机构

• 上海药物研究所 [45]

采集方式

• OAI收割 [45]

内容类型

• 期刊论文 [44]
• 会议论文 [1]

发表日期

• 2024 [2]
• 2023 [4]
• 2022 [4]
• 2021 [1]
• 2020 [3]
• 2019 [4]
• 更多

学科主题

筛选

浏览/检索结果: 共45条，第1-10条 帮助 限定条件 专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择提交时间升序提交时间降序发表日期升序发表日期降序题名升序题名降序作者升序作者降序 Design, Synthesis, and Biological Evaluation of Potent and Selective PROTAC Degraders of Oncogenic KRASG12D 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 2, 页码: 1147-1167 作者:  Zhou, Chuan;  Fan, Zisheng;  Gu, Yuejiao;  Ge, Zhiming;  Tao, Zhaofan   |  收藏  |  浏览/下载：10/0  |  提交时间：2024/02/27 Role of F-box proteins in human upper gastrointestinal tumors 期刊论文  OAI收割 BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER, 2024, 卷号: 1879, 期号: 1, 页码: 16 作者:  Zhang, Che;  Pan, Guangzhao;  Qin, Jiang-Jiang   |  收藏  |  浏览/下载：22/0  |  提交时间：2024/02/27 F-box protein  Upper gastrointestinal cancer  E3 ubiquitin ligase  Ubiquitin   Qing-Zhi-Tiao-Gan-Tang (QZTGT) prevents nonalcoholic steatohepatitis (NASH) by expression pattern correction 期刊论文  OAI收割 JOURNAL OF ETHNOPHARMACOLOGY, 2023, 卷号: 317, 页码: 14 作者:  Chu, Hang;  Zhang, Weitao;  Tan, Yan;  Diao, Zhipeng;  Li, Peng   |  收藏  |  浏览/下载：22/0  |  提交时间：2023/10/17 Fibrosis  Inflammation  Lipogenesis  NASH  QZTGT  TMNP   Macrophage autophagy deficiency-induced CEBPB accumulation alleviates atopic dermatitis via impairing M2 polarization 期刊论文  OAI收割 CELL REPORTS, 2023, 卷号: 42, 期号: 11, 页码: 24 作者:  Zhu, Yongcheng;  Liu, Yunyao;  Ma, Yuxiang;  Tan, Cheng;  He, Yuan   |  收藏  |  浏览/下载：25/0  |  提交时间：2024/01/16 The new direction of drug development: Degradation of undruggable targets through targeting chimera technology 期刊论文  OAI收割 MEDICINAL RESEARCH REVIEWS, 2023, 页码: 54 作者:  Liang, Xuewu;  Ren, Hairu;  Han, Fengyang;  Liang, Renwen;  Zhao, Jiayan   |  收藏  |  浏览/下载：20/0  |  提交时间：2024/01/16 chimeric design  degradation System  PROTAC  targeted degradation technology  undruggable targets   Xanthine dehydrogenase rewires metabolism and the survival of nutrient deprived lung adenocarcinoma cells by facilitating UPR and autophagic degradation 期刊论文  OAI收割 INTERNATIONAL JOURNAL OF BIOLOGICAL SCIENCES, 2023, 卷号: 19, 期号: 3, 页码: 772-788 作者:  Chen, Man-man;  Guo, Wei;  Chen, Si-meng;  Guo, Xiao-zhen;  Xu, Lan   |  收藏  |  浏览/下载：2/0  |  提交时间：2024/03/27 Xanthine dehydrogenase  nucleoside degradation  cell survival  UPR  autophagy  LUAD   Discovery of Highly Potent Nicotinamide Phosphoribosyltransferase Degraders for Efficient Treatment of Ovarian Cancer 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2022, 页码: 15 作者:  Bi, Kaijian;  Cheng, Junfei;  He, Shipeng;  Fang, Yuxin;  Huang, Min   |  收藏  |  浏览/下载：16/0  |  提交时间：2023/04/10 Structure-based rational design enables efficient discovery of a new selective and potent AKT PROTAC degrader 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 238, 页码: 15 作者:  Zhu, Cheng-Liang;  Luo, Xiaomin;  Tian, Tian;  Rao, Zijian;  Wang, Hanlin   |  收藏  |  浏览/下载：28/0  |  提交时间：2022/08/16 AKT  Protein kinase B  PROTAC  Chemical degrader  Rational design   Tumour-derived extracellular vesicle membrane hybrid lipid nanovesicles enhance siRNA delivery by tumour-homing and intracellular freeway transportation 期刊论文  OAI收割 JOURNAL OF EXTRACELLULAR VESICLES, 2022, 卷号: 11, 期号: 3, 页码: 16 作者:  Zhou, Xin;  Miao, Yunqiu;  Wang, Ying;  He, Shufang;  Guo, Linmiao   |  收藏  |  浏览/下载：36/0  |  提交时间：2022/06/15 tumour-derived extracellular vesicles  hybrid lipid nanovesicles  tumour homing  siRNA delivery  hepatocellular carcinoma   SH2 Domain-Containing Phosphatase 2 Inhibition Attenuates Osteoarthritis by Maintaining Homeostasis of Cartilage Metabolism via the Docking Protein 1/Uridine Phosphorylase 1/Uridine Cascade 期刊论文  OAI收割 ARTHRITIS & RHEUMATOLOGY, 2022, 页码: 12 作者:  Liu, Qianqian;  Zhai, Linhui;  Han, Mingrui;  Shi, Dongquan;  Sun, Ziying   |  收藏  |  浏览/下载：27/0  |  提交时间：2022/06/15