机构

• 上海药物研究所 [30]
• 化学研究所 [2]
• 合肥物质科学研究院 [2]
• 近代物理研究所 [2]
• 上海神经科学研究所 [1]
• 大连化学物理研究所 [1]
• 更多

采集方式

• OAI收割 [41]

内容类型

• 期刊论文 [39]
• 学位论文 [2]

发表日期

• 2023 [2]
• 2022 [2]
• 2021 [7]
• 2020 [3]
• 2019 [4]
• 2018 [4]
• 更多

学科主题

• Biochemist... [2]

筛选

浏览/检索结果: 共41条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择提交时间升序提交时间降序发表日期升序发表日期降序题名升序题名降序作者升序作者降序 Physiological and Pathological Functions of TRPM7 Channel and Its Small-molecule Modulators 期刊论文  OAI收割 PROGRESS IN BIOCHEMISTRY AND BIOPHYSICS, 2023, 卷号: 50, 期号: 12, 页码: 2856-2868 作者:  Wang, Yun-Qi;  Guan, Zi-Yue;  Gao, Zhao-Bing;  Zheng, Yue-Ming   |  收藏  |  浏览/下载：11/0  |  提交时间：2024/04/09 TRPM7  ion channel  physiological function  disease  small molecule modulators   Design, Synthesis, and Bioevaluation of Pyrido[2,3-d]pyrimidin-7-ones as Potent SOS1 Inhibitors 期刊论文  OAI收割 ACS MEDICINAL CHEMISTRY LETTERS, 2023, 页码: 183-190 作者:  Liu, Meiying;  Zhou, Guizhen;  Su, Wenhong;  Gu, Yuejiao;  Gao, Mingshan   |  收藏  |  浏览/下载：7/0  |  提交时间：2024/03/27 KRAS mutation  SOS1-KRAS interaction  SOS1 inhibitor  combination therapy   Key Considerations in Targeted Protein Degradation Drug Discovery and Development 期刊论文  OAI收割 FRONTIERS IN CHEMISTRY, 2022, 卷号: 10 作者:  Qin, Liena;  Dai, Han;  Wang, Junfeng   |  收藏  |  浏览/下载：28/0  |  提交时间：2022/12/23 targeted protein degradation  PROTAC  molecular glue  chemically induced proximity  drug discovery and development   CDK9 inhibitors in cancer research 期刊论文  OAI收割 RSC MEDICINAL CHEMISTRY, 2022 作者:  Huang, Zhi;  Wang, Tianqi;  Wang, Cheng;  Fan, Yan   |  收藏  |  浏览/下载：10/0  |  提交时间：2022/12/23 Allosteric Modulators Enhancing GLP-1 Binding to GLP-1R via a Transmembrane Site 期刊论文  OAI收割 ACS CHEMICAL BIOLOGY, 2021, 卷号: 16, 期号: 11, 页码: 2444-2452 作者:  Wang, Jiang;  Yang, Dehua;  Cheng, Xi;  Yang, Linlin;  Wang, Zhaohui   |  收藏  |  浏览/下载：39/0  |  提交时间：2022/01/04 Recent Progress and Clinical Development of Inhibitors that Block MDM4/p53 Protein-Protein Interactions 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 15, 页码: 10621-10640 作者:  Zhang, Shiyan;  Lou, Jianfeng;  Li, Yafang;  Zhou, Feilong;  Yan, Ziqin   |  收藏  |  浏览/下载：25/0  |  提交时间：2021/11/04 Discovery of potential small molecular SARS-CoV-2 entry blockers targeting the spike protein 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2021, 页码: 9 作者:  Wang, Lin;  Wu, Yan;  Yao, Sheng;  Ge, Huan;  Zhu, Ya   |  收藏  |  浏览/下载：94/0  |  提交时间：2021/11/04 SARS-CoV-2  natural products  virtual screening  spike protein  protein-protein interaction modulators   Identification of novel anti-inflammatory Nur77 modulators by virtual screening 期刊论文  OAI收割 BIOORGANIC CHEMISTRY, 2021, 卷号: 112, 页码: 7 作者:  Ding, Xiaoyu;  Zhao, Zijie;  Wu, Yue;  Zhang, Hao;  Chen, Kaixian   |  收藏  |  浏览/下载：23/0  |  提交时间：2021/08/17 Nur77  Binding site evaluation  Virtual Screening  Inflammation   Molecular insights into ago-allosteric modulation of the human glucagon-like peptide-1 receptor 期刊论文  OAI收割 NATURE COMMUNICATIONS, 2021, 卷号: 12, 期号: 1, 页码: 11 作者:  Cong, Zhaotong;  Chen, Li-Nan;  Ma, Honglei;  Zhou, Qingtong;  Zou, Xinyu   |  收藏  |  浏览/下载：61/0  |  提交时间：2021/08/17 Aberrant Bcl-x splicing in cancer: from molecular mechanism to therapeutic modulation 期刊论文  OAI收割 Journal of Experimental & Clinical Cancer Research, 2021, 卷号: 40, 期号: 1 作者:  Dou,Zhihui;  Zhao,Dapeng;  Chen,Xiaohua;  Xu,Caipeng;  Jin,Xiaodong   |  收藏  |  浏览/下载：23/0  |  提交时间：2021/12/09 Bcl-x  Alternative splicing  Cell apoptosis  Splicing correction  Splice-switching oligonucleotides  Small molecular modulators