中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
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上海药物研究所 [65]
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Opportunities and challenges of fucoidan for tumors therapy
期刊论文
OAI收割
CARBOHYDRATE POLYMERS, 2024, 卷号: 324, 页码: 13
作者:
Yu, Haoyu
;
Zhang, Quanbin
;
Farooqi, Ammad Ahmad
;
Wang, Jing
;
Yue, Yang
  |  
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2024/04/07
Brown algae
Fucoidan
Structure
Anti-tumor
Structure-based development of potent and selective type-II kinase inhibitors of RIPK1
期刊论文
OAI收割
ACTA PHARMACEUTICA SINICA B, 2024, 卷号: 14, 期号: 1, 页码: 319-334
作者:
Qin, Ying
;
Li, Dekang
;
Qi, Chunting
;
Xiang, Huaijiang
;
Meng, Huyan
  |  
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2024/03/06
RIPK1
Necroptosis
Type-II kinase inhibitors
Rational design
Lead optimization
Structure-activity relationship
Anti-inflammation
Preclinical drug discovery
From bench to bedside: current development and emerging trend of KRAS-targeted therapy
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2023, 页码: 18
作者:
Chen, Yi
;
Liu, Qiu-pei
;
Xie, Hua
;
Ding, Jian
  |  
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2024/01/16
KRAS mutation
KRAS(G12C) inhibitor
Pan-KRAS inhibitor
SHP2 allosteric inhibitor
SOS1 inhibitor
combination therapy
Preclinical and early clinical studies of a novel compound SYHA1813 that efficiently crosses the blood-brain barrier and exhibits potent activity against glioblastoma
期刊论文
OAI收割
ACTA PHARMACEUTICA SINICA B, 2023, 卷号: 13, 期号: 12, 页码: 4748-4764
作者:
Liu, Yingqiang
;
Zhan, Zhengsheng
;
Kang, Zhuang
;
Li, Mengyuan
;
Lv, Yongcong
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2024/01/26
Small molecule inhibitor
Tumor microenvironment
Immune-checkpoint
immune-deficient mouse models
including temozolomide (TMZ) insensitive tumors. Notably
NIR-II fluorescence-guided liver cancer surgery by a small molecular HDAC6 targeting probe
期刊论文
OAI收割
EBIOMEDICINE, 2023, 卷号: 98, 页码: 18
作者:
Wang, Bo
;
Tang, Chu
;
Lin, En
;
Jia, Xiaohua
;
Xie, Ganyuan
  |  
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2024/02/22
Hepatocellular carcinoma
Second near-infrared window
Molecular imaging
HDAC6
Fluorescence guided surgery
Indole-3-Propionic Acid, a Gut Microbiota Metabolite, Protects Against the Development of Postoperative Delirium
期刊论文
OAI收割
ANNALS OF SURGERY, 2023, 卷号: 278, 期号: 6, 页码: E1164-E1174
作者:
Zhou, Xue
;
Wu, Xinbo
;
Wu, Yan
;
Yang, Liuyue
;
Shi, Eleanor
  |  
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2024/04/09
gut microbiota
indole-3-propionic acid
anesthesia
surgery
postoperative delirium
TI17, a novel compound, exerts anti-MM activity by impairing Trip13 function of DSBs repair and enhancing DNA damage
期刊论文
OAI收割
CANCER MEDICINE, 2023, 页码: 14
作者:
  |  
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2023/12/11
DNA damage
DSBs repair
myeloma
TI17
Trip13
[
68
Ga]Ga-AUNP-12 PET imaging to assess the PD-L1 status in preclinical and first-in-human study
期刊论文
OAI收割
EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING, 2023, 页码: 11
作者:
Zhou, Ming
;
Xiang, Shijun
;
Zhao, Yajie
;
Tang, Yongxiang
;
Yang, Jinhui
  |  
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2023/11/16
PD-1/PD-L1
Immune checkpoints
PET/CT imaging
Immunotherapy
Combining gut microbiota modulation and chemotherapy by capecitabine-loaded prebiotic nanoparticle improves colorectal cancer therapy
期刊论文
OAI收割
NATURE COMMUNICATIONS, 2023, 卷号: 14, 期号: 1, 页码: 16
作者:
Lang, Tianqun
;
Zhu, Runqi
;
Zhu, Xiao
;
Yan, Wenlu
;
Li, Yu
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2023/10/17
Preclinical Evaluation of 9MW2821, a Site-Specific Monomethyl Auristatin E-based Antibody-Drug Conjugate for Treatment of Nectin-4-expressing Cancers
期刊论文
OAI收割
MOLECULAR CANCER THERAPEUTICS, 2023, 卷号: 22, 期号: 8, 页码: 913-925
作者:
Zhou, Wei
;
Fang, Peng
;
Yu, Dongan
;
Ren, Hongyuan
;
You, Meng
  |  
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2023/10/17