中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [811]
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OAI收割 [811]
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期刊论文 [783]
会议论文 [27]
项目 [1]
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2024 [8]
2023 [31]
2022 [40]
2021 [47]
2020 [44]
2019 [33]
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Chemistry [45]
Biochemis... [25]
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浏览/检索结果:
共811条,第1-10条
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专题:上海药物研究所
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A robust and validated LC-MS/MS method for the quantification of ramucirumab in rat and human serum using direct enzymatic digestion without immunoassay
期刊论文
OAI收割
JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 2024, 卷号: 1234, 页码: 11
作者:
Huang, Wen-si
;
Li, Wei-qiang
;
Yu, Xiong
;
Xue, Ming-zhen
;
Yuan, Ya-li
  |  
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2024/04/09
Anti -gastric cancer monoclonal antibody
Ramucirumab
LC -MS/MS
Method validation
Surrogate peptide
7-Dehydrocholesterol dictates ferroptosis sensitivity
期刊论文
OAI收割
NATURE, 2024, 卷号: 626, 期号: 7998, 页码: 29
作者:
Li, Yaxu
;
Ran, Qiao
;
Duan, Qiuhui
;
Jin, Jiali
;
Wang, Yanjin
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2024/04/09
Safety, pharmacokinetics, and food effect of sudapyridine (WX-081), a novel anti-tuberculosis candidate in healthy Chinese subjects
期刊论文
OAI收割
CTS-CLINICAL AND TRANSLATIONAL SCIENCE, 2024, 卷号: 17, 期号: 2, 页码: 10
作者:
Yu, Chengyin
;
Qian, Hongjie
;
Wu, Qingqing
;
Zou, Yang
;
Ding, Qicheng
  |  
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2024/03/06
Development and Validation of an ADA-Tolerant Assay for Quantification of an Exatecan-Based ADC in Monkey Plasma
期刊论文
OAI收割
MOLECULES, 2024, 卷号: 29, 期号: 3, 页码: 14
作者:
Tao, Yimin
;
Lu, Wei
;
Gao, Jinli
;
Yang, Shuangshuang
;
Ruan, Chaoyi
  |  
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2024/03/13
antibody-drug conjugate (ADC)
bioanalysis
anti-drug antibody (ADA)
ligand binding assay (LBA)
ADA-tolerant assay
A novel pterostilbene compound DCZ0825 induces macrophage M1 differentiation and Th1 polarization to exert anti-myeloma and immunomodulatory
期刊论文
OAI收割
INTERNATIONAL IMMUNOPHARMACOLOGY, 2024, 卷号: 127, 页码: 14
作者:
Zhang, Hui
;
Hu, Ke
;
Lu, Yumeng
;
Xu, Zhijian
;
Chen, Gege
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2024/03/25
Multiple myeloma
M1 macrophages
Th1 cells
Immunomodulatory
Metabolism investigation of the peptide-drug conjugate LN005 in rats using UHPLC-HRMS
期刊论文
OAI收割
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2024, 卷号: 238, 页码: 11
作者:
Wang, Weiqiang
;
Chen, Chong
;
Luo, Jing
;
Tang, Chongzhuang
;
Zheng, Yuandong
  |  
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2024/01/16
LN005
Metabolism
Peptide -drug conjugates
UHPLC-HRMS
Doxorubicin
Obesity induced disruption on diurnal rhythm of insulin sensitivity via gut microbiome-bile acid metabolism
期刊论文
OAI收割
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS, 2024, 卷号: 1869, 期号: 1, 页码: 13
作者:
Guo, Xiaozhen
;
Wang, Jiawen
;
Xu, Hualing
;
Wang, Yangyang
;
Cao, Yutang
  |  
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2024/01/16
Diurnal rhythm
Insulin sensitivity
Obesity
Gut microbiota
Ursodeoxycholic acid
Development and validation of a sensitive liquid chromatography-tandem mass spectrometry method for the assay of 12 substances in rat plasma and its application to rat pharmacokinetics of
Epimedium
and
Psoraleae Fructus
herb pair after oral administration
期刊论文
OAI收割
JOURNAL OF SEPARATION SCIENCE, 2024, 卷号: 47, 期号: 1, 页码: 17
作者:
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2024/02/27
compatibility behaviors
Epimedium
LC-MS/MS
pharmacokinetics
Psoraleae Fructus
Qing-Zhi-Tiao-Gan-Tang (QZTGT) prevents nonalcoholic steatohepatitis (NASH) by expression pattern correction
期刊论文
OAI收割
JOURNAL OF ETHNOPHARMACOLOGY, 2023, 卷号: 317, 页码: 14
作者:
Chu, Hang
;
Zhang, Weitao
;
Tan, Yan
;
Diao, Zhipeng
;
Li, Peng
  |  
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2023/10/17
Fibrosis
Inflammation
Lipogenesis
NASH
QZTGT
TMNP
Absorption, Distribution, Metabolism, and Excretion of [
14
C]BS1801, a Selenium-Containing Drug Candidate, in Rats
期刊论文
OAI收割
MOLECULES, 2023, 卷号: 28, 期号: 24, 页码: 16
作者:
Yang, Cheng
;
Xue, Mingzhen
;
He, Yifei
;
Yin, Hanwei
;
Yang, Chen
  |  
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2024/01/26
[C-14]BS1801
BS1801 (butaselen)
tissue distribution
metabolism
mass balance
selenium