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Integrated chemoenzymatic synthesis of a comprehensive sulfated ganglioside glycan library to decipher functional sulfoglycomics and sialoglycomics
期刊论文
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NATURE CHEMISTRY, 2024, 页码: 16
Authors:
Xu, Zhuojia
;
Liu, Yating
;
Liu, Jialin
;
Ma, Wenjing
;
Zhang, Zhumin
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View/Download:6/0
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Submit date:2024/07/12
创伤后应激障碍遗传学研究数据整合与挖掘
学位论文
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中国科学院心理研究所: 中国科学院大学, 2024
Authors:
徐苓
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View/Download:24/0
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Submit date:2024/07/11
创伤后应激障碍
遗传学
元分析
数据挖掘
Flexible scaffold-based cheminformatics approach for polypharmacological drug design
期刊论文
OAI收割
CELL, 2024, 卷号: 187, 期号: 9, 页码: 38
Authors:
Chen, Zhangcheng
;
Yu, Jing
;
Wang, Huan
;
Xu, Peiyu
;
Fan, Luyu
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View/Download:8/0
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Submit date:2024/07/12
D3Rings: A Fast and Accurate Method for Ring System Identification and Deep Generation of Drug-Like Cyclic Compounds
期刊论文
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JOURNAL OF CHEMICAL INFORMATION AND MODELING, 2024, 卷号: 64, 期号: 3, 页码: 724-736
Authors:
Ma, Minfei
;
Zhang, Xinben
;
Zhou, Liping
;
Han, Zijian
;
Shi, Yulong
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View/Download:33/0
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Submit date:2024/03/13
Exploring the mechanism of the PTP1B inhibitors by molecular dynamics and experimental study
期刊论文
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JOURNAL OF MOLECULAR GRAPHICS & MODELLING, 2023, 卷号: 125, 页码: 12
Authors:
Zhao, Tian-Tian
;
Hu, Hao-Jie
;
Gao, Li-Xin
;
Zhou, Yu-Bo
;
Zhu, Yun-Long
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Submit date:2023/10/17
Protein tyrosine phosphatases inhibitors
PTP1B inhibitors
Mechanism study
Molecular dynamics
Molecular recognition of niacin and lipid-lowering drugs by the human hydroxycarboxylic acid receptor 2
期刊论文
OAI收割
CELL REPORTS, 2023, 卷号: 42, 期号: 11, 页码: 19
Authors:
Zhu, Shengnan
;
Yuan, Qingning
;
Li, Xinzhu
;
He, Xinheng
;
Shen, Shiyi
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View/Download:207/0
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Submit date:2024/01/16
different ligands
recognition
ligand selectivity
receptor
Origin and mineralization processes of REE during magmatic-hydrothermal evolution: Insights from in-situ geochemistry of calcite from the Weishan REE deposit, eastern North China Craton
期刊论文
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ORE GEOLOGY REVIEWS, 2023, 卷号: 162, 页码: 16
Authors:
Zhao, Lang-Ye
;
Lan, Ting-Guang
;
Fan, Hong-Rui
;
Lan, Jun
;
Wang, Hong
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View/Download:14/0
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Submit date:2024/01/02
LA-ICP-MS
Calcite
Magmatic-hydrothermal evolution
REE mineralization
Weishan REE deposit
Ultralow-background SERS substrates for reliable identification of organic pollutants and degradation intermediates
期刊论文
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JOURNAL OF HAZARDOUS MATERIALS, 2023, 卷号: 460, 页码: 9
Authors:
Zhang, Longfei
;
Zhao, Rongfang
;
Wu, Yanzhou
;
Zhang, Zhiyang
;
Chen, Yan
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View/Download:22/0
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Submit date:2023/11/15
Surface-enhanced Raman scattering
Surface plasmon resonance
Silver nanoparticles
Organic pollutants
Degradation intermediates
'Passive' nanoparticles for organ-selective systemic delivery: design, mechanism and perspective
期刊论文
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CHEMICAL SOCIETY REVIEWS, 2023
Authors:
Fu, Liyi
;
Zhang, Yang
;
Farokhzad, Ryan A.
;
Mendes, Barbara B.
;
Conde, Joao
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View/Download:13/0
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Submit date:2023/11/17
Structural insights into the interaction of three Y- shaped ligands with PI3Kα
期刊论文
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PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2023, 卷号: 120, 期号: 34, 页码: 9
Authors:
Zhou, Qingtong
;
Liu, Xiao
;
Neri, Dario
;
Li, Wenxin
;
Favalli, Nicholas
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View/Download:18/0
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Submit date:2023/12/08
phosphoinositide 3-kinase
drug target
ligand
binding pocket
chemical scaffold