中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
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上海药物研究所 [137]
合肥物质科学研究院 [41]
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OAI收割 [359]
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期刊论文 [354]
学位论文 [3]
会议论文 [2]
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2022 [359]
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Biochemist... [3]
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浏览/检索结果:
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Development of a novel PROTAC using the nucleic acid aptamer as a targeting ligand for tumor selective degradation of nucleolin
期刊论文
OAI收割
MOLECULAR THERAPY-NUCLEIC ACIDS, 2022, 卷号: 30
作者:
Zhang, Lin
;
Li, Ling
;
Wang, Xia
;
Liu, Huimin
;
Zhang, Yibin
  |  
收藏
  |  
浏览/下载:35/0
  |  
提交时间:2022/12/23
Hiding Payload Inside the IgG Fc Cavity Significantly Enhances the Therapeutic Index of Antibody-Drug Conjugates
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2022, 页码: 16
作者:
Shi, Wei
;
Zhang, Jianxin
;
Liu, Liya
;
Li, Wanzhen
;
Liu, Zhi
  |  
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2023/04/10
Chemotherapy-induced phlebitis via the GBP5/NLRP3 inflammasome axis and the therapeutic effect of aescin
期刊论文
OAI收割
BRITISH JOURNAL OF PHARMACOLOGY, 2022, 页码: 16
作者:
Liu, Peng
;
Ye, Lichun
;
Ren, Yongshen
;
Zhao, Guodun
;
Zhang, Yun
  |  
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2023/04/10
aescin
GBP5
NLRP3 inflammasome
phlebitis
vinorelbine
Dual inhibition of CHK1/FLT3 enhances cytotoxicity and overcomes adaptive and acquired resistance in FLT3-ITD acute myeloid leukemia
期刊论文
OAI收割
LEUKEMIA, 2022, 页码: 11
作者:
Jiang, Kailong
;
Li, Xuemei
;
Wang, Chang
;
Hu, Xiaobei
;
Wang, Peipei
  |  
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2023/04/10
Fused-ring alpha-pyrones from intramolecular C-H activation and their lipids-lowering activity associated with LXR-IDOL-LDLR axis regulation
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 244, 页码: 11
作者:
Mao, Yingle
;
Li, Jiaomeng
;
Tang, Chunping
;
Ma, Biao
;
Xu, Zhijian
  |  
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2023/04/10
C-H activation
One-pot intramolecular cyclization
?-Pyrone derivatives
LDL uptaking
LXR-IDOL-LDLR axis
In vivo lipids-lowering effect
ASK120067 potently suppresses B-cell or T-cell malignancies in vitro and in vivo by inhibiting BTK and ITK
期刊论文
OAI收割
FRONTIERS IN PHARMACOLOGY, 2022, 卷号: 13, 页码: 9
作者:
Song, Peiran
;
Bai, Gang
;
Chan, Shingpan
;
Zhang, Tao
;
Tong, Linjiang
  |  
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2023/04/10
Bruton's tyrosine kinase
interleukin-2-inducible T cell kinase
ASK120067
B-cell lymphoma
T-cell leukemia
DCZ19931, a novel multi-targeting kinase inhibitor, inhibits ocular neovascularization
期刊论文
OAI收割
SCIENTIFIC REPORTS, 2022, 卷号: 12, 期号: 1, 页码: 15
作者:
Zhang, Huiying
;
Li, Bo
;
Ding, Jingjuan
;
Ye, Rong
;
Xu, Zhijian
  |  
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2023/10/17
Disruption of C/EBP beta-Clec7a axis exacerbates neuroinflammatory injury via NLRP3 inflammasome-mediated pyroptosis in experimental neuropathic pain
期刊论文
OAI收割
JOURNAL OF TRANSLATIONAL MEDICINE, 2022, 卷号: 20, 期号: 1, 页码: 19
作者:
Wu, Dan
;
Zhang, Yanqiong
;
Zhao, Chunhui
;
Li, Qiuyue
;
Zhang, Junhong
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2023/04/10
C/EBP beta-Clec7a axis
Neuroinflammation
Neuropathic Pain
NLRP3 Inflammasome-mediated Pyroptosis
Curcumin nanoparticles combined with 3D printed bionic tumor models for breast cancer treatment
期刊论文
OAI收割
Biofabrication, 2022, 卷号: 15, 期号: 1
作者:
Su,Ya
;
Hu,Xueyan
;
Kang,Yue
  |  
收藏
  |  
浏览/下载:0/0
  |  
提交时间:2023/05/19
Chinese medicine nanoparticles
3D cell model
tumor treatment
drug screening
Discovery of Pyrrolo[2,3-d]pyrimidine derivatives as potent and selective colony stimulating factor 1 receptor kinase inhibitors
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 243
作者:
Liang, Xiaofei
;
Wang, Chun
;
Wang, Beilei
;
Liu, Juan
;
Qi, Shuang
  |  
收藏
  |  
浏览/下载:38/0
  |  
提交时间:2022/12/23
CSF1R inhibitor
Kinase inhibitor
Macrophage polarization