机构

• 上海药物研究所 [27]

采集方式

• OAI收割 [27]

内容类型

• 期刊论文 [27]

发表日期

• 2021 [27]

学科主题

筛选

浏览/检索结果: 共27条，第1-10条 帮助 限定条件 专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位    发表日期：2021     条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择题名升序题名降序提交时间升序提交时间降序作者升序作者降序发表日期升序发表日期降序 GLP-1 mimetics as a potential therapy for nonalcoholic steatohepatitis 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2021, 页码: 11 作者:  Chen, Yan;  Xu, Ying-na;  Ye, Chen-yu;  Feng, Wen-bo;  Zhou, Qing-tong   |  收藏  |  浏览/下载：17/0  |  提交时间：2022/06/15 NAFLD  NASH  GLP-1R  GLP-1 mimetics  dual agonists  triple agonists  GPCR   Distal mutation V486M disrupts the catalytic activity of DPP4 by affecting the flap of the propeller domain 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2021, 页码: 9 作者:  Li, Teng-teng;  Peng, Cheng;  Wang, Ji-qiu;  Xu, Zhi-jian;  Su, Ming-bo   |  收藏  |  浏览/下载：65/0  |  提交时间：2022/01/18 DPP4  distal mutation  enzymatic activity  molecular dynamics simulation  structure-function mechanism   Advancing COVID-19 diagnosis with privacy-preserving collaboration in artificial intelligence 期刊论文  OAI收割 NATURE MACHINE INTELLIGENCE, 2021, 卷号: 3, 期号: 12, 页码: 1081-1089 作者:  Bai, Xiangd;  Wang, Hanchen;  Ma, Liya;  Xu, Yongchao;  Gan, Jiefeng   |  收藏  |  浏览/下载：63/0  |  提交时间：2022/01/18 Structures of the human cholecystokinin receptors bound to agonists and antagonists 期刊论文  OAI收割 NATURE CHEMICAL BIOLOGY, 2021, 卷号: 17, 期号: 12, 页码: 1230-1237 作者:  Zhang, Xuefeng;  He, Chenglin;  Wang, Mu;  Zhou, Qingtong;  Yang, Dehua   |  收藏  |  浏览/下载：12/0  |  提交时间：2024/03/21 Applications of Asymmetric Petasis Reaction in the Synthesis of Chiral Amines 期刊论文  OAI收割 ACTA CHIMICA SINICA, 2021, 卷号: 79, 期号: 11, 页码: 1345-1359 作者:  Li, Yi   |  收藏  |  浏览/下载：30/0  |  提交时间：2022/01/04 Petasis reaction  chiral amine  boronic acid  asymmetric synthesis  asymmetric catalysis   Cryo-EM structures of PI3K alpha reveal conformational changes during inhibition and activation 期刊论文  OAI收割 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2021, 卷号: 118, 期号: 45, 页码: 9 作者:  Liu, Xiao;  Yang, Su;  Hart, Jonathan R.;  Xu, Yingna;  Zou, Xinyu   |  收藏  |  浏览/下载：51/0  |  提交时间：2022/01/04 phosphoinositide 3-kinase (PI3K)  activation  inhibition  activity-dependent conformational changes   Constitutive signal bias mediated by the human GHRHR splice variant 1 期刊论文  OAI收割 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2021, 卷号: 118, 期号: 40, 页码: 10 作者:  Cong, Zhaotong;  Zhou, Fulai;  Zhang, Chao;  Zou, Xinyu;  Zhang, Huibing   |  收藏  |  浏览/下载：57/0  |  提交时间：2021/12/01 class B1 GPCR  receptor bias  cancer  cell proliferation   Insights into agonist-elicited activation of the human glucose-dependent insulinotropic polypeptide receptor 期刊论文  OAI收割 BIOCHEMICAL PHARMACOLOGY, 2021, 卷号: 192, 页码: 16 作者:  Yuliantie, Elita;  van der Velden, Wijnand J. C.;  Labroska, Viktorija;  Dai, Antao;  Zhao, Fenghui   |  收藏  |  浏览/下载：94/0  |  提交时间：2021/11/04 Glucose-dependent insulinotropic polypeptide receptor  G protein-coupled receptor  GPCR structure-function relationship  ERK  cAMP  Arrestin   Discovery of a Potential Liver Fibrosis Inhibitor from a Mushroom Endophytic Fungus by Genome Mining of a Silent Biosynthetic Gene Cluster 期刊论文  OAI收割 JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2021, 卷号: 69, 期号: 38, 页码: 11303-11310 作者:  Cheng, Jin-Tao;  Wang, Han-Min;  Yu, Jia-Hui;  Sun, Chen-Fan;  Cao, Fei   |  收藏  |  浏览/下载：24/0  |  提交时间：2021/12/01 fungus  Calcarisporium arbuscula  natural product  gene cluster activation  liver fibrosis   Ligand recognition and G-protein coupling selectivity of cholecystokinin A receptor 期刊论文  OAI收割 NATURE CHEMICAL BIOLOGY, 2021, 卷号: 17, 期号: 12, 页码: 1238-1244 作者:  Liu, Qiufeng;  Yang, Dehua;  Zhuang, Youwen;  Croll, Tristan I.;  Cai, Xiaoqing   |  收藏  |  浏览/下载：14/0  |  提交时间：2024/03/22 a Receptor  Structural Basis  Binding-site  Cck1 Receptor  Agonist  Activation  Mechanism  Optimization  Discovery  Rat