中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
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上海药物研究所 [27]
上海营养与健康研究... [16]
大连化学物理研究所 [8]
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期刊论文 [120]
发表日期
2019 [120]
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Biochemist... [7]
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Genetics &... [5]
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发表日期:2019
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Common activation mechanism of class A GPCRs
期刊论文
OAI收割
ELIFE, 2019, 卷号: 8, 页码: 31
作者:
Zhou, Qingtong
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收藏
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浏览/下载:76/0
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提交时间:2020/07/01
Design, synthesis, and biological evaluation of thieno[3,2-d]pyrimidine derivatives as potential simplified phosphatidylinositol 3-kinase alpha inhibitors
期刊论文
OAI收割
CHEMICAL BIOLOGY & DRUG DESIGN, 2019, 卷号: 94, 期号: 6, 页码: 2013-2022
作者:
Yang, Xiuyan
;
Deng, Meng
;
Zhang, Xi
;
Wang, Yi
;
Song, Kun
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收藏
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浏览/下载:31/0
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提交时间:2020/07/01
PI3K alpha inhibitors
proliferation inhibition
thieno[3
2-d]pyrimidine derivatives
AZD9291 inactivates the PRC2 complex to mediate tumor growth inhibition
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2019, 卷号: 40, 期号: 12, 页码: 1587-1595
作者:
Zhang, Kai-li
;
Shen, Qian-qian
;
Fang, Yan-fen
;
Sun, Yi-ming
;
Ding, Jian
  |  
收藏
  |  
浏览/下载:48/0
  |  
提交时间:2020/07/01
PRC2
EZH2-EED
AZD9291
miR-34a
non-canonical base pairing
Lysine acetylation contributes to development, aflatoxin biosynthesis and pathogenicity in Aspergillus flavus
期刊论文
OAI收割
ENVIRONMENTAL MICROBIOLOGY, 2019, 卷号: 21, 期号: 12, 页码: 4792-4807
作者:
Yang, Guang
;
Yue, Yuewei
;
Ren, Silin
;
Yang, Mingkun
;
Zhang, Yi
  |  
收藏
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浏览/下载:30/0
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提交时间:2020/05/08
Simultaneous determination of alflutinib and its active metabolite in human plasma using liquid chromatography-tandem mass spectrometry
期刊论文
OAI收割
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2019, 卷号: 176, 页码: 6
作者:
Liu, Xiaoyun
;
Li, Wei
;
Zhang, Yifan
;
Jian, Yong
;
Zhao, Qianyu
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收藏
  |  
浏览/下载:43/0
  |  
提交时间:2020/07/01
LC-MS/MS
Alflutinib
AST2818
Pharmacokinetics
Human plasma
Genome-Wide Comparisons of Mutations Induced by Carbon-Ion Beam and Gamma-Rays Irradiation in Rice via Resequencing Multiple Mutants
期刊论文
OAI收割
FRONTIERS IN PLANT SCIENCE, 2019, 卷号: 10, 页码: 13
作者:
Yang, Guili
;
Luo, Wenlong
;
Zhang, Jian
;
Yan, Xiancheng
;
Du, Yan
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收藏
  |  
浏览/下载:23/0
  |  
提交时间:2022/01/19
Oryza sativa L
carbon-ion beams (CIBs) irradiation
gamma rays (GRs)
resequencing
single base substitution (SBS)
InDels
multiple nucleotide variant (MNV)
structural variant (SV)
Genetic polymorphisms in mutagenesis progeny of Arabidopsis thaliana irradiated by carbon-ion beams and gamma-rays irradiations
期刊论文
OAI收割
INTERNATIONAL JOURNAL OF RADIATION BIOLOGY, 2019, 页码: 9
作者:
Chen, Xia
;
Feng, Hui
;
Du, Yan
;
Luo, Shanwei
;
Li, Wenjian
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收藏
  |  
浏览/下载:20/0
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提交时间:2022/01/19
Carbon-ion beams
gamma-rays
Arabidopsis thaliana
ISSR
RAPD
Comparison of colonial volvocine algae based on phylotranscriptomic analysis of gene family evolution and natural selection
期刊论文
OAI收割
EUROPEAN JOURNAL OF PHYCOLOGY, 2019, 期号: 1, 页码: 13
作者:
Hu, Yuxin
;
Xing, Weiyue
;
Song, Huiyin
;
Hu, Zhengyu
;
Liu, Guoxiang
  |  
收藏
  |  
浏览/下载:23/0
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提交时间:2020/05/08
Coalescent-based approach
colonial volvocine algae
gene family evolution
phylotranscriptomic
relaxed purifying selection
substitution rates
Design, synthesis, and biological evaluation of novel tetrahydroprotoberberine derivatives (THPBs) as proprotein convertase subtilisin/kexin type 9 (PCSK9) modulators for the treatment of hyperlipidemia
期刊论文
OAI收割
ACTA PHARMACEUTICA SINICA B, 2019, 卷号: 9, 期号: 6, 页码: 1216-1230
作者:
Wu, Chenglin
;
Xi, Cong
;
Tong, Junhua
;
Zhao, Jing
;
Jiang, Hualiang
  |  
收藏
  |  
浏览/下载:43/0
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提交时间:2020/07/01
PCSK9
Tetrahydroprotoberberine derivatives
Low-density lipoprotein cholesterol
Lipid-lowering
PCSK9 expression
Low-density lipoprotein receptor
Total cholesterol
Hyperlipidemia hamster
Liquid chromatography- mass spectrometry for analysis of DNA damages induced by environmental exposure
期刊论文
OAI收割
TRAC-TRENDS IN ANALYTICAL CHEMISTRY, 2019, 卷号: 120, 页码: -
作者:
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收藏
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浏览/下载:18/0
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提交时间:2020/09/10
DNA damage
DNA modification
Liquid chromatography-mass spectrometry
Environmental exposure
Environmental health