中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [21]
采集方式
OAI收割 [21]
内容类型
期刊论文 [21]
发表日期
2020 [21]
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专题:上海药物研究所
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发表日期:2020
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Anti-PD-L1 mediating tumor-targeted codelivery of liposomal irinotecan/JQ1 for chemo-immunotherapy
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 8
作者:
He, Zhi-di
;
Zhang, Meng
;
Wang, Yong-hui
;
He, Yang
;
Wang, Hai-rui
  |  
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2021/05/24
tumor-targeted delivery
immunogenic cell death
PD-1
PD-L1 blockade
tumor immune microenvironment
irinotecan
JQ1
immune checkpoint
DW14383 is an irreversible pan-FGFR inhibitor that suppresses FGFR-dependent tumor growth in vitro and in vivo
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 9
作者:
Dai, Meng-di
;
Wang, Yue-liang
;
Fan, Jun
;
Dai, Yang
;
Ji, Yin-chun
  |  
收藏
  |  
浏览/下载:66/0
  |  
提交时间:2021/05/24
receptor tyrosine kinase
FGFR inhibitor
DW14383
antitumor activity
Transcriptional and proteomic insights into the host response in fatal COVID-19 cases
期刊论文
OAI收割
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2020, 卷号: 117, 期号: 45, 页码: 28336-28343
作者:
Wu, Meng
;
Chen, Yaobing
;
Xia, Han
;
Wang, Changli
;
Tan, Chin Yee
  |  
收藏
  |  
浏览/下载:54/0
  |  
提交时间:2020/12/24
COVID-19
SARS-CoV-2
neutrophil
fibrosis
NETosis
New cembrane-type diterpenoids from the South China Sea soft coral Sinularia crassa and their alpha-glucosidase inhibitory activity
期刊论文
OAI收割
BIOORGANIC CHEMISTRY, 2020, 卷号: 104, 页码: 6
作者:
Wu, Meng-Jun
;
Wang, Hong
;
Jiang, Cheng-Shi
;
Guo, Yue-Wei
  |  
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2021/05/24
Sinularia crassa
Cembranoid
Modified Mosher's method
ECD calculation
alpha-Glucosidase inhibitor
Dual Mechanisms of Novel CD73-Targeted Antibody and Antibody-Drug Conjugate in Inhibiting Lung Tumor Growth and Promoting Antitumor Immune-Effector Function
期刊论文
OAI收割
MOLECULAR CANCER THERAPEUTICS, 2020, 卷号: 19, 期号: 11, 页码: 2340-2352
作者:
Jin, Rui
;
Liu, Liang
;
Xing, Yun
;
Meng, Tao
;
Ma, Lanping
  |  
收藏
  |  
浏览/下载:61/0
  |  
提交时间:2020/12/24
Systematic comparison of metabolic differences of Uncaria rhynchophylla in rat, mouse, dog, pig, monkey and human liver microsomes
期刊论文
OAI收割
ANALYTICAL AND BIOANALYTICAL CHEMISTRY, 2020, 页码: 7
作者:
Li, Hao-Jv
;
Wei, Wen-Long
;
Li, Zhen-Wei
;
Yao, Chang-Liang
;
Wang, Meng-Yuan
  |  
收藏
  |  
浏览/下载:39/0
  |  
提交时间:2020/12/24
Uncaria rhynchophylla
Indole alkaloids
Mass defect filter
Time-staggered targeted ion lists
Metabolite identification
Liver microsomes
Disrupting phosphatase SHP2 in macrophages protects mice from high-fat diet-induced hepatic steatosis and insulin resistance by elevating IL-18 levels
期刊论文
OAI收割
JOURNAL OF BIOLOGICAL CHEMISTRY, 2020, 卷号: 295, 期号: 31, 页码: 10842-10856
作者:
Liu, Wen
;
Yin, Ye
;
Wang, Meijing
;
Fan, Ting
;
Zhu, Yuyu
  |  
收藏
  |  
浏览/下载:86/0
  |  
提交时间:2020/12/24
Src homology 2 domain containing tyrosine phosphatase-2 (SHP2)
hepatic steatosis
insulin resistance
caspase-1
interleukin 18 (IL-18)
fatty liver
metabolic disorder
inflammation
cytokine signaling
caspase 1 (CASP1)
tyrosine-protein phosphatase (tyrosine phosphatase)
macrophage
USP28 and USP25 are downregulated by Vismodegib in vitro and in colorectal cancer cell lines
期刊论文
OAI收割
FEBS JOURNAL, 2020, 页码: 18
作者:
Wang, Hui
;
Meng, Qian
;
Ding, Yiluan
;
Xiong, Muya
;
Zhu, Mengying
  |  
收藏
  |  
浏览/下载:41/0
  |  
提交时间:2020/12/24
colorectal cancer
HDX-MS
inhibitor
USP25
USP28
Vismodegib
Hepatoprotective effects of total phenylethanoid glycosides from Acanthus ilicifolius L. against carbon tetrachloride-induced hepatotoxicity
期刊论文
OAI收割
JOURNAL OF ETHNOPHARMACOLOGY, 2020, 卷号: 256, 页码: 8
作者:
Zhang, Meng-Qi
;
Ren, Xia
;
Zhao, Qing
;
Yue, Shi-Jun
;
Fu, Xiu-Mei
  |  
收藏
  |  
浏览/下载:44/0
  |  
提交时间:2020/07/01
Acanthus ilicifolius L.
Total phenylethanoid glycosides
Hepatoprotective
Antioxidant
Design, synthesis and antiproliferative activity evaluation of a series of pyrrolo [2,1-f] [1,2,4] triazine derivatives
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2020, 卷号: 30, 期号: 12, 页码: 4
作者:
Xiang, Hao-Yue
;
Chen, Yan-Hong
;
Wang, Yi
;
Zhang, Xi
;
Ding, Jian
  |  
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2020/07/01
Antiproliferative
Cancer
Therapy
PI3K inhibitors
Pyrrolo [2,1-f][1,2,4] triazine
Kinase