机构

• 上海药物研究所 [19]

采集方式

• OAI收割 [19]

内容类型

• 期刊论文 [19]

发表日期

• 2023 [6]
• 2022 [6]
• 2021 [3]
• 2019 [1]
• 2018 [1]
• 2014 [1]
• 更多

学科主题

筛选

浏览/检索结果: 共19条，第1-10条 帮助 限定条件 专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择题名升序题名降序提交时间升序提交时间降序作者升序作者降序发表日期升序发表日期降序 Discovery of 5-trifluoromethyl-2-aminopyrimidine derivatives as potent dual inhibitors of FLT3 and CHK1 期刊论文  OAI收割 RSC MEDICINAL CHEMISTRY, 2023, 页码: 14 作者:  Deng, Minjie;  Gao, Yue;  Wang, Peipei;  Du, Wenjing;  Xu, Gaoya   |  收藏  |  浏览/下载：7/0  |  提交时间：2024/02/19 Design, synthesis and biological evaluation of 2-aminopyrimidine derivatives as potent FLT3 inhibitors 期刊论文  OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2023, 卷号: 96, 页码: 5 作者:  Lian, Xuanmin;  Gao, Yue;  Li, Xuemei;  Wang, Peipei;  Tong, Lexian   |  收藏  |  浏览/下载：6/0  |  提交时间：2023/12/11 2-aminopyrimidine  FLT3 inhibitors  MV4-11  FLT3 mutations   Discovery of 2-Aminopyrimidine Derivatives as Potent Dual FLT3/CHK1 Inhibitors with Significantly Reduced hERG Inhibitory Activities 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2023, 页码: 23 作者:  Li, Xuemei;  Wang, Peipei;  Wang, Chang;  Jin, Tingting;  Xu, Ran   |  收藏  |  浏览/下载：14/0  |  提交时间：2023/10/17 Discovery of pyrido[4,3-d]pyrimidinone derivatives as novel Wee1 inhibitors 期刊论文  OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY, 2023, 卷号: 87, 页码: 12 作者:  Ye, Qingqing;  Ma, Jingkun;  Wang, Peipei;  Wang, Chang;  Sun, Mei   |  收藏  |  浏览/下载：10/0  |  提交时间：2023/10/17 Wee1 inhibitor  Scaffold hopping   Design, Synthesis, and Biological Evaluation of 2-Aminothiazole Derivatives as Novel Checkpoint Kinase 1 (CHK1) Inhibitors 期刊论文  OAI收割 CHEMMEDCHEM, 2023, 页码: 19 作者:  Deng, Minjie;  Wang, Peipei;  Long, Xiubing;  Xu, Gaoya;  Wang, Chang   |  收藏  |  浏览/下载：14/0  |  提交时间：2023/04/10 2-aminothiazole  CHK1 inhibitors  antiproliferation  hematologic malignancies  biological activity   Design, synthesis, and evaluation of pyrido.[3,4-b]pyrazin-2(1H)-one derivatives as potent FLT3 inhibitors 期刊论文  OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY, 2023, 卷号: 79, 页码: 117155 作者:  Sun, Mei;  Wang, Chang;  Wang, Peipei;  Ye, Qingqing;  Zhou, Yubo   |  收藏  |  浏览/下载：2/0  |  提交时间：2024/04/09 FLT3  FLT3-D835Y  Acute myeloid leukemia  Structure -activity relationships   Dual inhibition of CHK1/FLT3 enhances cytotoxicity and overcomes adaptive and acquired resistance in FLT3-ITD acute myeloid leukemia 期刊论文  OAI收割 LEUKEMIA, 2022, 页码: 11 作者:     |  收藏  |  浏览/下载：19/0  |  提交时间：2023/04/10 Design, synthesis, and biological evaluation of Wee1 kinase degraders 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 243, 页码: 21 作者:  Zhu, Shulei;  Liu, Jieyu;  Xiao, Donghuai;  Wang, Peipei;  Ma, Jingkun   |  收藏  |  浏览/下载：34/0  |  提交时间：2022/11/11 CRBN  Wee1  PROTAC  Degradation   General Pharmacological Activation Mechanism of K+ Channels Bypassing Channel Gates 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2022, 页码: 15 作者:  Liu, Shijie;  Guo, Peipei;  Wang, Kun;  Zhang, Shaoying;  Li, Ya   |  收藏  |  浏览/下载：39/0  |  提交时间：2022/08/30 Structures of the Omicron spike trimer with ACE2 and an anti-Omicron antibody 期刊论文  OAI收割 SCIENCE, 2022, 卷号: 375, 期号: 6584, 页码: 1048-+ 作者:  Yin, Wanchao;  Xu, Youwei;  Xu, Peiyu;  Cao, Xiaodan;  Wu, Canrong   |  收藏  |  浏览/下载：37/0  |  提交时间：2022/06/15