号: 256, 页码: 1-9
作者:
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2021/09/15
TDCPP
BDCPP
Thyroid disruption
Integrin alpha(v)beta(3)
ERK1/2
德克隆类化合物对甲状腺系统的干扰效应及其分子机制
学位论文
OAI收割
北京: 中国科学院生态环境研究中心, 2020
作者:
朱剑桥
  |  
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2021/07/07
德克隆类化合物、甲状腺激素受体、竞争结合、t-screen、报告基因
Dechloranes, Thyroid Hormone Receptor, Ligand Binding Assay, T-screen Assay, Reporter Gene Assay