中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [105]
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OAI收割 [105]
内容类型
期刊论文 [95]
会议论文 [10]
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2024 [1]
2023 [8]
2022 [11]
2021 [5]
2020 [6]
2019 [4]
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Chemistry [1]
Pharmacolo... [1]
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专题:上海药物研究所
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Novel imidazo[1,2,4] triazole derivatives: Synthesis, fluorescence, bioactivity for SHP1
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 265, 页码: 15
作者:
Yan, Xue
;
Zhang, Chun
;
Gao, Li-Xin
;
Liu, Min -Min
;
Yang, Yu-Ting
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2024/02/27
Imidazo[124] triazole derivatives
Fluorescence property
SHP1
Bioactivity
Cellular imaging
Preclinical and early clinical studies of a novel compound SYHA1813 that efficiently crosses the blood-brain barrier and exhibits potent activity against glioblastoma
期刊论文
OAI收割
ACTA PHARMACEUTICA SINICA B, 2023, 卷号: 13, 期号: 12, 页码: 4748-4764
作者:
Liu, Yingqiang
;
Zhan, Zhengsheng
;
Kang, Zhuang
;
Li, Mengyuan
;
Lv, Yongcong
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2024/01/26
Small molecule inhibitor
Tumor microenvironment
Immune-checkpoint
immune-deficient mouse models
including temozolomide (TMZ) insensitive tumors. Notably
Indole-3-Propionic Acid, a Gut Microbiota Metabolite, Protects Against the Development of Postoperative Delirium
期刊论文
OAI收割
ANNALS OF SURGERY, 2023, 卷号: 278, 期号: 6, 页码: E1164-E1174
作者:
Zhou, Xue
;
Wu, Xinbo
;
Wu, Yan
;
Yang, Liuyue
;
Shi, Eleanor
  |  
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2024/04/09
gut microbiota
indole-3-propionic acid
anesthesia
surgery
postoperative delirium
Identification of [1,2,4]Triazolo[4,3-a]pyrazine PARP1 inhibitors with overcome acquired resistance activities
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 259, 页码: 19
作者:
Wang, Pingyuan
;
Zhu, Wen-Ting
;
Wang, Yajing
;
Song, Shan-Shan
;
Xi, Yong
  |  
收藏
  |  
浏览/下载:58/0
  |  
提交时间:2023/10/17
PARP1 inhibitor
Synthetic lethality
Drug resistance
Anticancer
Structure -activity relationship
Comparative Characterization of the Ginsenosides from Six Panax Herbal Extracts and Their In Vitro Rat Gut Microbial Metabolites by Advanced Liquid Chromatography-Mass Spectrometry Approaches
期刊论文
OAI收割
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2023, 卷号: 71, 期号: 24, 页码: 9391-9403
作者:
Mi, Yue-Guang
;
Xu, Xiao-Yan
;
Hong, Li-Li
;
Jiang, Mei-Ting
;
Chen, Bo-Xue
  |  
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2023/10/17
Panax
multicomponent characterization
quantitative assay
gut microbiota
in vitro biotransformation
liquid chromatography-massspectrometry
A study on optical properties of various hot drug molecules by 2020
期刊论文
OAI收割
NEW JOURNAL OF CHEMISTRY, 2023, 卷号: 47, 期号: 21, 页码: 10046-10060
作者:
Zhang, Chun
;
Yang, Yuting
;
Yan, Xue
;
Sun, Yi-Tao
;
Shao, Andong
  |  
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2023/10/17
Identification of lignans as ATP citrate lyase (ACLY) inhibitors from the roots of Pouzolzia zeylanica
期刊论文
OAI收割
NATURAL PRODUCT RESEARCH, 2023, 页码: 8
作者:
Li, Jin-Long
;
Jiang, Jia-Yi
;
Gu, Shan-Shan
;
Zhang, Lei
;
Sun, Yan
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2023/10/17
Pouzolzia zeylanica
lignans
ATP citrate lyase (ACLY) inhibitors
Thioparib inhibits homologous recombination repair, activates the type I IFN response, and overcomes olaparib resistance
期刊论文
OAI收割
EMBO MOLECULAR MEDICINE, 2023, 页码: 24
作者:
Wang, Li-Min
;
Wang, Pingyuan
;
Chen, Xiao-Min
;
Yang, Hui
;
Song, Shan-Shan
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2023/04/10
homologous recombination repair
olaparib-resistant
PARP inhibitor
PARP7
type I interferons
Advances in Medicinal Chemistry of Estrogen-related Receptor Alpha (ERRa) Inverse Agonists
期刊论文
OAI收割
CURRENT TOPICS IN MEDICINAL CHEMISTRY, 2023, 卷号: 23, 期号: 20, 页码: 1952-1963
作者:
Zhang, Haibin
;
Du, Yongli
;
Zheng, Yong
;
Lv, Huiting
  |  
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2023/10/17
ERRalpha
ERRalpha inverse agonists
Breast cancer
TNBC
Signaling pathways
Inverse agonistic activity
Radical C-H Sulfonation of Arenes: Its Applications on Bioactive and DNA-Encoded Molecules
期刊论文
OAI收割
ORGANIC LETTERS, 2022, 页码: 6
作者:
Zhang, Yue
;
Xia, Shengdi
;
Shi, Wen-xia
;
Lin, Bizhen
;
Su, Xiao-can
  |  
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2022/12/13