机构

• 上海药物研究所 [137]
• 上海生物化学与细胞... [41]
• 大连化学物理研究所 [21]
• 中国科学院大学 [16]
• 合肥物质科学研究院 [14]
• 海洋研究所 [13]
• 更多

采集方式

• OAI收割 [308]
• iSwitch采集 [23]

内容类型

• 期刊论文 [321]
• 学位论文 [6]
• 会议论文 [4]

发表日期

• 2022 [8]
• 2021 [8]
• 2020 [5]
• 2019 [22]
• 2018 [18]
• 2017 [31]
• 更多

学科主题

• Biochemis... [16]
• Cell Biol... [13]
• Oncology [8]
• Neuroscien... [7]
• Science & ... [6]
• Biochemist... [4]
• 更多

筛选

浏览/检索结果: 共331条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择提交时间升序提交时间降序发表日期升序发表日期降序题名升序题名降序作者升序作者降序 New chromone derivatives bearing thiazolidine-2,4-dione moiety as potent PTP1B inhibitors: Synthesis and biological activity evaluation 期刊论文  OAI收割 BIOORGANIC CHEMISTRY, 2024, 卷号: 143, 页码: 9 作者:  Zheng, Yingying;  Lu, Li;  Li, Mengyue;  Xu, Dehua;  Zhang, Laishun   |  收藏  |  浏览/下载：8/0  |  提交时间：2024/01/26 Chromone  Thiazolidine-2  4-dione  Protein tyrosine phosphatase 1B  Inhibitors   Structure-based drug discovery of novel fused- pyrazolone carboxamide derivatives as potent and selective AXL inhibitors 期刊论文  OAI收割 ACTA PHARMACEUTICA SINICA B, 2023, 卷号: 13, 期号: 12, 页码: 4918-4933 作者:  Fang, Feifei;  Dai, Yang;  Wang, Hao;  Ji, Yinchun;  Liang, Xuewu   |  收藏  |  浏览/下载：7/0  |  提交时间：2024/01/26 derivatives  Antitumor drug development  Potential AXL inhibitor  Antitumor activity  Structure-based drug design  Fused-pyrazolone carboxamide   Comparative proteomic and phosphoproteomic analysis reveals differential heat response mechanism in two congeneric oyster species 期刊论文  OAI收割 ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY, 2023, 卷号: 263, 页码: 19 作者:  Wang, Chaogang;  Du, Mingyang;  Jiang, Zhuxiang;  Cong, Rihao;  Wang, Wei   |  收藏  |  浏览/下载：6/0  |  提交时间：2023/12/13 Heat stress  Oysters  Crassostrea angulata  Crassostrea gigas  Phosphorylation   ASK120067 potently suppresses B-cell or T-cell malignancies in vitro and in vivo by inhibiting BTK and ITK 期刊论文  OAI收割 FRONTIERS IN PHARMACOLOGY, 2022, 卷号: 13, 页码: 9 作者:  Song, Peiran;  Bai, Gang;  Chan, Shingpan;  Zhang, Tao;  Tong, Linjiang   |  收藏  |  浏览/下载：27/0  |  提交时间：2023/04/10 Bruton's tyrosine kinase  interleukin-2-inducible T cell kinase  ASK120067  B-cell lymphoma  T-cell leukemia   Discovery of Pyrrolo[2,3-d]pyrimidine derivatives as potent and selective colony stimulating factor 1 receptor kinase inhibitors 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 243 作者:  Liang, Xiaofei;  Wang, Chun;  Wang, Beilei;  Liu, Juan;  Qi, Shuang   |  收藏  |  浏览/下载：38/0  |  提交时间：2022/12/23 CSF1R inhibitor  Kinase inhibitor  Macrophage polarization   Matrix stiffness exacerbates the proinflammatory responses of vascular smooth muscle cell through the DDR1-DNMT1 mechanotransduction axis 期刊论文  OAI收割 BIOACTIVE MATERIALS, 2022, 卷号: 17, 页码: 406-424 作者:  Wang, Jin;  Xie, Si-an;  Li, Ning;  Zhang, Tao;  Yao, Weijuan   |  收藏  |  浏览/下载：36/0  |  提交时间：2022/06/10 Matrix stiffness  Inflammation  DDR1  DNMT1  Mechanotransduction   Coronarin A modulated hepatic glycogen synthesis and gluconeogenesis via inhibiting mTORC1/S6K1 signaling and ameliorated glucose homeostasis of diabetic mice 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2022, 页码: 14 作者:  Huang, Su-Ling;  Xie, Wei;  Ye, Yang-Liang;  Liu, Jia;  Qu, Hui   |  收藏  |  浏览/下载：35/0  |  提交时间：2022/11/11 type 2 diabetes mellitus  coronarin A  glycogen synthesis  gluconeogenesis  mTORC1  IRS1   Vav2 is a novel APP-interacting protein that regulates APP protein level 期刊论文  OAI收割 SCIENTIFIC REPORTS, 2022, 卷号: 12 作者:  Zhang, Youjia;  Yang, Xiaxin;  Liu, Yongrui;  Ge, Liang;  Wang, Jiarong   |  收藏  |  浏览/下载：24/0  |  提交时间：2022/12/23 原肌球蛋白受体激酶(TRK)抑制剂的研究进展 期刊论文  OAI收割 有机化学, 2022, 卷号: 42, 期号: 7, 页码: 2055-2069 作者:  杨竣喆;  许子超;  李淳朴;  程远征;  柳红   |  收藏  |  浏览/下载：10/0  |  提交时间：2024/03/21 tropomyosin receptor kinase  anticancer  inhibitor   Dual-responsive nanoparticles loading bevacizumab and gefitinib for molecular targeted therapy against non-small cell lung cancer 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2022, 页码: 11 作者:  Zhao, Zi-tong;  Wang, Jue;  Fang, Lei;  Qian, Xin-di;  Cai, Ying   |  收藏  |  浏览/下载：36/0  |  提交时间：2022/08/16 nanoparticles  molecular targeted therapy  non-small cell lung cancer  dual-responsive  controlled release