机构

• 上海药物研究所 [232]

采集方式

• OAI收割 [232]

内容类型

• 期刊论文 [227]
• 会议论文 [5]

发表日期

• 2024 [6]
• 2023 [9]
• 2022 [17]
• 2021 [18]
• 2020 [12]
• 2019 [12]
• 更多

学科主题

• Oncology [4]
• Pharmacolo... [4]
• Chemistry [2]

筛选

浏览/检索结果: 共232条，第1-10条 帮助 限定条件 专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择提交时间升序提交时间降序发表日期升序发表日期降序题名升序题名降序作者升序作者降序 Nanobodies as negative allosteric modulators for human calcium sensing receptor 期刊论文  OAI收割 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2024, 卷号: 695, 页码: 9 作者:  Cui, Qianqian;  Wang, Lu;  Wang, Haonan;  Chen, Xiaochen;  Han, Li   |  收藏  |  浏览/下载：16/0  |  提交时间：2024/04/09 G-protein-coupled receptor  Extracellular calcium sensing receptor  Nanobody  Cryo-electron microscope  Systemic Ca 2+homoeostasis   An LQT2-related mutation in the voltage-sensing domain is involved in switching the gating polarity of hERG 期刊论文  OAI收割 BMC BIOLOGY, 2024, 卷号: 22, 期号: 1, 页码: 14 作者:  Liu, Zhipei;  Wang, Feng;  Yuan, Hui;  Tian, Fuyun;  Yang, Chuanyan   |  收藏  |  浏览/下载：13/0  |  提交时间：2024/03/13 hERG  K525N  Gating Polarity  Voltage-Sensing Domain  LQT2   Pharmacologically significant constituents collectively responsible for anti-sepsis action of XueBiJing, a Chinese herb-based intravenous formulation 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2024, 页码: 16 作者:  Cheng, Chen;  Ren, Chao;  Li, Mu-zi;  Liu, Yi-hui;  Yao, Ren-qi   |  收藏  |  浏览/下载：11/0  |  提交时间：2024/02/27 Traditional Chinese medicine  XueBiJing  sepsis  mortality  pharmacokinetic compatibility  polypharmacology   EPHA2 feedback activation limits the response to PDEδ inhibition in KRAS-dependent cancer cells (vol 41, pg 270, 2020) 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2024, 页码: 2 作者:  Chen, Yue-hong;  Lv, Hao;  Shen, Ning;  Wang, Xiao-min;  Tang, Shuai   |  收藏  |  浏览/下载：20/0  |  提交时间：2024/03/06 A novel capsid-XL32-derived adeno-associated virus serotype prompts retinal tropism and ameliorates choroidal neovascularization 期刊论文  OAI收割 BIOMATERIALS, 2024, 卷号: 304, 页码: 13 作者:  Luo, Lin-Lin;  Xu, Jie;  Wang, Bing-Qiao;  Chen, Chen;  Chen, Xi   |  收藏  |  浏览/下载：9/0  |  提交时间：2024/01/26 AAV  Capsid engineering  Phosphosites mutation  Retinal tropism  Neovascularization   Red blood cell membrane biomimetic nanoprobes for ratiometric imaging of reactive oxygen species level in atherosclerosis 期刊论文  OAI收割 CHEMICAL ENGINEERING JOURNAL, 2024, 卷号: 479, 页码: 14 作者:  Liu, Bo;  Han, Gui-Mei;  Wang, Dong-Xia;  Liu, Ding -Bin;  Liu, An -An   |  收藏  |  浏览/下载：13/0  |  提交时间：2024/03/25 Atherosclerosis  Reactive oxygen species  Biomimetic nanoprobes  In situ  Ratiometric imaging   Multiple heart-cutting two-dimensional liquid chromatography/charged aerosol detector assay of ginsenosides for quality evaluation of ginseng from diverse Chinese patent medicines 期刊论文  OAI收割 JOURNAL OF CHROMATOGRAPHY A, 2023, 卷号: 1708, 页码: 10 作者:  Xu, Xiao-yan;  Jiang, Mei-ting;  Wang, Yu;  Sun, He;  Jing, Qi   |  收藏  |  浏览/下载：10/0  |  提交时间：2023/12/08 Multiple heart -cutting two-dimensional liquid  chromatography  Charged aerosol detector  Quantitative assay  Ginseng  Chinese patent medicine   Anxiolytic effect of antidiabetic metformin is mediated by AMPK activation in mPFC inhibitory neurons 期刊论文  OAI收割 MOLECULAR PSYCHIATRY, 2023, 页码: 11 作者:  Zhang, Yong-mei;  Zong, Hai-chao;  Qi, Ying-bei;  Chang, Liu-liu;  Gao, Ya-nan   |  收藏  |  浏览/下载：10/0  |  提交时间：2023/12/08 Discovery, structural optimization, and anti-tumor bioactivity evaluations of betulinic acid derivatives as a new type of ROR & gamma; antagonists 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 257, 页码: 15 作者:  Mei, Lianghe;  Xu, Lansong;  Wu, Sanan;  Wang, Yafang;  Xu, Chao   |  收藏  |  浏览/下载：39/0  |  提交时间：2023/10/17 Betulinic acid  ROR & gamma  Target identification  Rationale structure optimization  Anti-tumor effects  antagonists   Preclinical Evaluation of 9MW2821, a Site-Specific Monomethyl Auristatin E-based Antibody-Drug Conjugate for Treatment of Nectin-4-expressing Cancers 期刊论文  OAI收割 MOLECULAR CANCER THERAPEUTICS, 2023, 卷号: 22, 期号: 8, 页码: 913-925 作者:  Zhou, Wei;  Fang, Peng;  Yu, Dongan;  Ren, Hongyuan;  You, Meng   |  收藏  |  浏览/下载：11/0  |  提交时间：2023/10/17