中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [4]
上海有机化学研究所 [4]
大连化学物理研究所 [3]
水生生物研究所 [2]
西北高原生物研究所 [1]
昆明植物研究所 [1]
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OAI收割 [15]
内容类型
期刊论文 [15]
发表日期
2024 [2]
2022 [1]
2021 [1]
2018 [2]
2017 [2]
2015 [1]
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学科主题
天然产物有机化学 [4]
Multidisci... [1]
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Discovery of betulinic acid derivatives as gut-restricted TGR5 agonists: Balancing the potency and physicochemical properties
期刊论文
OAI收割
BIOORGANIC CHEMISTRY, 2024, 卷号: 144, 页码: 18
作者:
Zhuo, Ning
;
Yun, Ying
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2024/03/25
Type 2 Diabetes
TGR5 agonist
Betulinic acid
Gut-restricted
Gallbladder-filling effects
Kinetophores
Obesity induced disruption on diurnal rhythm of insulin sensitivity via gut microbiome-bile acid metabolism
期刊论文
OAI收割
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS, 2024, 卷号: 1869, 期号: 1, 页码: 13
作者:
Guo, Xiaozhen
;
Wang, Jiawen
;
Xu, Hualing
;
Wang, Yangyang
;
Cao, Yutang
  |  
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2024/01/16
Diurnal rhythm
Insulin sensitivity
Obesity
Gut microbiota
Ursodeoxycholic acid
Bile acid and receptors: biology and drug discovery for nonalcoholic fatty liver disease
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2022, 页码: 17
作者:
Jiao, Ting-ying
  |  
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2022/06/15
bile acids
nonalcoholic fatty liver disease
nonalcoholic steatohepatitis
drug target
Farnesoid X receptor
G protein-coupled bile acid receptor
Hepatocyte ATF3 protects against atherosclerosis by regulating HDL and bile acid metabolism
期刊论文
OAI收割
NATURE METABOLISM, 2021, 页码: 31
作者:
Xu, Yanyong
;
Li, Yuanyuan
;
Jadhav, Kavita
;
Pan, Xiaoli
;
Zhu, Yingdong
  |  
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2021/05/24
Plasma bile acid changes in type 2 diabetes correlated with insulin secretion in two-step hyperglycemic clamp
期刊论文
OAI收割
JOURNAL OF DIABETES, 2018, 卷号: 10, 期号: 11, 页码: 874-885
作者:
Xie, Xiaoyan
;
Ma, Jing
;
Xu, Min
;
Zhao, Xinjie
;
Gu, Weiqiong
  |  
收藏
  |  
浏览/下载:63/0
  |  
提交时间:2019/06/20
bile acid
hyperglycemic clamp
insulin secretion
type 2 diabetes mellitus
Dietary Bile Salt Types Influence the Composition of Biliary Bile Acids and Gut Microbiota in Grass Carp
期刊论文
OAI收割
FRONTIERS IN MICROBIOLOGY, 2018, 卷号: 9, 期号: 1, 页码: 13
作者:
Xiong, Fan
;
Wu, Shan-Gong
;
Zhang, Jing
;
Jakovlic, Ivan
;
Li, Wen-Xiang
  |  
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2019/07/02
bile acid
gut microbiota
lipid metabolism
freshwater fish
in vivo
The influence of diet on the grass carp intestinal microbiota and bile acids
期刊论文
OAI收割
AQUACULTURE RESEARCH, 2017, 卷号: 48, 期号: 9, 页码: 4934-4944
作者:
Zhang, Jing
;
Xiong, Fan
;
Wang, Gui-Tang
;
Li, Wen-Xiang
;
Li, Ming
  |  
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2019/08/01
grass carp
gut microbe
bile acids
diet
PPAR alpha activation protects against cholestatic liver injury
期刊论文
OAI收割
SCIENTIFIC REPORTS, 2017, 卷号: 7, 页码: 9967
作者:
Zhao, Qi
;
Yang, Rui
;
Wang, Jing
;
Hu, Dan-Dan
;
Li, Fei
  |  
收藏
  |  
浏览/下载:34/0
  |  
提交时间:2017/10/23
Primary Biliary-cirrhosis
Bile-acid Homeostasis
Receptor-alpha
Ursodeoxycholic Acid
Cholesterol 7-alpha-hydroxylase
Beta-oxidation
Fenofibrate
Therapy
Mice
Hepatotoxicity
A weighted relative difference accumulation algorithm for dynamic metabolomics data: long-term elevated bile acids are risk factors for hepatocellular carcinoma
期刊论文
OAI收割
scientific reports, 2015, 卷号: 5
作者:
Zhang, Weijian
;
Zhou, Lina
;
Yin, Peiyuan
;
Wang, Jinbing
;
Lu, Xin
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2015/11/17
A sensitive and selective HPLC-FLD method with fluorescent labeling for simultaneous detection of bile acid and free fatty acid in human serum
期刊论文
OAI收割
journal of chromatography b-analytical technologies in the biomedical and life sciences, 2012, 卷号: 895, 页码: 191-195
作者:
Li, Guo-Liang
;
Chen, Guang
;
Liu, Yue-Qiu
;
Jing, Nian-Hua
;
You, Jin-Mao
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2013/03/15
Bile acids
Free fatty acids
Human serum
Fluorescent labeling
HPLC-FLD