中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [64]
采集方式
OAI收割 [64]
内容类型
期刊论文 [64]
发表日期
2020 [64]
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发表日期:2020
专题:上海药物研究所
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Gigantol ameliorates CCl4-induced liver injury via preventing activation of JNK/cPLA2/12-LOX inflammatory pathway
期刊论文
OAI收割
SCIENTIFIC REPORTS, 2020, 卷号: 10, 期号: 1, 页码: 13
作者:
Xue, Yaru
;
Deng, Qiangqiang
;
Zhang, Qingli
;
Ma, Zhenghua
;
Chen, Binfan
  |  
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2021/05/24
Determination of the antidiabetic chemical basis of Phellodendri Chinensis Cortex by integrating hepatic disposition in vivo and hepatic gluconeogenese inhibition in vitro
期刊论文
OAI收割
JOURNAL OF ETHNOPHARMACOLOGY, 2020, 卷号: 263, 页码: 10
作者:
Tian, Xiaoting
;
Xu, Zhou
;
Hu, Pei
;
Yu, Yanyan
;
Li, Zhixiong
  |  
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2020/12/21
Phellodendri Chinensis cortex
Hepatic disposition
Pharmacokinetics
Berberine
Metabolites
Hepatic gluconeogenesis
Liquid chromatography-tandem mass spectrometric assay for TPN171 in human plasma
期刊论文
OAI收割
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2020, 卷号: 191, 页码: 8
作者:
Zhang, Mengqi
;
Liu, Haiming
;
He, Jiajin
;
Gui, Yuzhou
;
Qian, Hongjie
  |  
收藏
  |  
浏览/下载:37/0
  |  
提交时间:2020/12/24
TPN171
LC-MS/MS
Human plasma
Protein precipitation
Discovery and Optimization of Non-bile Acid FXR Agonists as Preclinical Candidates for the Treatment of Nonalcoholic Steatohepatitis
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 63, 期号: 21, 页码: 12748-12772
作者:
Li, Junyou
;
Liu, Mengqi
;
Li, Yazhou
;
Sun, Dan-dan
;
Shu, Zhihao
  |  
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2021/05/24
Therapy for Apnoea of Prematurity: A Retrospective Study on Effects of Standard Dose and Genetic Variability on Clinical Response to Caffeine Citrate in Chinese Preterm Infants
期刊论文
OAI收割
ADVANCES IN THERAPY, 2020, 页码: 20
作者:
He, Xin
;
Qiu, Jin-Chun
;
Lu, Ke-Yu
;
Guo, Hong-Li
;
Li, Ling
  |  
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2020/12/24
Adenosine receptors
AHR
AOP
Caffeine
Phosphodiesterase
Polymorphism
Therapeutic drug monitoring
Identify potent SARS-CoV-2 main protease inhibitors via accelerated free energy perturbation-based virtual screening of existing drugs
期刊论文
OAI收割
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2020, 卷号: 117, 期号: 44, 页码: 27381-27387
作者:
Li, Zhe
;
Li, Xin
;
Huang, Yi-You
;
Wu, Yaoxing
;
Liu, Runduo
  |  
收藏
  |  
浏览/下载:82/0
  |  
提交时间:2020/12/24
virtual screening
SARS-CoV-2
drug repurposing
free energy perturbation
main protease
Ruthenium-Catalyzed C-H Activations for the Synthesis of Indole Derivatives
期刊论文
OAI收割
CATALYSTS, 2020, 卷号: 10, 期号: 11, 页码: 27
作者:
Zhu, Haoran
;
Zhao, Sen
;
Zhou, Yu
;
Li, Chunpu
;
Liu, Hong
  |  
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2021/05/24
ruthenium
C-H activation
indole
Activation of SIK1 by phanginin A inhibits hepatic gluconeogenesis by increasing PDE4 activity and suppressing the cAMP signaling pathway
期刊论文
OAI收割
MOLECULAR METABOLISM, 2020, 卷号: 41, 页码: 15
作者:
Liu, Siwen
;
Huang, Suling
;
Wu, Xingde
;
Feng, Ying
;
Shen, Yu
  |  
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2020/12/24
Salt-inducible kinase 1
Phanginin A
Phosphodiesterase 4
Gluconeogenesis
cAMP
Dual Mechanisms of Novel CD73-Targeted Antibody and Antibody-Drug Conjugate in Inhibiting Lung Tumor Growth and Promoting Antitumor Immune-Effector Function
期刊论文
OAI收割
MOLECULAR CANCER THERAPEUTICS, 2020, 卷号: 19, 期号: 11, 页码: 2340-2352
作者:
Jin, Rui
;
Liu, Liang
;
Xing, Yun
;
Meng, Tao
;
Ma, Lanping
  |  
收藏
  |  
浏览/下载:61/0
  |  
提交时间:2020/12/24
A removable directing group-assisted Rh(iii)-catalyzed direct C-H bond activation/annulation cascade to synthesize highly fused isoquinolines
期刊论文
OAI收割
ORGANIC CHEMISTRY FRONTIERS, 2020, 卷号: 7, 期号: 20, 页码: 3186-3192
作者:
Cheng, Yilang
;
Han, Xu
;
Li, Junyou
;
Zhou, Yu
;
Liu, Hong
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2020/12/24