中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [296]
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OAI收割 [296]
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期刊论文 [294]
会议论文 [2]
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2024 [5]
2023 [30]
2022 [26]
2021 [34]
2020 [16]
2019 [19]
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共296条,第1-10条
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专题:上海药物研究所
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Development of Potent MALT1 Inhibitors Featuring a Novel "2-Thioxo-2,3-dihydrothiazolo[4,5-
d
]pyrimidin-7(6
H
)-one" Scaffold for the Treatment of B Cell Lymphoma
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 4, 页码: 2884-2906
作者:
Liang, Xuewu
;
Yu, Haolan
;
Liang, Renwen
;
Feng, Zhuanghui
;
Saidahmatov, Abdusaid
  |  
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2024/04/09
Nanobodies as negative allosteric modulators for human calcium sensing receptor
期刊论文
OAI收割
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2024, 卷号: 695, 页码: 9
作者:
Cui, Qianqian
;
Wang, Lu
;
Wang, Haonan
;
Chen, Xiaochen
;
Han, Li
  |  
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2024/04/09
G-protein-coupled receptor
Extracellular calcium sensing receptor
Nanobody
Cryo-electron microscope
Systemic Ca 2+homoeostasis
Discovery of a potent and selective covalent threonine tyrosine kinase (TTK) inhibitor
期刊论文
OAI收割
BIOORGANIC CHEMISTRY, 2024, 卷号: 143, 页码: 16
作者:
Sun, Yaoliang
;
Chen, Zhiwen
;
Liu, Guobin
;
Chen, Xiaoai
;
Shi, Zihan
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2024/03/25
Inhibitor
Cancer
Threonine tyrosine kinase (TTK)
Covalent
SIBP-03, a novel anti-HER3 antibody, exerts antitumor effects and synergizes with EGFR- and HER2-targeted drugs
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2024, 页码: 10
作者:
Li, Wen-jing
;
Xie, Cheng-ying
;
Zhu, Xi
;
Tang, Jiao
;
Wang, Lei
  |  
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2024/02/19
SIBP-03
HER3
HER3-targeted therapy
neuregulin 1
EGFR
HER2
Proteogenomic characterization of small cell lung cancer identifies biological insights and subtype-specific therapeutic strategies
期刊论文
OAI收割
CELL, 2024, 卷号: 187, 期号: 1, 页码: 49
作者:
Liu, Qian
;
Zhang, Jing
;
Guo, Chenchen
;
Wang, Mengcheng
;
Wang, Chenfei
  |  
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2024/02/27
Single-cell RNA sequencing reveals a hierarchical transcriptional regulatory network of terpenoid biosynthesis in cotton secretory glandular cells
期刊论文
OAI收割
MOLECULAR PLANT, 2023, 卷号: 16, 期号: 12, 页码: 1990-2003
作者:
Lin, Jia-Ling
;
Chen, Longxian
;
Wu, Wen-Kai
;
Guo, Xiao-Xiang
;
Yu, Cheng-Hui
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2024/01/26
From bench to bedside: current development and emerging trend of KRAS-targeted therapy
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2023, 页码: 18
作者:
Chen, Yi
;
Liu, Qiu-pei
;
Xie, Hua
;
Ding, Jian
  |  
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2024/01/16
KRAS mutation
KRAS(G12C) inhibitor
Pan-KRAS inhibitor
SHP2 allosteric inhibitor
SOS1 inhibitor
combination therapy
Synthesis, evaluation and molecular dynamics study of human toll-like receptor 2/6 specific monoacyl lipopeptides as candidate immunostimulants
期刊论文
OAI收割
BIOORGANIC CHEMISTRY, 2023, 卷号: 141, 页码: 17
作者:
Zhu, Yueyue
;
Liu, Bo
;
Chen, Zonglong
;
Wang, Xianyang
;
Wang, Yujie
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2023/12/08
Toll -like receptor 2/6 agonists
PamCS
Structure-activity relationship
Lipopeptide
Immunostimulants
The aminosteroid U73122 promotes oligodendrocytes generation and myelin formation
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2023, 页码: 12
作者:
Cui, Shi-hao
;
Suo, Na
;
Yang, Ying
;
Wu, Xuan
;
Guo, Shi-meng
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2023/12/11
oligodendrocyte
oligodendrocyte progenitor cell
differentiation
remyelination
U73122
Loops Mediate Agonist-Induced Activation of the Stimulator of Interferon Genes Protein
期刊论文
OAI收割
JOURNAL OF CHEMICAL INFORMATION AND MODELING, 2023, 页码: 9
作者:
Li, Rui
;
Chen, Lin
;
He, Xinheng
;
Cao, Duanhua
;
Zhang, Zehong
  |  
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2023/12/11