中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [201]
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OAI收割 [201]
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期刊论文 [198]
会议论文 [3]
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2024 [5]
2023 [19]
2022 [15]
2021 [26]
2020 [23]
2019 [22]
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Pharmacolo... [5]
Oncology [2]
Chemistry [1]
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专题:上海药物研究所
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Inulin-like polysaccharide ABWW may impede CCl
4
induced hepatic stellate cell activation through mediating the FAK/PI3K/AKT signaling pathway
in vitro
&
in vivo
期刊论文
OAI收割
CARBOHYDRATE POLYMERS, 2024, 卷号: 326, 页码: 15
作者:
Dai, Xiaolan
;
Du, Zhenyun
;
Jin, Can
;
Tang, Bixi
;
Chen, Xia
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2024/02/19
Fructan
Hepatic fibrosis
Hepatic stellate cells
FAK/PI3K/AKT
Palladium-Catalyzed Deuteration of Arylketone Oxime Ethers
期刊论文
OAI收割
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2024, 页码: 7
作者:
Wang, Zhen-Yu
;
Zhang, Xu
;
Chen, Wen-Qing
;
Sun, Guo-Dong
;
Wang, Xing
  |  
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2024/03/13
C-C Bond Cleavage
Deacylation
Regioselective Deuteration
Difunctionalization
Palladium Catalysis
DRAK2 suppresses autophagy by phosphorylating ULK1 at Ser
56
to diminish pancreatic β cell function upon overnutrition
期刊论文
OAI收割
SCIENCE TRANSLATIONAL MEDICINE, 2024, 卷号: 16, 期号: 733, 页码: 16
作者:
Lu, Yuting
;
Xu, Junyu
;
Li, Yufeng
;
Wang, Ruoran
;
Dai, Chengqiu
  |  
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2024/03/13
Nanobodies as negative allosteric modulators for human calcium sensing receptor
期刊论文
OAI收割
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2024, 卷号: 695, 页码: 9
作者:
Cui, Qianqian
;
Wang, Lu
;
Wang, Haonan
;
Chen, Xiaochen
;
Han, Li
  |  
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2024/04/09
G-protein-coupled receptor
Extracellular calcium sensing receptor
Nanobody
Cryo-electron microscope
Systemic Ca 2+homoeostasis
Direct Construction of
C
-Alkyl Glycosides from Non-Activated Olefins via Nickel-Catalyzed C(sp
3
)―C(sp
3
) Coupling Reaction
期刊论文
OAI收割
ADVANCED SCIENCE, 2024, 页码: 8
作者:
Yu, Changyue
;
Xu, Yinghuan
;
Zeng, Mingjie
;
Wang, Jingjing
;
Dai, Wenhao
  |  
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2024/02/27
C-alkyl glycosides
C(sp3)C(sp3) coupling
non-activated olefins
nickel catalysis
Total Synthesis of Syringin and Its Natural Analogues via C-C Bond Activation of Aryl Ketones
期刊论文
OAI收割
CHINESE JOURNAL OF CHEMISTRY, 2023, 卷号: 41, 期号: 24, 页码: 3587-3592
作者:
Wang, Zhen-Yu
;
Sun, Yi
;
Sun, Guo-Dong
;
Xu, Hui
;
Dai, Hui-Xiong
  |  
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2024/02/27
Syringin
Total synthesis
Cross-coupling
C-C activation
Syringin analogues
Structure-based drug discovery of novel fused- pyrazolone carboxamide derivatives as potent and selective AXL inhibitors
期刊论文
OAI收割
ACTA PHARMACEUTICA SINICA B, 2023, 卷号: 13, 期号: 12, 页码: 4918-4933
作者:
Fang, Feifei
;
Dai, Yang
;
Wang, Hao
;
Ji, Yinchun
;
Liang, Xuewu
  |  
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2024/01/26
derivatives
Antitumor drug development
Potential AXL inhibitor
Antitumor activity
Structure-based drug design
Fused-pyrazolone carboxamide
An ultra-compact promoter drives widespread neuronal expression in mouse and monkey brains
期刊论文
OAI收割
CELL REPORTS, 2023, 卷号: 42, 期号: 11, 页码: 21
作者:
Wang, Jingyi
;
Lin, Jianbang
;
Chen, Yefei
;
Liu, Jing
;
Zheng, Qiongping
  |  
收藏
  |  
浏览/下载:35/0
  |  
提交时间:2024/01/16
Circuit-specific gene therapy reverses core symptoms in a primate Parkinson's disease model
期刊论文
OAI收割
CELL, 2023, 卷号: 186, 期号: 24, 页码: 5394-+
作者:
Chen, Yefei
;
Hong, Zexuan
;
Wang, Jingyi
;
Liu, Kunlin
;
Liu, Jing
  |  
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2024/01/26
Vitamin B2-Based Ferroptosis Promoter for Sono-Enhanced Nanocatalytic Therapy of Triple-Negative Breast Cancer
期刊论文
OAI收割
ADVANCED FUNCTIONAL MATERIALS, 2023, 页码: 12
作者:
Zhou, Mengjiao
;
Yuan, Minjian
;
Jin, Yilan
;
Zhou, Qianqian
;
Yu, Yuting
  |  
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2023/12/08
ferroptosis
nanocatalytic therapy
oxidative stress
redox homeostasis