中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [21]
采集方式
OAI收割 [21]
内容类型
期刊论文 [20]
会议论文 [1]
发表日期
2017 [21]
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发表日期:2017
专题:上海药物研究所
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Design, synthesis and biological evaluation of novel alpha-hederagenin derivatives with anticancer activity
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 141, 页码: 427-439
作者:
Liu, Xian-xuan
;
Yang, Yan-ting
;
Wang, Xiao
;
Wang, Kai-yi
;
Liu, Jia-qi
  |  
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2019/01/08
alpha-Hederagenin derivatives
Synthesis
Apoptosis
Cancer
Calcium Promotes Human Gastric Cancer via a Novel Coupling of Calcium-Sensing Receptor and TRPV4 Channel
期刊论文
OAI收割
CANCER RESEARCH, 2017, 卷号: 77, 期号: 23, 页码: 6499-6512
作者:
Xie, Rui
;
Xu, Jingyu
;
Xiao, Yufeng
;
Wu, Jilin
;
Wan, Hanxing
  |  
收藏
  |  
浏览/下载:80/0
  |  
提交时间:2019/01/08
Tying up tranylcypromine: Novel selective histone lysine specific demethylase 1 (LSD1) inhibitors
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 141, 页码: 101-112
作者:
Ji, Yue-Yang
;
Lin, Sen-Dong
;
Wang, Yu-Jie
;
Su, Ming-Bo
;
Zhang, Wei
  |  
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2019/01/08
Tranylcypromine
LSD1
Stereoselective cyclopropanation
Chiral synthesis
MAO-A
MAO-B
Application of Monodisperse PEGs in Pharmaceutics: Monodisperse Polidocanols
期刊论文
OAI收割
MOLECULAR PHARMACEUTICS, 2017, 卷号: 14, 期号: 10, 页码: 3473-3479
作者:
Yu, Zeqiong
;
Bo, Shaowei
;
Wang, Huiyuan
;
Li, Yu
;
Yang, Zhigang
  |  
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2019/01/08
monodisperse
polydisperse
polyethylene glycols (PEGs)
polidocanol
PEGylated drugs
A novel glucagon-like peptide-1/glucagon receptor dual agonist exhibits weight-lowering and diabetes-protective effects
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 138, 页码: 1158-1169
作者:
Zhou, Jie
;
Cai, Xingguang
;
Huang, Xun
;
Dai, Yuxuan
;
Sun, Lidan
  |  
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2019/01/08
Glucagon
GLP-1/GCGR agonist
Weight-lowering
Diabetes-protective
Docking-based structural splicing and reassembly strategy to develop novel deazapurine derivatives as potent B-Raf(V600E) inhibitors
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2017, 卷号: 38, 期号: 7, 页码: 1059-1068
作者:
Wang, Gui-min
;
Wang, Xiang
;
Zhu, Jian-ming
;
Guo, Bin-bin
;
Yang, Zhuo
  |  
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2019/01/08
B-Raf(V600E) inhibitor
anticancer
vemurafenib
deazapurine
fragment reassembly
molecular docking
structure-activity relationship
Polymeric Immunoglobulin Receptor Promotes Tumor Growth in Hepatocellular Carcinoma
期刊论文
OAI收割
HEPATOLOGY, 2017, 卷号: 65, 期号: 6, 页码: 1948-1962
作者:
Yue, Xihua
;
Ai, Jing
;
Xu, Yang
;
Chen, Yi
;
Huang, Min
  |  
收藏
  |  
浏览/下载:34/0
  |  
提交时间:2019/01/08
Structure-Based Discovery of 4-(6-Methoxy-2-methyl-4-(quinolin-4-yl)-9H-pyrimido[4,5-b]indol-7-yl)-3,5-dimethylisoxazole (CD161) as a Potent and Orally Bioavailable BET Bromodomain Inhibitor
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 60, 期号: 9, 页码: 3887-3901
作者:
Zhao, Yujun
;
Bai, Longchuan
;
Liu, Liu
;
McEachern, Donna
;
Stuckey, Jeanne A.
  |  
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2019/01/08
Cucurbitane Glucosides from the Crude Extract of Siraitia grosvenorii with Moderate Effects on PGC-1 alpha Promoter Activity
期刊论文
OAI收割
JOURNAL OF NATURAL PRODUCTS, 2017, 卷号: 80, 期号: 5, 页码: 1428-1435
作者:
Niu, Biao
;
Ke, Chang-Qiang
;
Li, Bo-Han
;
Li, Yuanyuan
;
Yi, Yongji
  |  
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2019/01/08
Dihydrocelastrol inhibits multiple myeloma cell proliferation and promotes apoptosis through ERK1/2 and IL-6/STAT3 pathways in vitro and in vivo
期刊论文
OAI收割
ACTA BIOCHIMICA ET BIOPHYSICA SINICA, 2017, 卷号: 49, 期号: 5, 页码: 420-427
作者:
Hu, Liangning
;
Wu, Huiqun
;
Li, Bo
;
Song, Dongliang
;
Yang, Guang
  |  
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2019/01/08
dihydrocelastrol
multiple myeloma
apoptosis