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• 上海药物研究所 [13]
• 水生生物研究所 [3]
• 海洋研究所 [3]
• 上海生物化学与细胞生... [3]
• 成都生物研究所 [2]
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• OAI收割 [30]

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• 期刊论文 [29]
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• 2024 [1]
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• 2021 [3]
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浏览/检索结果: 共30条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择提交时间升序提交时间降序发表日期升序发表日期降序题名升序题名降序作者升序作者降序 Novel imidazo[1,2,4] triazole derivatives: Synthesis, fluorescence, bioactivity for SHP1 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 265, 页码: 15 作者:  Yan, Xue;  Zhang, Chun;  Gao, Li-Xin;  Liu, Min -Min;  Yang, Yu-Ting   |  收藏  |  浏览/下载：8/0  |  提交时间：2024/02/27 Imidazo[124] triazole derivatives  Fluorescence property  SHP1  Bioactivity  Cellular imaging   Novel thieno[2,3-b]quinoline-procaine hybrid molecules: A new class of allosteric SHP-1 activators evolved from PTP1B inhibitors 期刊论文  OAI收割 CHINESE CHEMICAL LETTERS, 2023, 卷号: 34, 期号: 8, 页码: 6 作者:  Xu, Lei;  Xuyan, Xuyang;  Minmi, Minmin;  Wang, Zhiji;  Shee, Chao   |  收藏  |  浏览/下载：27/0  |  提交时间：2023/10/17 Activator  PTPs  Inhibitor  Thieno[2  b ]quinoline derivatives  Diffuse large B-cell lymphoma   Theoretical study and application of 2-phenyl-1,3,4-thiadiazole derivatives with optical and inhibitory activity against SHP1 期刊论文  OAI收割 PHYSICAL CHEMISTRY CHEMICAL PHYSICS, 2021, 页码: 14 作者:  Zhang, Chun;  Sun, Yi-Tao;  Gao, Li-Xin;  Feng, Bo;  Yan, Xue   |  收藏  |  浏览/下载：47/0  |  提交时间：2022/01/18 Synthesis and biological evaluation of 2,5-diaryl-1,3,4-oxadiazole derivatives as novel Src homology 2 domain-containing protein tyrosine phosphatase 2 (SHP2) inhibitors 期刊论文  OAI收割 BIOORGANIC CHEMISTRY, 2021, 卷号: 116, 页码: 13 作者:  Meng, Xiang-Dong;  Gao, Li-Xin;  Wang, Zhi-Jia;  Feng, Bo;  Zhang, Chun   |  收藏  |  浏览/下载：61/0  |  提交时间：2021/12/01 2,5-diphenyl-1,3,4-oxadiazole derivatives  SHP2  Inhibitors  Structure-activity relationships (SAR)   Synthesis of 5-Phenyl-1,3,4-thiadiazole Derivatives and Their Biochemical Evaluation against Src Homology 2 Domain-Containing Protein Tyrosine Phosphatase 1 (SHP1) 期刊论文  OAI收割 CHINESE JOURNAL OF ORGANIC CHEMISTRY, 2021, 卷号: 41, 期号: 8, 页码: 3097-3105 作者:  Yu Lijie;  Feng Bo;  Wang Zhijia;  Gao Lixin;  Zhang Chun   |  收藏  |  浏览/下载：94/0  |  提交时间：2021/11/04 5-phenyl-1,3,4-thiadiazole derivatives  Src homology 2 domain-containing protein tyrosine phosphatase 1 (SHP1)  inhibitors  structure-activity relationships   Transcriptomic analysis of glioblastoma multiforme providing new insights into GPR17 signaling communication 期刊论文  OAI收割 JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS, 2020, 页码: 14 作者:  Mutharasu, Gnanavel;  Murugesan, Akshaya;  Konda Mani, Saravanan;  Yli-Harja, Olli;  Kandhavelu, Meenakshisundaram   |  收藏  |  浏览/下载：32/0  |  提交时间：2020/12/10 GPR17  signaling networks  glioblastoma multiforme  RNA-Seq  protein–  protein interface  kinases   Disrupting phosphatase SHP2 in macrophages protects mice from high-fat diet-induced hepatic steatosis and insulin resistance by elevating IL-18 levels 期刊论文  OAI收割 JOURNAL OF BIOLOGICAL CHEMISTRY, 2020, 卷号: 295, 期号: 31, 页码: 10842-10856 作者:  Liu, Wen;  Yin, Ye;  Wang, Meijing;  Fan, Ting;  Zhu, Yuyu   |  收藏  |  浏览/下载：86/0  |  提交时间：2020/12/24 Src homology 2 domain containing tyrosine phosphatase-2 (SHP2)  hepatic steatosis  insulin resistance  caspase-1  interleukin 18 (IL-18)  fatty liver  metabolic disorder  inflammation  cytokine signaling  caspase 1 (CASP1)  tyrosine-protein phosphatase (tyrosine phosphatase)  macrophage   Phytochemical and biological studies on rare and endangered plants endemic to China. Part XIV. Structurally diverse terpenoids from the twigs and needles of the endangered plant Picea brachytyla 期刊论文  OAI收割 PHYTOCHEMISTRY, 2020, 卷号: 169, 页码: 11 作者:  Jiang, Wei;  Xiong, Juan;  Zang, Yi;  Li, Junmin;  Osman, Ezzat E. A.   |  收藏  |  浏览/下载：28/0  |  提交时间：2020/07/01 Picea brachytyla (Franch.) E.Pritz.  Pinaceae  Endangered plant  Terpenoids  Brachytylins  ATP citrate lyase (ACL)  SHP2 tyrosine phosphatase   Alternatively spliced down syndrome cell adhesion molecule (Dscam) controls innate immunity in crab 期刊论文  OAI收割 JOURNAL OF BIOLOGICAL CHEMISTRY, 2019, 卷号: 294, 期号: 44, 页码: 16440-16450 作者:  Li, Dan;  Wan, Zhicheng;  Li, Xuejie;  Duan, Ming;  Yang, Lei   |  收藏  |  浏览/下载：46/0  |  提交时间：2020/04/07 invertebrate  bacteria  gene transcription  toll receptor  antimicrobial peptide (AMP)  Dock  Dscam  ERK  protein?protein interaction   Solution NMR structure and ligand identification of human Gas7 SH3 domain reveal a typical SH3 fold but a non-canonical ligand-binding mode 期刊论文  OAI收割 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2019, 卷号: 516, 期号: 4, 页码: 1190-1195 作者:  Nie, Yao;  Zhu, Jiang;  Ramelot, Theresa A.;  Kennedy, Michael A.;  Liu, Maili   |  收藏  |  浏览/下载：79/0  |  提交时间：2019/10/14 Growth arrest specific 7  Src homology 3  NMR structure  Praline-rich  Phage display