机构

• 上海药物研究所 [33]

采集方式

• OAI收割 [33]

内容类型

• 期刊论文 [33]

发表日期

• 2023 [3]
• 2022 [2]
• 2021 [3]
• 2020 [1]
• 2019 [1]
• 2018 [3]
• 更多

学科主题

• Chemistry [1]
• Pharmacolo... [1]

筛选

浏览/检索结果: 共33条，第1-10条 帮助 限定条件 专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择提交时间升序提交时间降序发表日期升序发表日期降序题名升序题名降序作者升序作者降序 Structure-based drug discovery of novel fused- pyrazolone carboxamide derivatives as potent and selective AXL inhibitors 期刊论文  OAI收割 ACTA PHARMACEUTICA SINICA B, 2023, 卷号: 13, 期号: 12, 页码: 4918-4933 作者:  Fang, Feifei;  Dai, Yang;  Wang, Hao;  Ji, Yinchun;  Liang, Xuewu   |  收藏  |  浏览/下载：7/0  |  提交时间：2024/01/26 derivatives  Antitumor drug development  Potential AXL inhibitor  Antitumor activity  Structure-based drug design  Fused-pyrazolone carboxamide   Oxygenated Cembrane Diterpenes from the South China Sea Soft Coral Sinularia tumulosa 期刊论文  OAI收割 CHEMISTRY & BIODIVERSITY, 2023, 页码: 5 作者:  Zhu, Sheng-Hui;  Yu, Dan-Dan;  Su, Ming-Zhi;  Luo, Hui;  Yao, Li-Gong   |  收藏  |  浏览/下载：9/0  |  提交时间：2023/10/17 antibacterial activity  cembrane diterpene  Sinularia tumulosa  soft coral  structural elucidation   Antitumor Cembrane Diterpenoids from the South China Sea Soft Coral Lobophytum sp. 期刊论文  OAI收割 CHEMISTRY & BIODIVERSITY, 2023, 卷号: 20, 期号: 4 作者:  Song, Yu-Ting;  Yu, Dan-Dan;  Zhi Su, Ming;  Luo, Hui;  Cao, Jian-Guo   |  收藏  |  浏览/下载：3/0  |  提交时间：2024/03/27 soft coral  Lobophytum sp  cembranoids  configuration determination  antitumor activity   Discovery and characterization of a novel cGAS covalent inhibitor for the treatment of inflammatory bowel disease 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2022, 页码: 10 作者:  Song, Jia;  Yang, Rui-rui;  Chang, Jie;  Liu, Ya-dan;  Lu, Cheng-hao   |  收藏  |  浏览/下载：48/0  |  提交时间：2022/11/11 cyclic GMP-AMP synthase  covalent inhibitor  inflammatory bowel disease  high-throughput screening   Loss of SIRT5 promotes bile acid-induced immunosuppressive microenvironment and hepatocarcinogenesis 期刊论文  OAI收割 JOURNAL OF HEPATOLOGY, 2022, 卷号: 77, 期号: 2, 页码: 453-466 作者:  Sun, Renqiang;  Zhang, Zhiyong;  Bao, Ruoxuan;  Guo, Xiaozhen;  Gu, Yuan   |  收藏  |  浏览/下载：12/0  |  提交时间：2024/03/21 SIRT5  bile acid  macrophage polarization  immunosuppressive tumor microenvironment  liver cancer   Anxiolytic effect of GABAergic neurons in the anterior cingulate cortex in a rat model of chronic inflammatory pain 期刊论文  OAI收割 MOLECULAR BRAIN, 2021, 卷号: 14, 期号: 1, 页码: 22 作者:  Shao, Fang-bing;  Fang, Jun-fan;  Wang, Si-si;  Qiu, Meng-ting;  Xi, Dan-ning   |  收藏  |  浏览/下载：58/0  |  提交时间：2021/11/04 Chronic inflammatory pain  Anxiety-like behavior  GABAergic system  Anterior cingulate cortex  synaptic transmission   SARS-CoV-2 envelope protein causes acute respiratory distress syndrome (ARDS)-like pathological damages and constitutes an antiviral target 期刊论文  OAI收割 CELL RESEARCH, 2021, 页码: 14 作者:  Xia, Bingqing;  Shen, Xurui;  He, Yang;  Pan, Xiaoyan;  Liu, Feng-Liang   |  收藏  |  浏览/下载：74/0  |  提交时间：2021/08/17 An integrative drug repositioning framework discovered a potential therapeutic agent targeting COVID-19 期刊论文  OAI收割 SIGNAL TRANSDUCTION AND TARGETED THERAPY, 2021, 卷号: 6, 期号: 1, 页码: 16 作者:  Ge, Yiyue;  Tian, Tingzhong;  Huang, Suling;  Wan, Fangping;  Li, Jingxin   |  收藏  |  浏览/下载：28/0  |  提交时间：2022/06/15 Structural basis of GPBAR activation and bile acid recognition 期刊论文  OAI收割 NATURE, 2020, 页码: 29 作者:  Yang, Fan;  Mao, Chunyou;  Guo, Lulu;  Lin, Jingyu;  Ming, Qianqian   |  收藏  |  浏览/下载：29/0  |  提交时间：2020/12/24 Identification of a new inhibitor of KRAS-PDE delta interaction targeting KRAS mutant nonsmall cell lung cancer 期刊论文  OAI收割 INTERNATIONAL JOURNAL OF CANCER, 2019, 卷号: 145, 期号: 5, 页码: 1334-1345 作者:  Leung, Elaine Lai-Han;  Luo, Lian Xiang;  Li, Ying;  Liu, Zhong-Qiu;  Li, Lan Lan   |  收藏  |  浏览/下载：32/0  |  提交时间：2020/07/01