中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
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上海药物研究所 [55]
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Limosilactobacillus reuteri and caffeoylquinic acid synergistically promote adipose browning and ameliorate obesity-associated disorders
期刊论文
OAI收割
MICROBIOME, 2022, 卷号: 10, 期号: 1, 页码: 22
作者:
Liu, Yameng
;
Zhong, Xianchun
;
Lin, Suqin
;
Xu, Hualing
;
Liang, Xinyu
  |  
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2023/04/10
Obesity
Prebiotic
Probiotics
Short-chain fatty acids
Propionate
Thermogenesis
Browning
Changes in Disposition of Ezetimibe and Its Active Metabolites Induced by Impaired Hepatic Function: The Influence of Enzyme and Transporter Activities
期刊论文
OAI收割
PHARMACEUTICS, 2022, 卷号: 14, 期号: 12, 页码: 22
作者:
Xie, Ningjie
;
Wang, Hong
;
Qin, Hua
;
Guo, Zitao
;
Xue, Hao
  |  
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2023/04/10
hepatic impairment
ezetimibe
active metabolites
phase II enzymes
transporters
first-pass metabolism
inhibitory bile acids
Novel fluorescent GLUT1 inhibitor for precision detection and fluorescence image-guided surgery in oral squamous cell carcinoma
期刊论文
OAI收割
INTERNATIONAL JOURNAL OF CANCER, 2022, 卷号: 151, 期号: 3, 页码: 450-462
作者:
Tian, Yu
;
Tang, Chu
;
Shi, Guangyuan
;
Wang, Guorong
;
Du, Yang
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2022/07/25
fluorescence molecular imaging
glucose transporter type 1
image-guided surgery
mouth neoplasms
WZB117
Pharmacokinetics, Mass Balance, and Metabolism of the Novel Urate Transporter 1 Inhibitor [14C]HR011303 in Humans: Metabolism Is Mediated Predominantly by UDP-Glucuronosyltransferase
期刊论文
OAI收割
DRUG METABOLISM AND DISPOSITION, 2022, 卷号: 50, 期号: 6, 页码: 798-808
作者:
Zheng, Yuandong
;
Zhang, Hua
;
Liu, Mengling
;
Li, Guangze
;
Ma, Sheng
  |  
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2022/08/16
SLC1A1-mediated cellular and mitochondrial influx of R-2-hydroxyglutarate in vascular endothelial cells promotes tumor angiogenesis in IDH1-mutant solid tumors
期刊论文
OAI收割
CELL RESEARCH, 2022, 页码: 21
作者:
Wang, Xiaomin
;
Chen, Ziqi
;
Xu, Jun
;
Tang, Shuai
;
An, Nan
  |  
收藏
  |  
浏览/下载:39/0
  |  
提交时间:2022/06/15
Bile acid and receptors: biology and drug discovery for nonalcoholic fatty liver disease
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2022, 页码: 17
作者:
Jiao, Ting-ying
;
Ma, Yuan-di
;
Guo, Xiao-zhen
;
Ye, Yun-fei
;
Xie, Cen
  |  
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2022/06/15
bile acids
nonalcoholic fatty liver disease
nonalcoholic steatohepatitis
drug target
Farnesoid X receptor
G protein-coupled bile acid receptor
The novel therapeutic strategy of vilazodone-donepezil chimeras as potent triple-target ligands for the potential treatment of Alzheimer's disease with comorbid depression
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 229, 页码: 22
作者:
Li, Xiaokang
;
Li, Jinwen
;
Huang, Yunyuan
;
Gong, Qi
;
Fu, Yan
  |  
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2022/06/15
Alzheimer's disease
Depression
Comorbidity
Multi-target-directed ligands
The unconventional prefoldin RPB5 interactor mediates the gravitropic response by modulating cytoskeleton organization and auxin transport in Arabidopsis
期刊论文
OAI收割
JOURNAL OF INTEGRATIVE PLANT BIOLOGY, 2022, 卷号: 64, 期号: 10, 页码: 1916-1934
作者:
Yang, Yi
;
Liu, Fang
;
Liu, Le
;
Zhu, Mingyue
;
Yuan, Jinfeng
  |  
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2024/03/07
Arabidopsis
auxin
cytoskeleton
PIN2
prefoldin (PFD)
unconventional prefoldin RPB5 interactor (URI)
Amygdalar k-opioid receptor-dependent upregulating glutamate transporter 1 mediates depressive-like behaviors of opioid abstinence
期刊论文
OAI收割
CELL REPORTS, 2021, 卷号: 37, 期号: 5, 页码: 21
作者:
Zan, Gui-Ying
;
Wang, Yu-Jun
;
Li, Xue-Ping
;
Fang, Jun-Fan
;
Yao, Song-Yu
  |  
收藏
  |  
浏览/下载:56/0
  |  
提交时间:2021/12/16
Effects of Food on the Pharmacokinetic Properties and Mass Balance of Henagliflozin in Healthy Male Volunteers
期刊论文
OAI收割
CLINICAL THERAPEUTICS, 2021, 卷号: 43, 期号: 9, 页码: E264-E273
作者:
Chen, Zhen-dong
;
Chen, Qian
;
Zhu, Yun-ting
;
Zhang, Yi-fan
;
Zhan, Yan
  |  
收藏
  |  
浏览/下载:46/0
  |  
提交时间:2022/01/04
henagliflozin
food effects
mass balance
pharmacokinetics
SGLT-2 inhibitor