机构

• 上海药物研究所 [244]

采集方式

• OAI收割 [244]

内容类型

• 期刊论文 [239]
• 学位论文 [3]
• 会议论文 [2]

发表日期

• 2024 [3]
• 2023 [24]
• 2022 [22]
• 2021 [11]
• 2020 [14]
• 2019 [11]
• 更多

学科主题

• Chemistry [8]
• Biochemist... [5]
• Pharmacolo... [4]
• Biotechnol... [2]
• Virology [2]

筛选

浏览/检索结果: 共244条，第1-10条 帮助 限定条件 专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择提交时间升序提交时间降序发表日期升序发表日期降序题名升序题名降序作者升序作者降序 Development of Potent MALT1 Inhibitors Featuring a Novel "2-Thioxo-2,3-dihydrothiazolo[4,5-d]pyrimidin-7(6H)-one" Scaffold for the Treatment of B Cell Lymphoma 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 4, 页码: 2884-2906 作者:  Liang, Xuewu;  Yu, Haolan;  Liang, Renwen;  Feng, Zhuanghui;  Saidahmatov, Abdusaid   |  收藏  |  浏览/下载：15/0  |  提交时间：2024/04/09 Design, synthesis and biological evaluation of betulinic acid derivatives as potential inhibitors of 3CL-protease of SARS-CoV-2 期刊论文  OAI收割 STEROIDS, 2024, 卷号: 202, 页码: 8 作者:  Liu, Yaowen;  Nie, Tianqing;  Hou, Jinjun;  Long, Huali;  Zhang, Zijia   |  收藏  |  浏览/下载：14/0  |  提交时间：2024/03/13 3CLpro  SARS-CoV-2  Betulinic acid  Natural product  Inhibitory activity   Extracellular Matrix-Trapped Bioinspired Lipoprotein Prolongs Tumor Retention to Potentiate Antitumor Immunity 期刊论文  OAI收割 ADVANCED MATERIALS, 2024, 页码: 14 作者:  Wu, Yao;  Li, Yongping;  Hu, Zixin;  Li, Yuan;  Zhang, Shixuan   |  收藏  |  浏览/下载：19/0  |  提交时间：2024/02/27 antitumor responses  bioinspired lipoprotein  extracellular matrix  pomalidomide  tumor retention   A first-in-human phase 1 study of simnotrelvir, a 3CL-like protease inhibitor for treatment of COVID-19, in healthy adult subjects 期刊论文  OAI收割 EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2023, 卷号: 191, 页码: 9 作者:  Yang, Xin-Mei;  Yang, Yang;  Yao, Bu-Fan;  Ye, Pan-Pan;  Xu, Yan   |  收藏  |  浏览/下载：11/0  |  提交时间：2023/12/11 COVID-19  Simnotrelvir  Safety  Pharmacokinetics  Healthy subjects   C-terminal modification and functionalization of proteins via a self-cleavage tag triggered by a small molecule 期刊论文  OAI收割 NATURE COMMUNICATIONS, 2023, 卷号: 14, 期号: 1, 页码: 13 作者:  Zeng, Yue;  Shi, Wei;  Liu, Zhi;  Xu, Hao;  Liu, Liya   |  收藏  |  浏览/下载：6/0  |  提交时间：2024/02/19 Selective activator of human ClpP triggers cell cycle arrest to inhibit lung squamous cell carcinoma 期刊论文  OAI收割 NATURE COMMUNICATIONS, 2023, 卷号: 14, 期号: 1, 页码: 7069 作者:  Zhou, Lin-Lin;  Zhang, Tao;  Xue, Yun;  Yue, Chuan;  Pan, Yihui   |  收藏  |  浏览/下载：3/0  |  提交时间：2024/03/27 Deubiquitylating Enzymes in Cancer and Immunity 期刊论文  OAI收割 ADVANCED SCIENCE, 2023, 页码: 37 作者:  Ren, Jiang;  Yu, Peng;  Liu, Sijia;  Li, Ran;  Niu, Xin   |  收藏  |  浏览/下载：6/0  |  提交时间：2023/12/08 cancer  deubiquitylating enzymes (DUBs)  immunity  therapeutic approach   Structure-based development and preclinical evaluation of the SARS-CoV-2 3C-like protease inhibitor simnotrelvir 期刊论文  OAI收割 NATURE COMMUNICATIONS, 2023, 卷号: 14, 期号: 1, 页码: 15 作者:  Jiang, Xiangrui   |  收藏  |  浏览/下载：13/0  |  提交时间：2024/03/25 Assessment of the structure-activity relationship and antileukemic activity of diacylpyramide compounds as human ClpP agonists 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 258, 页码: 17 作者:  Zhang, Ranran;  Wang, Pengyu;  Wei, Bingyan;  Chen, Liang;  Song, Xiaomin   |  收藏  |  浏览/下载：20/0  |  提交时间：2023/10/17 ClpP agonists  Structure-activity relationship  Mitochondrial respiratory chain  Antileukemic therapy   Efficacy and safety of SIM0417 (SSD8432) plus ritonavir for COVID-19 treatment: a randomised, double-blind, placebo- controlled, phase 1b trial 期刊论文  OAI收割 LANCET REGIONAL HEALTH-WESTERN PACIFIC, 2023, 卷号: 38, 页码: 13 作者:  Wang, Fuxiang;  Xiao, Wen;  Tang, Yimin;  Cao, Mengli;  Shu, Dan   |  收藏  |  浏览/下载：12/0  |  提交时间：2023/10/17 Covid-19  3CL protease inhibitor  SARS-CoV-2 viral load  Alleviation of COVID-19 symptoms