中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [7]
采集方式
OAI收割 [7]
内容类型
期刊论文 [7]
发表日期
2023 [1]
2022 [1]
2021 [1]
2020 [1]
2019 [1]
2018 [2]
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专题:上海药物研究所
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AXL antibody and AXL-ADC mediate antitumor efficacy via targeting AXL in tumor-intrinsic epithelial-mesenchymal transition and tumor-associated M2-like macrophage
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2023, 页码: 14
作者:
Pei, Jin-peng
;
Wang, Yue
;
Ma, Lan-ping
;
Wang, Xin
;
Liu, Liang
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2023/04/10
AXL
NSCLC
TNBC
M2-macrophage
antibody-drug conjugate
Interfering with alternatively activated macrophages by CSF-1R inhibition exerts therapeutic capacity on allergic airway inflammation
期刊论文
OAI收割
BIOCHEMICAL PHARMACOLOGY, 2022, 卷号: 198, 页码: 14
作者:
Xiang, Caigui
;
Fan, Chen
;
Lu, Qiukai
;
Liu, Moting
;
Lu, Huimin
  |  
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2022/06/15
Asthma
Macrophages
CSF-1R
Allergy
Inflammation
A novel silicone derivative of natural osalmid (DCZ0858) exerts anti-multiple myeloma activity by promoting cell apoptosis and inhibiting cell cycle and mTOR signaling
期刊论文
OAI收割
AMERICAN JOURNAL OF TRANSLATIONAL RESEARCH, 2021, 卷号: 13, 期号: 10, 页码: 11439-11449
作者:
Bu, Wenxuan
;
Li, Bo
;
Feng, Lijin
;
Feng, Qilin
;
Hu, Ke
  |  
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2021/12/16
Multiple myeloma
DCZ0858
mTOR
bone marrow microenvironment
cell proliferation
cell apoptosis
A novel phosphoramide compound, DCZ0847, displays in vitro and in vivo anti-myeloma activity, alone or in combination with bortezomib
期刊论文
OAI收割
CANCER LETTERS, 2020, 卷号: 478, 页码: 45-55
作者:
Chen, Gege
;
Hu, Ke
;
Sun, Haiguo
;
Zhou, Jinfeng
;
Song, Dongliang
  |  
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2020/07/01
Multiple myeloma
Bone marrow microenvironment
DNA damage
JAK2/STAT3 pathway
DCZ0814 induces apoptosis and G0/G1 phase cell cycle arrest in myeloma by dual inhibition of mTORC1/2
期刊论文
OAI收割
CANCER MANAGEMENT AND RESEARCH, 2019, 卷号: 11, 页码: 4797-4808
作者:
Kong, Yuanyuan
;
Li, Bo
;
Chang, Shuaikang
;
Gao, Lu
;
Xu, Zhijian
  |  
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2020/07/01
DCZ0814
multiple myeloma
mTOR
bone marrow microenvironment
apoptosis
Rafoxanide, an organohalogen drug, triggers apoptosis and cell cycle arrest in multiple myeloma by enhancing DNA damage responses and suppressing the p38 MAPK pathway
期刊论文
OAI收割
Cancer letters, 2018, 卷号: 444, 页码: 45-59
作者:
Xiao, Wenqin
;
Xu, Zhijian
;
Chang, Shuaikang
;
Li, Bo
;
Yu, Dandan
  |  
收藏
  |  
浏览/下载:98/0
  |  
提交时间:2019/01/08
Dual inhibition of mTORC1/2 by DCZ0358 induces cytotoxicity in multiple myeloma and overcomes the protective effect of the bone marrow microenvironment
期刊论文
OAI收割
CANCER LETTERS, 2018, 卷号: 421, 页码: 135-144
作者:
Gao, Lu
;
Li, Bo
;
Yang, Guang
;
Liu, Peng
;
Lan, Xiucai
  |  
收藏
  |  
浏览/下载:37/0
  |  
提交时间:2019/01/08
mTOR
Multiple myeloma
Bone marrow microenvironment
Apoptosis