中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [43]
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OAI收割 [43]
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期刊论文 [43]
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2021 [1]
2020 [1]
2017 [1]
2016 [1]
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2013 [2]
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Oncology [2]
Pharmacolo... [2]
Cell Biolo... [1]
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专题:上海药物研究所
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Combined treatment with FABP4 inhibitor ameliorates rosiglitazone-induced liver steatosis in obese diabetic db/db mice
期刊论文
OAI收割
BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY, 2021, 页码: 10
作者:
Chen, Meng-Ting
;
Huang, Jun-Shang
;
Gao, Ding-Ding
;
Li, Ying-Xia
;
Wang, He-Yao
  |  
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2021/08/17
combined treatment
FABP4 inhibitor
liver steatosis
obese type 2 diabetes
rosiglitazone
Identification and structural insight of an effective PPAR gamma modulator with improved therapeutic index for anti-diabetic drug discovery
期刊论文
OAI收割
CHEMICAL SCIENCE, 2020, 卷号: 11, 期号: 8, 页码: 2260-2268
作者:
Jiang, Haowen
;
Zhou, X. Edward
;
Shi, Jingjing
;
Zhou, Zhi
;
Zhao, Guanguan
  |  
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2020/07/01
Identification of a novel selective PPAR gamma ligand with a unique binding mode and improved therapeutic profile in vitro
期刊论文
OAI收割
Scientific Reports, 2017, 卷号: 7
作者:
Yi, Wei
;
Shi, Jingjing
;
Zhao, Guanguan
;
Zhou, X. Edward
;
Suino-Powell, Kelly
  |  
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2019/01/08
Bavachinin, as a novel natural pan-PPAR agonist, exhibits unique synergistic effects with synthetic PPAR-gamma and PPAR-alpha agonists on carbohydrate and lipid metabolism in db/db and diet-induced obese mice
期刊论文
OAI收割
DIABETOLOGIA, 2016, 卷号: 59, 期号: 6, 页码: 1276-1286
作者:
Feng, Li
;
Luo, Huan
;
Xu, Zhijian
;
Yang, Zhuo
;
Du, Guoxin
  |  
收藏
  |  
浏览/下载:47/0
  |  
提交时间:2019/01/08
Alternative binding site
Bavachinin
Canonical ligand-binding pocket
Carbohydrate metabolism
Lipid metabolism
Pan-PPAR agonist
Synergistic effects
Rhodium(III)-catalyzed regioselective C2-amidation of indoles with N-(2,4,6-trichlorobenzoyloxy)amides and its synthetic application to the development of a novel potential PPAR gamma modulator
期刊论文
OAI收割
ORGANIC & BIOMOLECULAR CHEMISTRY, 2014, 卷号: 12, 期号: 35, 页码: 6831-6836
作者:
Shi, Jingjing
;
Zhao, Guanguan
;
Wang, Xiaowei
;
Xu, H. Eric
;
Yi, Wei
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2019/01/08
Latanoprost effectively ameliorates glucose and lipid disorders in db/db and ob/ob mice
期刊论文
OAI收割
DIABETOLOGIA, 2013, 卷号: 56, 期号: 12, 页码: 2702-2712
作者:
Wang, Gaihong
;
Xu, Xing
;
Yao, Xingang
;
Zhu, Zhiyuan
;
Yu, Liang
  |  
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2019/01/08
AMPK
Glucose and lipid metabolism
Latanoprost
RXR alpha/PPAR gamma heterodimer
Type 2 diabetes
HPN, a Synthetic Analogue of Bromophenol from Red Alga Rhodomela confervoides: Synthesis and Anti-Diabetic Effects in C57BL/KsJ-db/db Mice
期刊论文
OAI收割
MARINE DRUGS, 2013, 卷号: 11, 期号: 2, 页码: 350-362
作者:
Shi, Dayong
;
Guo, Shuju
;
Jiang, Bo
;
Guo, Chao
;
Wang, Tao
  |  
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2019/01/08
bromophenol
protein tyrosine phosphatase 1B inhibitor
db/db mouse model
anti-diabetes properties
Anti-Diabetic Effects of TongGuanWan, a Chinese Traditional Herbal Formula, in C57BL/KsJ-db/db Mice
期刊论文
OAI收割
PLANTA MEDICA, 2012, 卷号: 78, 期号: 1, 页码: 18-23
作者:
Tang, Yi Hong
;
Sun, Zhao Lin
;
Fan, Ming Song
;
Li, Zhi Xiong
;
Huang, Cheng Gang
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2019/01/08
TongGuanWan
herbal formula
type 2 diabetes
anti-diabetic effect
Reduction of Lipid Accumulation in HepG2 Cells by Luteolin is associated with Activation of AMPK and Mitigation of Oxidative Stress
期刊论文
OAI收割
PHYTOTHERAPY RESEARCH, 2011, 卷号: 25, 期号: 4, 页码: 588-596
作者:
Liu, Jin-Feng
;
Ma, Ying
;
Wang, Ying
;
Du, Zhi-Yan
;
Shen, Jing-Kang
  |  
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2019/01/08
luteolin
AMPK
SREBP-1c
FAS
CPT-1
reactive oxygen species
HL005-A new selective PPAR gamma antagonist specifically inhibits the proliferation of MCF-7
期刊论文
OAI收割
JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY, 2011, 卷号: 124, 期号: 3-5, 页码: 112-120
作者:
Lu, Weiqiang
;
Che, Peng
;
Zhang, Yanyan
;
Li, Honglin
;
Zou, Shien
  |  
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2019/01/08
Peroxisome proliferator-activated receptor-gamma
Selective antagonist
Anticancer
Apoptosis