中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [425]
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OAI收割 [425]
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期刊论文 [412]
会议论文 [12]
专利 [1]
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2024 [5]
2023 [28]
2022 [27]
2021 [46]
2020 [29]
2019 [24]
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专题:上海药物研究所
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Ent-labdane-type diterpene glycosides obtained from
Rubus
chingii
Hu and their inhibitory effects on PDE5A activity
期刊论文
OAI收割
FITOTERAPIA, 2024, 卷号: 173, 页码: 14
作者:
Yu, Jun-dong
;
Wang, Jing-Yi
;
Liu, Jia-yuan
;
Xu, Ye-chun
;
Zhang, Xue
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2024/02/27
diterpene glycosides
Rubus Chingii Hu
PDE5A inhibitory activity
ent-labdane
Molecular features of the ligand-free GLP-1R, GCGR and GIPR in complex with G
s
proteins
期刊论文
OAI收割
CELL DISCOVERY, 2024, 卷号: 10, 期号: 1, 页码: 13
作者:
Cong, Zhaotong
;
Zhao, Fenghui
;
Li, Yang
;
Luo, Gan
;
Mai, Yiting
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2024/03/13
DRAK2 suppresses autophagy by phosphorylating ULK1 at Ser
56
to diminish pancreatic β cell function upon overnutrition
期刊论文
OAI收割
SCIENCE TRANSLATIONAL MEDICINE, 2024, 卷号: 16, 期号: 733, 页码: 16
作者:
Lu, Yuting
;
Xu, Junyu
;
Li, Yufeng
;
Wang, Ruoran
;
Dai, Chengqiu
  |  
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2024/03/13
Pharmacologically significant constituents collectively responsible for anti-sepsis action of XueBiJing, a Chinese herb-based intravenous formulation
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2024, 页码: 16
作者:
Cheng, Chen
;
Ren, Chao
;
Li, Mu-zi
;
Liu, Yi-hui
;
Yao, Ren-qi
  |  
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2024/02/27
Traditional Chinese medicine
XueBiJing
sepsis
mortality
pharmacokinetic compatibility
polypharmacology
Red blood cell membrane biomimetic nanoprobes for ratiometric imaging of reactive oxygen species level in atherosclerosis
期刊论文
OAI收割
CHEMICAL ENGINEERING JOURNAL, 2024, 卷号: 479, 页码: 14
作者:
Liu, Bo
;
Han, Gui-Mei
;
Wang, Dong-Xia
;
Liu, Ding -Bin
;
Liu, An -An
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2024/03/25
Atherosclerosis
Reactive oxygen species
Biomimetic nanoprobes
In situ
Ratiometric imaging
Physiological and Pathological Functions of TRPM7 Channel and Its Small-molecule Modulators
期刊论文
OAI收割
PROGRESS IN BIOCHEMISTRY AND BIOPHYSICS, 2023, 卷号: 50, 期号: 12, 页码: 2856-2868
作者:
Wang, Yun-Qi
;
Guan, Zi-Yue
;
Gao, Zhao-Bing
;
Zheng, Yue-Ming
  |  
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2024/04/09
TRPM7
ion channel
physiological function
disease
small molecule modulators
Total synthesis of (±)-villosin C and (±)-teuvincenone B
期刊论文
OAI收割
ORGANIC CHEMISTRY FRONTIERS, 2023, 页码: 5
作者:
Zhou, Jin-Xin
;
Yan, Ming-Jie
;
Shi, Xiao-Yu
;
Wang, Yue-Qi
;
Shen, Hong-Yan
  |  
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2024/01/16
Sterically demanding Csp
2
(ortho-substitution)-Csp
3
(tertiary) bond formation via carboxylate-directed Mizoroki-Heck reaction under extra-ligand-free conditions
期刊论文
OAI收割
ORGANIC & BIOMOLECULAR CHEMISTRY, 2023, 页码: 5
作者:
Zeng, Wei
;
Chen, Ai-Wen
;
Yan, Ming-Jie
;
Wang, Jie
  |  
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2024/01/16
TI17, a novel compound, exerts anti-MM activity by impairing Trip13 function of DSBs repair and enhancing DNA damage
期刊论文
OAI收割
CANCER MEDICINE, 2023, 页码: 14
作者:
Chang, Shuaikang
;
Xiao, Wenqin
;
Xie, Yongsheng
;
Xu, Zhijian
;
Li, Bo
  |  
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2023/12/11
DNA damage
DSBs repair
myeloma
TI17
Trip13
Identification of [1,2,4]Triazolo[4,3-a]pyrazine PARP1 inhibitors with overcome acquired resistance activities
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 259, 页码: 19
作者:
Wang, Pingyuan
;
Zhu, Wen-Ting
;
Wang, Yajing
;
Song, Shan-Shan
;
Xi, Yong
  |  
收藏
  |  
浏览/下载:58/0
  |  
提交时间:2023/10/17
PARP1 inhibitor
Synthetic lethality
Drug resistance
Anticancer
Structure -activity relationship