机构

• 上海药物研究所 [52]

采集方式

• OAI收割 [52]

内容类型

• 期刊论文 [52]

发表日期

• 2024 [1]
• 2023 [2]
• 2022 [6]
• 2021 [8]
• 2020 [6]
• 2019 [4]
• 更多

学科主题

筛选

浏览/检索结果: 共52条，第1-10条 帮助 限定条件 专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择提交时间升序提交时间降序发表日期升序发表日期降序题名升序题名降序作者升序作者降序 SIBP-03, a novel anti-HER3 antibody, exerts antitumor effects and synergizes with EGFR- and HER2-targeted drugs 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2024, 页码: 10 作者:  Li, Wen-jing;  Xie, Cheng-ying;  Zhu, Xi;  Tang, Jiao;  Wang, Lei   |  收藏  |  浏览/下载：4/0  |  提交时间：2024/02/19 SIBP-03  HER3  HER3-targeted therapy  neuregulin 1  EGFR  HER2   Dihydrocelastrol induces antitumor activity and enhances the sensitivity of bortezomib in resistant multiple myeloma by inhibiting STAT3-dependent PSMB5 regulation 期刊论文  OAI收割 ACTA BIOCHIMICA ET BIOPHYSICA SINICA, 2023, 卷号: 55, 期号: 12, 页码: 1884-1891 作者:  Jin, Shuhan;  Li, Bo;  Zhang, Bibo;  Gao, Xuejie;  Jia, Xinyan   |  收藏  |  浏览/下载：11/0  |  提交时间：2024/02/27 dihydrocelastrol  multiple myeloma  JAK2/STAT3  PSMB5  bortezomib resistance   Deciphering the functional landscape of phosphosites with deep neural network 期刊论文  OAI收割 CELL REPORTS, 2023, 卷号: 42, 期号: 9, 页码: 23 作者:  Liang, Zhongjie;  Liu, Tonghai;  Li, Qi;  Zhang, Guangyu;  Zhang, Bei   |  收藏  |  浏览/下载：9/0  |  提交时间：2023/12/08 Leveraging Protein Dynamics to Identify Functional Sites Models 期刊论文  OAI收割 JOURNAL OF CHEMICAL INFORMATION AND MODELING, 2022, 卷号: 62, 期号: 14, 页码: 3331-3345 作者:  Zhu, Fei;  Yang, Sijie;  Meng, Fanwang;  Zheng, Yuxiang;  Ku, Xin   |  收藏  |  浏览/下载：23/0  |  提交时间：2022/11/11 Leveraging Protein Dynamics to Identify Functional Phosphorylation Sites using Deep Learning Models 期刊论文  OAI收割 JOURNAL OF CHEMICAL INFORMATION AND MODELING, 2022, 页码: 15 作者:  Zhu, Fei;  Yang, Sijie;  Meng, Fanwang;  Zheng, Yuxiang;  Ku, Xin   |  收藏  |  浏览/下载：11/0  |  提交时间：2023/04/10 Pharmacokinetics, mass balance, and metabolism of [C-14]TPN171, a novel PDE5 inhibitor, in humans for the treatment of pulmonary arterial hypertension 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2022, 页码: 13 作者:  He, Yi-fei;  Liu, Yin;  Yu, Jing-hua;  Cheng, Huan;  Odilov, Abdullajon   |  收藏  |  浏览/下载：31/0  |  提交时间：2022/08/16 TPN171  [C-14]TPN171  PDE5 inhibitor  pulmonary arterial hypertension  healthy volunteers  pharmacokinetics  metabolite identification  mass balance   Discovery of a highly potent CECR2 bromodomain inhibitor with 7H-pyrrolo[2,3-d] pyrimidine scaffold 期刊论文  OAI收割 BIOORGANIC CHEMISTRY, 2022, 卷号: 123, 页码: 12 作者:  Lu, Haibo;  Lu, Tian;  Zu, Shijia;  Duan, Zhe;  Guang, Yiman   |  收藏  |  浏览/下载：24/0  |  提交时间：2022/08/16 CECR2 bromodomain  BPTF bromodomain  Small-molecule inhibitor  SAR study  Chemical probe   HSP90 N-terminal inhibitors target oncoprotein MORC2 for autophagic degradation and suppress MORC2-driven breast cancer progression 期刊论文  OAI收割 CLINICAL AND TRANSLATIONAL MEDICINE, 2022, 卷号: 12, 期号: 5, 页码: 18 作者:  Yang, Fan;  Sun, Rui;  Hou, Zeng;  Zhang, Fang-Lin;  Xiao, Yi   |  收藏  |  浏览/下载：39/0  |  提交时间：2022/06/15 breast cancer  chaperone-mediated autophagy  HSP90 inhibitor  MORC2  protein degradation   Selective bromodomain and extra-terminal bromodomain inhibitor inactivates macrophages and hepatic stellate cells to inhibit liver inflammation and fibrosis 期刊论文  OAI收割 BIOENGINEERED, 2022, 卷号: 13, 期号: 4, 页码: 10914-10930 作者:  Fu, Rong;  Zu, Shi-Jia;  Liu, Yan-Jun;  Li, Jia-Cheng;  Dang, Wen-Zhen   |  收藏  |  浏览/下载：33/0  |  提交时间：2022/06/15 BET inhibitor  macrophage  hepatic stellate cell  inflammation  fibrosis   Design, synthesis and biological evaluation of a novel spiro oxazolidinedione as potent p300/CBP HAT inhibitor for the treatment of ovarian cancer 期刊论文  OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY, 2021, 卷号: 52, 页码: 12 作者:  Ding, Hong;  Pei, Yuan;  Li, Yuanqing;  Xu, Wen;  Mei, Lianghe   |  收藏  |  浏览/下载：37/0  |  提交时间：2022/06/15 Epigenetics  Histone acetyltransferase  P300/CBP  Ovarian cancer